OBJECTIVE:To analyze the clinical effects of Orion anterior plate combined with titanium mesh and bone graft in the treatment of unstable cervical spondylosis METHODS:The databases of PubMed and Wanfang were retrieved using search terms of"cervical vertebrae,Orion anterior plate,titanium mesh,and spinal fusion"both in English and Chinese for documents concerning Orion anterior plate combined with tltanium mesh and bone graft in the treatment of unstable cervical spondylosis.The literatures published between 1990 and 2008were selected.The repetitive studies were excluded.A total of 54 documents were searched by computer,and 13 papers were included in the final analysis according to inclusive criteria RESULTS:By the application of Orion anterior plate combined with titanium mesh and bone graft in the treatment of unstable cervical spondylosis,the cervical curvature and stability could be restored,the intervertebral height would be maintained and the implanted bone could get fusion easily.The injury and complications caused by auto-ilium graft could be avoided.In addition,the locking cervical plate could effectively prevent damage caused by spondylolisthesis,and strengthened the cervical stability.It is a good method for anterior internal fixation of cervical vertebrae CONCLUSION:It is an ideal method to treat unstable cervical spondylosis by using Orion anterior plate combined with titanium mesh and bone graft .