Brachycephaly is a kind of craniosynostosis. Because of premature closure of the coronal suture, the skull is shorter in the anteroposterior diameter but is widened with a high vault and the occiput and forehead are flattened. Diabetes insipidus had been reported in oxycephaly. We have experienced a case of central diabetes insipidus associated with brachycephaly. A brief review of related literatures is included in this report.
Craniosynostoses* ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic* ; Forehead ; Skull ; Sutures

Polyuria is occasionally observed after general anesthesia with sevoflurane. Usually the onset of polyuria is abrupt and remission is spontaneous, so it's not so easy to do detailed investigation. The authors came across with two cases of polyuria during general anesthesia with sevoflurane which occurred so early around one hour after induction of anesthesia. Both cases revealed no special problem like central diabetes insipidus.
Anesthesia ; Anesthesia, General ; Diabetes Insipidus, Neurogenic ; Polyuria*

Diabetes Insipidus, Neurogenic ; diagnosis ; metabolism ; Humans ; Pituitary Neoplasms ; diagnosis ; secondary

Ischemic necrosis of the pituitary gland, known as Sheehan's syndrome, can develop after massive postpartum bleeding. This condition is rarely accompanied by diabetes insipidus. An empty sella is a constant feature of Sheehan's syndrome in the later phase, but very few observations of magnetic resonance imaging (MRI) features in the acute phase are available. We report a case of Sheehan's syndrome presenting with diabetes insipidus leading to severe hypernatremia, showing hemorrhagic postpartum pituitary apoplexy on acute MRI.
Diabetes Insipidus ; Diabetes Insipidus, Neurogenic ; Hemorrhage ; Hypernatremia ; Hypopituitarism ; Magnetic Resonance Imaging ; Necrosis ; Pituitary Apoplexy ; Pituitary Gland ; Postpartum Period

Diabetic insipidus may first present before, during or immediately after pregnancy. Pregnancy serves as a physiologic provocation test that unmasks latent diabetes insipidus. It may explain the very rare first occurrence of diabetes insipidus in the pureperium. Central diabetes insipidus occurring after delivery associated with a catastrophic delivery and postpartum hypopituitarism is more frequent entity. We recently experienced central diabetes insipidus patient, aggrevated polyuria and polydipsia after total hysterectomy due to cervical carcinoma, who had interesting past history of severe polyuria and polydipsia developed during puerperium of 1st pregnancy, 14 years ago. She have had quiet normal pregnancy and there was no definite postpartum complication of pregnancy at that time. There were no change of polyuria and polydipsia during and after second pregnancy and 2 another pregnancy terminated artificially compare to puerperium of 1st delivery. She has intact anterior pituitary gland functinally and anatomically, but the posterior pituitary hyperintense signal with pre-enhance Tl-weighted imaging was absent on MRI.
Diabetes Insipidus ; Diabetes Insipidus, Neurogenic* ; Humans ; Hypopituitarism ; Hysterectomy ; Magnetic Resonance Imaging ; Pituitary Gland, Anterior ; Polydipsia ; Polyuria ; Postpartum Period* ; Pregnancy

Diabetes insipidus is an unusual cause of urinary frequency during pregnancy. It occurs in 2 to 6 per 100,000 pregnancies. It is a disorder in which the abnormal secretion, degradation, or activity of vasopressin cause hypotonic polyuria, polydipsia, and dehydration. And this syndrome appears to be associated with multiple gestations, preeclampsia, and abnormal liver function. We report two cases of pregnancies complicated with diabetes insipidus. One patient was diagnosed during pregnancy and DDAVP (L-deamino-8-d-arginine vasopressin) was used to manage diabetes insipidus. The other patient was diagnosed before pregnancy and DDAVP was not used.
Deamino Arginine Vasopressin ; Dehydration ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic* ; Humans ; Liver ; Polydipsia ; Polyuria ; Pre-Eclampsia ; Pregnancy* ; Vasopressins

Morphea, localized scleroderma, is a connective tissue disease characterized by localized, circumscribed sclerotic patches, or plaques of the skin. The pathogenesis of morphea is still unclear. Central diabetes insipidus is a disease characterized by excessive thirst and urination. In more than half of the cases of central diabetes insipidus, the etiology is still unknown. We experienced the case of morphea and verruca plana in a 32-year old female with a history of central diabetes insipidus. Central diabetes insipidus might have influenced disrupting the homeostasis of the endocrine or immune environment. In the state of disrupted homeostasis, there might be an increased chance for morphea and disseminated verruca plana to develop easily. Based on this, we suppose the possible mechanism about the morphea and disseminated verruca plana developed in central diabetes insipidus.
Connective Tissue Diseases ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic ; Female ; Homeostasis ; Humans ; Scleroderma, Localized ; Skin ; Thirst ; Urination ; Warts

Morphea, localized scleroderma, is a connective tissue disease characterized by localized, circumscribed sclerotic patches, or plaques of the skin. The pathogenesis of morphea is still unclear. Central diabetes insipidus is a disease characterized by excessive thirst and urination. In more than half of the cases of central diabetes insipidus, the etiology is still unknown. We experienced the case of morphea and verruca plana in a 32-year old female with a history of central diabetes insipidus. Central diabetes insipidus might have influenced disrupting the homeostasis of the endocrine or immune environment. In the state of disrupted homeostasis, there might be an increased chance for morphea and disseminated verruca plana to develop easily. Based on this, we suppose the possible mechanism about the morphea and disseminated verruca plana developed in central diabetes insipidus.
Connective Tissue Diseases ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic ; Female ; Homeostasis ; Humans ; Scleroderma, Localized ; Skin ; Thirst ; Urination ; Warts

Diabetes insipidus is a disorder caused by complete or partial deficiency or unresponsiveness to antidiuretic hormone. Both diabetes mellitus and diabetes insipidus are well-known causes of polyuria and polydipsia. Although Wolfram Syndrome, which is characterized by the concurrence of diabetes mellitus and diabetes insipidus along with optic atrophy and ataxia, is frequently reported, the concurrence of diabetes insipidus and type 2 diabetes mellitus without optic atrophy and deafness is rare. We report a 31-year-old woman presenting with hyperglycemic hyperosmolar syndrome caused by type 2 diabetes mellitus complicated with concurrent central diabetes insipidus.
Adult ; Ataxia ; Deafness ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic ; Diabetes Mellitus ; Diabetes Mellitus, Type 2 ; Female ; Humans ; Hyperglycemia ; Optic Atrophy ; Polycystic Ovary Syndrome ; Polydipsia ; Polyuria ; Wolfram Syndrome

Diabetes insipidus is a disorder caused by complete or partial deficiency or unresponsiveness to antidiuretic hormone. Both diabetes mellitus and diabetes insipidus are well-known causes of polyuria and polydipsia. Although Wolfram Syndrome, which is characterized by the concurrence of diabetes mellitus and diabetes insipidus along with optic atrophy and ataxia, is frequently reported, the concurrence of diabetes insipidus and type 2 diabetes mellitus without optic atrophy and deafness is rare. We report a 31-year-old woman presenting with hyperglycemic hyperosmolar syndrome caused by type 2 diabetes mellitus complicated with concurrent central diabetes insipidus.
Adult ; Ataxia ; Deafness ; Diabetes Insipidus ; Diabetes Insipidus, Neurogenic ; Diabetes Mellitus ; Diabetes Mellitus, Type 2 ; Female ; Humans ; Hyperglycemia ; Optic Atrophy ; Polycystic Ovary Syndrome ; Polydipsia ; Polyuria ; Wolfram Syndrome