We studied the thyroid dysfunction occurrence in the adult people who went through health examinations in Kutchan Kosei General Hospital between April 2, 2007 and March 31, 2008.Enrolled in this study were 1,647 adult men and 1,104 adult women. However, 17 men and 51 women were excluded from the study because they had histories of thyroid diseases.Serum FT3 and FT4 values were lower in women than in men. Likewise, serum TSH values for women were higher than those for men.Hypothyroidism (low serum FT3 and FT4 levels) occurred more frequently in women than in men. More women than men showed serum TSH values over 49.1μU/ml.
Human Females ; Male population group ; Adult ; Serum ; Desiccated thyroid

A rare case of primary squamous cell carcinoma of the thyroid is reported herein. A 64-year-old Malay lady presented with a gradually enlarging thyroid nodule for the past 6 months and underwent total thyroidectomy. Histopathology revealed a squamous cell carcinoma of the thyroid with complete resection. Possible primary tumour elsewhere was excluded. Postoperative irradiation was given and patient is still alive after 2 years of follow-up.
Desiccated thyroid ; Carcinoma, Squamous Cell ; Primary ; Case Report ; Histopathology

The middle thyroid vein has been noted to be frequently absent during thyroidectomies in Papua New Guinea (PNG). To verify this and other known inconsistencies in the neck a total of 103 bodies were dissected at the Port Moresby General Hospital in 2002. The middle thyroid vein was absent in 59% of the cases. It would be to the advantage of surgeons in PNG to be aware of this.
Veins ; Desiccated thyroid ; Papua New Guinea ; Lower case en ; Melanesians

Participants in our screening program for cerebrovascular disease are supposed to receive thyroid checkups at the time of ultrasound imaging of carotid arteries. Thus far, a total of 4,338 people have participated in this program. Of the total, 17 cases of papillary thyroid carcinoma were found (detection ratio: 0.39%). This study concerned with the 13 cases which underwent surgical treatment in our hospital. They all were diagnosed as early cancers--eight cases at stage N0 and five cases at stage N1--with an average tumor diameter of 11 mm. Besides, five cases of Basedow's disease (hyperthyroidism) and 15 cases of chronic thyroiditis were found (detection ratio: 0.35%). Of the 15 chronic thyroiditis cases, nine were found to have symptoms of hypothyroidism. We concluded that our screening program for cerebrovascular disease involving the ultrasonographic scans of the thyroid gland is very helpful not only in detecting malignancies at an early stage but also in screening for functional abnormalities of the thyroid.
Aspects of disease screening ; Ultrasonography ; Desiccated thyroid ; Thyroid Gland ; Diagnostic Neoplasm Staging

Most previous studies on RET and p53 proteins have focused on thyroid papillary carcinoma. We investigated the role of RET and p53 protein expressions using immunohistochemistry on 52 cases of thyroid follicular adenomas and studied the follow-up records of these patients. The range of follow-up period was 3 to 14 years. The patients were between 15 and 71 years of age with a median age of 34.5 years. There were 46 females and 6 males. Except for 3 cases, all patients were Malays. The minimum volume of the tumour was 1000 mm3 and the maximum was 512,000 mm3 with a median of 270,000 mm3. Eleven (21.2%) cases showed RET expression. RET expression was not statistically significant when cross-tabulated against sex (p = 0.322), ethnicity (p = 0.518), age (p = 0.466) and symptom duration (p = 0.144). Six (11.5%) of 52 cases showed p53 immunopositivity. p53 expressions were also not significantly correlated to the clinical parameters above. There was no correlation between RET and p53 protein expressions. The only statistically significant finding was the association of tumour volume with duration of symptoms (p = 0.05). All patients are alive at the time of writing. 3 had recurrent goitre, 2 of these were diagnosed as colloid goitre while the third was a follicular lesion. One patient suffered from depression requiring anti-depressant treatment. In conclusion, unlike papillary carcinoma in which the roles of ret and p53 oncogenes are known, their roles in influencing the behaviour of follicular adenoma has not been ascertained.
Oncogene, RET ; lower case pea ; Desiccated thyroid ; Protein p53 ; Age, NOS