1.Intraoperative neuromonitoring technology in protection of non-recurrent laryngeal nerve
Detao YIN ; Hongqiang LI ; Yongfei WANG ; Zheng LIU ; Meng JIA ; Yayuan ZHANG ; Yang HAN
Chinese Journal of Endocrine Surgery 2016;10(4):294-297
Objective To investigate the application of intraoperative neuromonitoring (IONM) during thyroidectomy for non-recurrent laryngeal nerve (NRLN).Methods From Oct.2013 to Apr.2016,2846 patients underwent thyroidectomy with the application of IONM,and 11 patients with non-recurrent laryngeal nerve were analyzed.Results 11 cases of NRLN were all accurately identified by IONM,and no injury of NRLN occurred during thyroid surgery.Conclusions NRLN is uncommon in clinical and it is difficult to be predicted before surgery and easy to be injured.The application of IONM can reduce the possibility of NRLN injury remarkably.
2.Factors affecting health-related quality of life in patients with Parkinson's disease
Journal of Apoplexy and Nervous Diseases 2023;40(3):253-256
Objective Our objective was to identify factors predicting health-related quality of life (HRQoL) in patients with Parkinson's disease (PD) Methods A cross-sectional study was carried out in 161 PD patients. QoL was assessed with the PDQ-39.Motor symptoms and non-motor symptoms were evaluated by a list of assessment tools including the Hoehn and Yahr scale,The Movement Disorder Society Unified Parkinson Disease Rating Scale et al. The Spearman correlation coefficient r was used to evaluate the correlation between PDQ-39 and motor and non-motor factors. Multiple linear regression models were used to demonstrate whether the factors investigated contribute significantly to QoL. Results PDQ-39 Summary Index was highly correlated with Voice handicap index(r=0.616) and correlated at a moderate level (r=0.30-0.50) with UPDRS-I,UPDRS-II,Parkinson Fatigue Scale,Modified Apathy Evaluation Scale,Geriatric Depression Scale,Gait and Falls Questionnaire,Eating Assessment Tool Scale. Depression,gait,swallowing,voice handicap and gender were independent predictors of HRQoL in the multivariate analysis model. Depression showed to be the most consistent determinant of HRQoL,followed by gait problems,swallowing,voice handicap and gender. Conclusion Depression,gait problems,swallowing,voice handicap and gender are significant factors contributing to a poor quality of life in Parkinson's disease patients. Swallowing and voice handicap,as well as depression,gait problems that are widely recognized,are also factors that cannot be ignored.
3.Advance in Parkinson's disease rehabilitation: a visualization analysis
Manxinyu SHI ; Detao MENG ; Boyan FANG
Chinese Journal of Rehabilitation Theory and Practice 2022;28(9):1060-1064
4.Effect of physical activity levels on risk of Parkinson's disease: a cross-sectional analysis based on China Health and Retirement Longitudinal Study
Jiayu WU ; Detao MENG ; Xiaoxiao LIANG
Chinese Journal of Rehabilitation Theory and Practice 2023;29(10):1135-1139
ObjectiveTo investigate the effect of different levels of physical activity on the risk of Parkinson's disease (PD). MethodsA total of 9 726 subjects from 2018 China Health and Retirement Longitudinal Study (CHARLS) data were analyzed with multivariate Logistic regression analysis. ResultsOf the 9 726 subjects, 188 suffered from PD, with a prevalence of 1.93%. The subjects who aged more than 65 (OR = 2.58, 95%CI 1.74 to 3.96, P < 0.001) and widowed (OR = 1.42, 95%CI 1.01 to 1.99, P = 0.043) were at a higher risk of developing PD. Subjects who engaged in high-intensity physical activities (OR = 0.38, 95%CI 0.27 to 0.54, P < 0.001) were at a lower risk of PD. After adjusting for age and marital status, high-intensity physical activity still reduced the risk of PD (OR = 0.42, 95%CI 0.29 to 0.61, P < 0.001). ConclusionHigh-intensity physical activity (over 3 000 metabolic equivalents a week) may reduce the risk of PD.