3.Biological characteristics of IL-24 and mechanisms of its anti-tumor action
Journal of International Oncology 2010;37(9):657-661
Studies have shown that IL-24 is the only cytokine capable of inhibiting tumor growth and neovascularization as well as stimulating immune system. IL-24 exerts its inhibition effects through pathways independent of p53, Rb, p16 and other tumor suppressor genes and has no effect on normal cells. IL-24 has emerged as a hot topic in cancer therapy research.
4.Pay attention to the adaptive immune regulation and relevant biological phenomena in gastrointestinal disorders.
Chinese Journal of Pediatrics 2012;50(8):561-562
Adaptive Immunity
;
Bacterial Infections
;
immunology
;
prevention & control
;
Biological Evolution
;
Epithelial Cells
;
immunology
;
Gastrointestinal Diseases
;
immunology
;
prevention & control
;
Humans
;
Immunity, Innate
;
Lymphocytes
;
immunology
;
Mucous Membrane
;
cytology
;
immunology
;
Receptors, Pattern Recognition
;
immunology
;
Toll-Like Receptors
;
immunology
6.RDAWA-based reader-driven acquisition of library holdings
Haixia XU ; Yingxia XU ; Di WU
Chinese Journal of Medical Library and Information Science 2015;(2):67-70
A collective intelligent perception-supported and RDAWA-based reader-driven acquisition model of li-brary holdings was proposed with the development of academic library holdings as its background .The design ideas of RDAWA were described , the master framework of RDAWA was analyzed , the considerations in design of RDAWA that simplified the input procedure and met the reading requirements of readers were elaborated with the biblio-graphic information database , data analysis module and acquisition order generation algorithm summarized .
9.Cloning of Plasmodium fiddpmon from Hainan Province in China and Its Characteristics
Di XU ; Weibin GNAN ; Fengyi QU
Academic Journal of Second Military Medical University 1982;0(01):-
Two isolates of Plasmodium jalcipanm from Hainan Province were cloned by limiting dilution method and eight clones were established. Some characteristics including drug sensitivity and antigenicity of these clones were observed. The results showed that the established clones were different from each other in chloroquine sensitivity and antigenicity. The ID50 of chloroquin3e against 6 clones from isolate Fcc-7801 varied between 60.60 and 13.08 nmol/L The ID50 of chloroquine against 2 clones from isolate Fcc-1 were 93.63 and 49.64 nmol/L, respectively. According to the indirect fluorescent antibody (IFA) Teactivity of these clones with a panal of murine anti-gpl95 McAbs, 8 clones could be divided into 5-serotypes, 3 of which were consistent with the Ⅴ , Ⅵ, Ⅶ serotypes devided by J. S. McBride (1985).
10.Usefulness of the myocardial performance index for assessing right ventricular function in patients with atrial septal defect
Jiandong DING ; Fengxiang LU ; Di XU
Chinese Journal of Ultrasonography 2003;0(11):-
Objective To determine the clinical value of myocardial performance index (MPI) in the assessment of right ventricular function in the patients with atrial septal defect (ASD). Methods The study included 23 patients with ASD and 81 normal subjects. MPI, defined as the sum of isovolumic relaxation time and isovolumic contraction time derived by ejection time, was measured from tricupid inflow and right ventricular outflow Doppler velocity profiles recorded during routine echocardiography. Results ①The isovolumic relaxation and isovolumic contraction times [respectively ( 74.78 ? 13.86 )ms vs ( 60.93 ? 12.94 )ms, P