With regard to biopathology, diabetes- induced foot ulcers caused by nerve pathology and artery and vessel lesions. The foot’s lesions was often easy to treat because they were small and secondly surinfection. The nerve pathology caused deformation and sensation disorders. The ulcer’s position arranged in gradual decreased order: fingers, skin area opposite the tip of foot bone, middle area of foot and heel. S.aureus and Streptococcus sp. were the two most common bacteria in surface infections. Inversely, in deep infections, bacteria often changed and combined strains. Local care had an important role in the treatment.
Diabetes Complications ; Foot Ulcer ; Clinical Medicine ; Diagnosis

Deafness ; Diabetes Complications ; diagnosis ; epidemiology ; Diabetes Mellitus ; epidemiology ; Hearing Loss ; diagnosis ; etiology ; Humans

Artificial intelligence is expected to be applied to various fields in industry and is also introducing a new era in the field of medicine. Artificial intelligence, which is called machine learning or deep learning, analyzes big data, identifies patterns, and performs a task according to an analysis result or pattern. In the medical field, artificial intelligence could be used for such things as disease diagnosis, prediction of complications, or correction of user behavior using big digital data collected from many sources and populations across the world. For diabetes, various studies to predict glycemic response or diabetic complications or to calculate insulin dose are being carried out. In the new era of artificial intelligence, diabetologists need to use the new system to obtain information more actively, explain it to patients in more detail, and support them based on evidence and data.
Artificial Intelligence* ; Diabetes Complications ; Diagnosis ; Humans ; Insulin ; Learning ; Machine Learning

No abstract available.
Colitis/*complications/virology ; Cytomegalovirus Infections/*complications/diagnosis ; *Diabetes Complications ; Humans ; Male ; Middle Aged

Diabetes Mellitus, Type 2 ; complications ; diagnosis ; therapy ; Humans ; Liver Diseases ; complications ; diagnosis ; therapy

Glucokinase maturity-onset diabetes of the young (GCK-MODY) represents a distinct subgroup of MODY that does not require hyperglycemia-lowering treatment and has very few diabetes-related complications. Three patients from two families who presented with clinical signs of GCK-MODY were evaluated. Whole-exome sequencing was performed and the effects of the identified mutations were assessed using bioinformatics tools, such as PolyPhen-2, SIFT, and in silico modeling. We identified two mutations: p.Leu30Pro and p.Ser383Leu. In silico analyses predicted that these mutations result in structural conformational changes, protein destabilization, and thermal instability. Our findings may inform future GCK-MODY diagnosis; furthermore, the two mutations detected in two Korean families with GCK-MODY improve our understanding of the genetic basis of the disease.
Computational Biology ; Computer Simulation ; Diabetes Complications ; Diabetes Mellitus, Type 2* ; Diagnosis ; Glucokinase* ; Humans

Diagnosis and management of chronic complications is very important in diabetes mellitus. In asymptomatic patients, routine screening for chronic diabetic complications is recommended. If not recognized and if preventive care is not implemented, patients are at risk of damage to major organ systems. Tests for diabetic complications vary depending on the type of complications. Some tests require skilled workers and advanced facilities. Many simple screening tests for complications can also be carried out in outpatient clinics. Performing screening tests for complications in outpatient clinics could contribute to timely diagnosis and management of diabetic complications.
Ambulatory Care Facilities ; Diabetes Complications* ; Diabetes Mellitus ; Diagnosis ; Humans ; Mass Screening ; Outpatients*

Spontaneous muscle infarction in diabetic patients is a rare condition that usually occurs in those with advanced diabetic complications. Increased clinical awareness is important for early recognition, particularly in a diabetic patient presenting with a painful thigh or leg swelling. However, the disorder has received little attention in the rehabilitation medicine literature. Magnetic resonance imaging is the diagnostic choice of study, and in the appropriate clinical setting, may obviate the need for a muscle biopsy. We reported three patients with diabetic muscle infarction, review additional reported cases, and discussed the principles of diagnosis and management.
Biopsy ; Diabetes Complications ; Diabetes Mellitus ; Diagnosis ; Humans ; Infarction* ; Leg ; Magnetic Resonance Imaging ; Rehabilitation ; Thigh

BACKGROUND: This study was aimed to investigate the diagnosis-related characteristics of the microvascular complications among patients with type 2 diabetes mellitus and to identify the relationship ship between regular check-up and detection of complications of diabetes. METHODS: The study subjects were 63 patients with diabetic microvascular complications. The data were collected with self-administered questionnaire and analyzed with descriptive statistics. RESULTS: The main motive to identify retinopathy was through 'visiting hospital after having symptoms (58.9%)', and not through regular checkup. The most common symptom of retinopathy was dim dye (84.3%) and the mean duration after diabetes mellitus diagnosis was 6.8 years. The main motive to identify renal complications was through 'visiting hospital after having symptoms and checking for other complications (28.0%)'. The most common symptom of renal complications was edema of face and hands (72.0%) and the mean duration following diabetes mellitus diagnosis was 8.4 years. The main motive to identify neuropathy was through 'visiting hospital after having symptoms (34.8%)', and not regular checkup. The most common symptom of neuropathy was tingling sensation of feet (100.0%) and the mean duration following diabetes mellitus diagnosis was 7.4 years. CONCLUSION: Based on the results, we suggest that diabetes complications check-up should be performed simultaneously to make the diagnosis of diabetes mellitus, and that the health care providers could provide them with more opportunities to have such check-ups with standardized complications care guidelines.
Diabetes Complications ; Diabetes Mellitus ; Diabetes Mellitus, Type 2* ; Diagnosis ; Edema ; Foot ; Hand ; Health Personnel ; Humans ; Sensation ; Ships ; Surveys and Questionnaires

Aged ; Animals ; Diabetes Complications ; Diagnosis, Differential ; Female ; Humans ; Ophthalmoplegia ; diagnosis ; etiology ; Tolosa-Hunt Syndrome ; diagnosis