1.Nodular Pigmented Villonodular Synovitis of the Right Shoulder Joint: One Case Report
Kee Byoung LEE ; Jin Young LEE ; Deuk Sun SHIN
The Journal of the Korean Orthopaedic Association 1989;24(3):988-992
In 1941, Jaffe and coworkers studied a lesion with histologic appearance of fibrous stroma, pigmented deposition and histiocytic infiltration as well as giant cell, for which they named pigmented villonodular synovitis, bursitis and tenosynovitis. Thereafter many authors have discussed etiology, clinical and radiological features, pathology and treatment regarding the disease. Almost all, this disease is monoarticular and knee joint is most common site. We experienced a case of localized pigmented villonodular synovitis involving an shoulder joint which was treated by local excision and obtained good result.
Bursitis
;
Giant Cells
;
Knee Joint
;
Pathology
;
Shoulder Joint
;
Shoulder
;
Synovitis, Pigmented Villonodular
;
Tenosynovitis
2.Prevalence of hepatitis C virus antibody in korea.
Hak Kyoon SHIN ; Jae Deuk YOON ; Jae Chang YOO ; Moon Bo KIM ; Ki Soon KIM ; Sun Duck SUH
Journal of the Korean Society of Virology 1993;23(2):203-214
No abstract available.
Hepacivirus*
;
Hepatitis C*
;
Hepatitis*
;
Korea*
;
Prevalence*
3.Interleukin-1 beta production by monocytes from leprosy patients.
In Hong CHOI ; Jeon Soo SHIN ; Sun Kyung PARK ; Sang Nae CHO ; Joo Deuk KIM ; Se Jong KIM
Yonsei Medical Journal 1990;31(4):301-307
The cause responsible for the lack of an efficient cell-mediated immunity or a delayed type hypersensitivity to M. leprae in lepromatous patients is poorly understood. But the resistance to M. leprae infection in humans is likely mediated by the activated macrophages to present M. leprae antigen to T cells for cell-mediated immunity. Phenolic glycolipid-I (PGL-I) is a M. leprae-specific antigen and is supposed to play a significant role in the long lasting unresponsiveness in lepromatous leprosy. In this study, IL-1 activities were tested among leprosy patients to evaluate monocyte function and the role of IL-1 in the immunosuppression in leprosy. We found that peripheral blood mononuclear cells (PBMCs) from tuberculoid patients were strongly reactive to M. leprae (mean cpm; 28,853 +/- 28,916), but the proliferative responses of PBMCs from lepromatous patients (mean cpm; 6,051 +/- 803) were significantly lower. IL-1 concentration in culture supernatant of monocytes from lepromatous patients was similar to that from tuberculoid patients with stimulation of M. leprae (lepromatous: 1,014 +/- 637 pg/ml, tuberculoid: 1,012 +/- 167 pg/ml) or lipopolysaccharides (IPS) (lepromatous: 3,479 +/- 2,188 pg/ml, tuberculoid: 4,246 +/- 2,432 pg/ml). The IL-1 concentration is sera from lepromatous patients (42 +/- 30 pg/ml) tended to be higher than those from tuberculoid patients (28 +/- 69 pg/ml). And there was no significant difference in IL-1 production between peritoneal macrophages from mice sensitized with PGL-1 and those from nonsensitized mice. In conclusion, this study suggests that the immunosuppression in lepromatous patients may not be due to the decreased production of IL-1. And the increased IL-1 activity in sera may affect the inflammatory response of lepromatous patients.
Glycolipids/pharmacology
;
Human
;
Immunity, Cellular
;
Interleukin-1/*biosynthesis
;
Leprosy, Lepromatous/blood/*metabolism
;
Lymphocyte Activation
;
Monocytes/*metabolism
;
Mycobacterium leprae/metabolism
;
Support, Non-U.S. Gov't
4.Production and characterization of monoclonal antibodies to borrelia burgdorferi, the lyme disease agent.
Jeon Soo SHIN ; Sang Nae CHO ; Jung Lim LEE ; Sun PARK ; Kyeong Han YOON ; Jae Myun LEE ; Mi Kyeong LEE ; Se Jong KIM ; Joo Deuk KIM
Journal of the Korean Society for Microbiology 1992;27(6):537-544
No abstract available.
Antibodies, Monoclonal*
;
Borrelia burgdorferi*
;
Borrelia*
;
Lyme Disease*
5.Prevalence of hepatitis E virus antibody on residents of seashore town in Korea.
Hak Kyoon SHIN ; Jae Deuk YOON ; Jae Chang YOO ; Moon Bo KIM ; Ki Soon KIM ; Sun Duck SUH ; Jung Suh KIM
Journal of the Korean Society of Virology 1993;23(2):215-222
No abstract available.
Hepatitis E virus*
;
Hepatitis E*
;
Hepatitis*
;
Korea*
;
Prevalence*
6.Prevalence of Masked Hypertension: a Population-Based Survey in a Large City by Using 24-Hour Ambulatory Blood Pressure Monitoring.
Moo Yong RHEE ; Sun Woong KIM ; Eun Hee CHOI ; Ji Hyun KIM ; Deuk Young NAH ; Sung Joon SHIN ; Namyi GU
Korean Circulation Journal 2016;46(5):681-687
BACKGROUND AND OBJECTIVES: We estimated the prevalence of hypertension and hypertension subtypes in a large semi-urban city in Korea, using 24-hour ambulatory blood pressure monitoring (ABPM) in a randomly selected sample population. SUBJECTS AND METHODS: A random sample (aged 20-65 years) from a city with an adult population of approximately 600000 was selected by using a list-assisted random digit dialing method. The 24-hour ABPM and conventional blood pressure measurement (CBPM) of these individuals were obtained. RESULTS: Among the 496 participants, valid 24-hour ABPM and CBPM were obtained from 462 (93%) individuals. The estimated prevalence of hypertension in Goyang was 17.54% by CBPM and 32.70% by 24-hour ABPM (p<0.01). In the age stratified analysis, both CBPM and 24-hour ABPM showed increased prevalence of hypertension with age. The estimated prevalence of masked hypertension was 16.22% and that of white-coat hypertension was 1.08%. Men had a higher prevalence of masked hypertension than women (20.79% vs. 11.86%, p=0.0295). The estimated prevalence of masked hypertension was 17.5%, 20.58%, 24.34%, and 13.29% in the age categories of 30s, 40s, 50s, and 60s, respectively. The estimated prevalence of masked uncontrolled hypertension was 26.79% in patients with hypertension who were taking antihypertensive medications. CONCLUSION: The estimated prevalence of hypertension by 24-hour ABPM was higher than that by CBPM, revealing high prevalence of masked hypertension. The high prevalence of masked hypertension supports the adoption of ABPM in the national population survey and clinical practice to improve public health and reduce health care costs.
Adult
;
Blood Pressure
;
Blood Pressure Monitoring, Ambulatory*
;
Female
;
Health Care Costs
;
Humans
;
Hypertension
;
Korea
;
Male
;
Masked Hypertension*
;
Masks*
;
Methods
;
Prevalence*
;
Public Health
7.Is a Decreased Serum Testosterone Level a Risk Factor for Prostate Cancer? A Cohort Study of Korean Men.
Bo Sung SHIN ; Eu Chang HWANG ; Chang Min IM ; Sun ouck KIM ; Seung Il JUNG ; Taek Won KANG ; Dong Deuk KWON ; Kwangsung PARK ; Soo Bang RYU
Korean Journal of Urology 2010;51(12):819-823
PURPOSE: To investigate patients who had transrectal ultrasonography (TRUS)-guided prostate biopsy to define the role of the serum testosterone level in predicting prostate cancer risk and its association with a high Gleason score. MATERIALS AND METHODS: A total of 568 patients who underwent prostate biopsy were entered in this study. We divided the patients into two groups according to serum testosterone level (median level, 3.85 ng/ml): the high-testosterone group (n=285) and the low-testosterone group (n=283). Multivariate regression analysis was used to define the effect of age, prostate volume, serum prostate-specific antigen (PSA) level and PSA density, and serum testosterone level on the risk of prostate cancer and a high Gleason score. RESULTS: Baseline characteristics did not differ significantly between the two groups. Compared with the high-testosterone group, the low-testosterone group had a significantly higher prostate cancer incidence (38.9% vs. 29.5%, p=0.018). Factors associated with an increased risk of prostate cancer were increased age (odds ratio [OR]=1.08, 95% confidence interval [CI]=1.25-3.16, p=0.001), a high serum PSA level (OR=3.35, 95% CI=2.63-4.25, p=0.001), a low prostate volume (OR=0.183, 95% CI=0.11-0.30, p=0.001), and a low serum testosterone level (OR=1.99, 95% CI=1.25-3.16, p=0.001). Among these, only the serum PSA level was a strong predictor of high-grade prostate cancer (Gleason score > or =7) (OR=2.19, 95% CI=1.57-2.95, p=0.001). CONCLUSIONS: Patients with lower levels of serum testosterone had a higher risk of prostate cancer than did patients with high serum testosterone. Even though a lower serum testosterone level was a predictor of prostate cancer risk, it was not associated with an increased risk of high-grade prostate cancer.
Biopsy
;
Cohort Studies
;
Humans
;
Incidence
;
Male
;
Prostate
;
Prostate-Specific Antigen
;
Prostatic Neoplasms
;
Risk Factors
;
Testosterone
8.Clinical Usefulness of GFR Measurement Using Tc-99m DTPA Renal Scan in Kidney Transplantation Patients.
Bok Gyu GAM ; Yong Hoon SHIN ; Yong Ki PARK ; Dae Hyun YUN ; Ik Deuk JANG ; Mi Sun KIM ; Joong Kyung KIM ; Meung Soon YUN ; Shi Rae LEE
Korean Journal of Nephrology 1999;18(1):168-174
In clinical practice, Tc-99m DTPA renal scan has been using for screening for the presence of renal dysfunction to determine the need for early treatment in kidney transplantation patients. We measured glomerular filtration rate(GFR) using Gates method during the routine Tc-99m DTPA renal scan, predicted creatinine clearance estimated by Cockcroft and Gault formula and 24-hour creatinine clearance and compared each other in 88 kidney transplantation patients simultaneously. The range of renal uptake(%) of Tc-99m DTPA was from 1.8% to 10.4% and the correlation between 24-hour creatinine clearance and renal uptake showed Y=7.176X8.975Y=creatinine clearance(ml/min), X=renal uptake(%) and the correlation coefficient was 0.771. The correlation coefficient between GFR (ml/min) using Tc-99m DTPA renal scan and predicted creatinine clearance was 0.765. The correlation coefficient between predicted creatinine clearance and 24-hour creatinine clearance was 0.850. We concluded that the measurement of GFR using Tc-99m DTPA renal scan was clinically useful in kidney transplantation patients with the advantage of simplicity, low expense, opportunity for renal imaging.
Creatinine
;
Filtration
;
Humans
;
Kidney Transplantation*
;
Kidney*
;
Mass Screening
;
Pentetic Acid*
9.Leukemoid Reaction, a Rare Paraneoplastic Syndrome in Urothelial Cell Carcinoma: Is It an Indicator of a Poor Prognosis?.
Ho Seok CHUNG ; Bo Sung SHIN ; Ho Song YU ; Eu Chang HWANG ; Sun Ouck KIM ; Sung Il JUNG ; Taek Won KANG ; Dong Deuk KWON ; Kwangsung PARK
Korean Journal of Urological Oncology 2015;13(3):134-137
A leukemoid reaction is usually associated with malignancies of the lung, stomach, and thyroid. In contrast, urothelial cell carcinoma is rarely associated with leukemoid reactions, with few cases reported over the past 30 years. Here, we describe a patient with urothelial cell carcinoma who exhibited a leukemoid reaction. The patient had an elevated white blood cell count and experienced a rapid and aggressive clinical course, terminating in death. For urothelial cell carcinoma patients exhibiting a leukemoid reaction, removal of the inciting tumor is the definitive treatment. However, considering the aggressive nature of these tumors, if the patient is unsuitable for radical surgical management, palliative chemotherapy should be considered.
Drug Therapy
;
Humans
;
Leukemoid Reaction*
;
Leukocyte Count
;
Lung
;
Paraneoplastic Syndromes*
;
Prognosis*
;
Stomach
;
Thyroid Gland
10.The Accuracy of Noncontrast Helical Computerized Tomography Versus Intravenous Pyelography in Patients with Suspected Acute Urolithiasis in the Emergency Department.
Hyuk Joong CHOI ; Seung Woo KIM ; Shin Deuk LEE ; Tae Soo KIM ; Sae Hoon PARK ; Tai Ho IM ; Sun Il KIM ; Byung Hui KOH
Journal of the Korean Society of Emergency Medicine 2004;15(6):542-547
PURPOSE: This study was performed to compare the accuracy of noncontrast helical computerized tomography (NHCT) with that of intravenous pyelography (IVP) in the evaluation of urolithiasis in the emergency room (ER). METHODS: Between November 2003 and February 2004, a total of 47 consecutive patients presenting to the emergency department with acute flank pain were evaluated with NHCT followed by IVP. The mean of the time interval between NHCT and IVP was less than 5 minutes. All 47 sets of evaluations were later assessed randomly by an independent consulting radiologist for the presence, size, and location of a stone, ureteral dilatation, and secondary signs of ureteral obstruction. RESULTS: Forty-three of the 47 patients were diagnosed with urolithiasis. In 39 of the 43 patients diagnosed with ureteral calculi, the NHCT made the diagnosis. IVP made the diagnosis in 26 of the 43 patients. NHCT had a 90.7% sensitivity, 100% specificity, and 68% accuracy. Compared with IVP, using the McNemar test, NHCT was significantly better able to predict the presence of urolithiasis (p<0.001). CONCLUSIONS: Unnenhanced helical CT is superior to IVP in the demonstration of ureteral calculi in patients with suspected acute urolithiasis in the ER.
Diagnosis
;
Dilatation
;
Emergencies*
;
Emergency Service, Hospital*
;
Flank Pain
;
Humans
;
Sensitivity and Specificity
;
Tomography, Spiral Computed
;
Ureter
;
Ureteral Calculi
;
Ureteral Obstruction
;
Urography*
;
Urolithiasis*