1.Combination of cryopreserved hydroxyapatite/bone marrow mesenchymal stem cells repairs rabbit radial defects
Zhiyuan XING ; Jibo ZHANG ; Lingju KONG ; Jiansheng LIU ; Deyu ZHENG
Chinese Journal of Tissue Engineering Research 2013;(25):4629-4636
10.3969/j.issn.2095-4344.2013.25.010
2.Effects of long-term walking exercise on health status of low labor-intensity people
Hu LI ; Baicheng WANG ; Ke TAO ; Hongjun LIU ; Xingwei XIE ; Deyu LI ; Lingwei KONG
Journal of Chinese Physician 2018;20(3):342-346
Objective To investigate the effect of long-term walking exercise on the health status of low-labor-intensity population under long-term walking exercise.Methods A total of 100 volunteer teachers from universities in Beijing were enrolled.After physical examination,they were randomly divided into control group and observation group.The observation group regularly carried out corresponding encouragingactivities and recorded the daily number of steps.The corresponding indexes were measured again after 450 days.Results 45.24% participants in the observation group got more than 75% participation rate.The lower the participation rate,the lower the average daily steps (P < 0.05).The fasting blood glucose,systolic blood pressure,LDL and total cholesterol were lower than other groups in the group participation rate <25% (P <0,05).The body mass index,systolic blood pressure,fasting blood glucose,total cholesterol,ratio diabetes and hypertension in low activities group (< 7 500 steps/day) were lower than those in other groups (P < 0.05).Conclusions Walking exercise can achieve good long-term persistence with constant feedback.For those who are older and whose initial indicators are higher,participation rate and exercise volume are more likely to be better under the guidance of encouragement.Persisting long-term walking exercise can help reduce blood pressure and blood lipids.
3.Clinical study of anterior controllable antedisplacement and fusion for the treatment of cervical ossification of posterior longitudinal ligament
Jiangang SHI ; Jingchuan SUN ; Yongfei GUO ; Haisong YANG ; Ximing XU ; Yuan WANG ; Yingjie WANG ; Qingjie KONG ; Shengyuan ZHOU ; Guodong SHI ; Guohua XU ; Deyu CHEN ; Xiongsheng CHEN ; Wen YUAN ; Lianshun JIA
Chinese Journal of Orthopaedics 2018;38(15):919-926
Objective To investigate the clinical effect of anterior controllable antedisplacement and fusion (ACAF) for the treatment of ossification of the posterior longitudinal ligament (OPLL) of the cervical spine.Methods The data of 45 cases with cervical posterior longitudinal ligament ossification treated by ACAF from March 2017 to October 2017 were retrospectively analyzed,including 25 males and 20 females,age 45-68 years,average 57.5 years.There were 18 cases involving C3 vertebral body,30 cases involving C4 vertebral body,40 cases involving C5 vertebral body,34 cases involving C6 vertebral body,and 7 cases involving C7 vertebral body.The function of the neural function was evaluated by the Japanese Orthopaedic Association (JOA) scoring system at preoperation and latest follow-up.The curvature of the cervical spine was measured on the lateral X-ray film of the cervical spine,the maximum occupying ratio of the spinal canal was measured on the cross section of the CT scan,and compression of the cervical spinal cord was evaluated by the cervical MRI.Results Patients were followed up for 3 to 6 months (average,3.9 months).The improvement of neurological function was obtained in all the patients.The JOA score improvement rate at the latest follow-up was 71.3%±9.6%.The cervical lordosis was improved from preoperative 4.5°±3.8° to 10.3°±4.8° at the latest follow-up.The canal stenosis ratio was decreased from preoperative 54.3%±8.2% to 12.5%±5.3% at the latest follow-up.MRI showed that the cervical spinal cord was adequately decompressed in situ.No specific complications were identified that were associated with this technique.Conclusion The present study elaborates the surgical tips and demonstrates the satisfactory outcome of ACAF for the treatment of OPLL.This novel technique has the potential to serve as an alternative surgical technique for the treatment of cervical OPLL.
4.A Three-Month Non-Interventional Study of Asthma Treatment with Budesonide/Formoterol
Xin ZHOU ; Jianguo HONG ; Jianbao XIN ; Changgui WU ; Jianping BO ; Tiantuo ZHANG ; Changzheng WANG ; Shaoxi CAI ; Chan LIU ; Chea QIU ; Jianan HUANG ; Guoxiang LAI ; Lingfei KONG ; Chuntao LIU ; Zhaang MA ; Kewu HUANG ; Heping FANG ; Jianying ZHOU ; Zhuochang CHENG ; Peizong SUN ; Genyun SUN ; Libo WANG ; Suping TANG ; Zhimia CHEN ; Changchong LI ; Deyu ZHAO ; Rongjun LIN ; Yuefie ZHENG ; Li XIANG ; Xiaoqing ZHOU ; Yuzhi CHENG
Chinese Journal of Respiratory and Critical Care Medicine 2009;8(4):341-344
Objective To evaluate the efficacy of Budesonide/formoterol to control asthma under real-life conditions.Methods A muhi-center, open label, non-interventional study was conducted.Asthma control after 12 week therapy with Budesonide/formoterol was assessed by Asthma Control Questionnaire (ACQ) and modified Asthma Control Questionnaire (ACQ5).Results A total of 360 asthma patients were recruited,including 228 adult patients and 132 child patients.After 12 weeks' therapy,all the patients' medium value of ACQ was decreased significantly from 2.03 (adults 2.20, children 1.74) at baseline to 0.60 (adults 0.78, children 0.29) (P < 0.0001), and the medium value of ACQ5 was also decreased significantly from 2.4 (adults 2.24, children 1.76) at baseline to 0.47 (adults 0.62, children 0.20) (P < 0.0001).Conclusion Budesonide/formoterol is effective in asthma treatment, by which most asthma patients obtain and maintain clineal control.
5.Distribution of Traditional Chinese Medicine Patterns and Analysis of Factors Related to Acute Exacerbation in Group E of Chronic Obstructive Pulmonary Disease
Xiaoning LI ; Mingzhe CHEN ; Xurui HUANG ; Ping'an ZHANG ; Deyu KONG ; Xudong ZHENG ; Liangduo JIANG ; Jianjun WU
Journal of Traditional Chinese Medicine 2023;64(17):1786-1791
ObjectiveTo analyze the distribution of traditional Chinese medicine (TCM) patterns as well as factors related to acute exacerbation in group E of chronic obstructive pulmonary disease (COPD). MethodsThe general data of 161 COPD patients, including gender, age, body mass index (BMI), disease course, smoking history, and past history, were collected. In terms of the four examinations of TCM, the differentiated patterns included phlegm-heat obstructing the lung, turbid phlegm obstructing the lung, phlegm stasis obstructing the lung, lung-spleen qi deficiency, and lung-kidney deficiency. The modified British Medical Research Council (mMRC) scale and COPD assessment test (CAT), the pulmonary function indicators including forced expiratory volume in the first second (FEV1) and ratio of forced expiratory volume to forced vital capacity at second 1 (FEV1/FVC), GOLD grade, and the patient's acute exacerbations in the previous year were recorded. Multivariate regression analysis was performed using logistic regression model to determine the relevant factors of patients in COPD group E. The distribution of acute exacerbations in different TCM symptom patients in group E was analyzed. ResultsThere were 80 patients (49.69%) in group E and 81 patients (50.31%) in non-group E. In group E, 23 (28.75%) patients had a history of two acute exacerbations, while 35 (43.75%) had three acute exacerbations, and 22 (27.5%) had more than three acute exacerbations. There were 13 (16.25%) cases of phlegm-heat obstructing the lung pattern, 6 (7.5%) cases of turbid phlegm obstructing the lung pattern, 8 (10%) cases of phlegm stasis obstructing the lung pattern, 22 cases (27.5%) of lung-spleen qi deficiency pattern, and 31 (38.75%) cases of lung-kidney deficiency pattern. There were significant differences in smoking history, disease course, TCM pattern, TCM syndrome score, mMRC score, and CAT score between groups (P<0.05). A total of 107 of the 161 patients completed pulmonary function tests, and the differences in FEV1, FEV1/FVC and GOLD grades between groups were statistically significant (P<0.05). Multivariate regression analysis showed that TCM pattern, TCM syndrome score and CAT score were statistically significant factors for COPD patients in group E (P<0.05). There were statistically significant differences in the number of acute exacerbations in different TCM patterns in group E (P<0.05). The patients with two acute exacerbations in the past year were mainly phlegm-heat obstructing the lung and lung-spleen qi deficiency patterns, while the three acute exacerbations were mainly seen in lung-spleen qi deficiency and lung-kidney deficiency patterns, and more than three exacerbations were more common with lung -kidney deficiency pattern. ConclusionsPatients in COPD group E were mainly the lung-spleen qi deficiency and lung-kidney deficiency patterns. Deficiency of healthy qi is the main reason for the increase in the number of acute exacerbations, and TCM patterns and CAT score were the main related factors.