1.Practice Patterns of Allergen Immunotherapy in Korea: Where Are We?.
Allergy, Asthma & Immunology Research 2013;5(5):249-250
No abstract available.
Desensitization, Immunologic
2.Allergen immunotherapy.
Korean Journal of Medicine 2002;62(3):244-249
No absract available.
Desensitization, Immunologic*
6.Successful desensitization of pemetrexed-induced anaphylaxis in a patient with malignant mesothelioma.
Jeonghwan YOUK ; Hyunkyung PARK ; Kwang Nam JIN ; Hyun Jong MOON ; Min Suk YANG ; Ki Hwan KIM ; Jin Soo KIM
The Korean Journal of Internal Medicine 2017;32(3):563-565
No abstract available.
Anaphylaxis*
;
Desensitization, Immunologic
;
Humans
;
Mesothelioma*
;
Pemetrexed
7.Successful desensitization of pemetrexed-induced anaphylaxis in a patient with malignant mesothelioma.
Jeonghwan YOUK ; Hyunkyung PARK ; Kwang Nam JIN ; Hyun Jong MOON ; Min Suk YANG ; Ki Hwan KIM ; Jin Soo KIM
The Korean Journal of Internal Medicine 2017;32(3):563-565
No abstract available.
Anaphylaxis*
;
Desensitization, Immunologic
;
Humans
;
Mesothelioma*
;
Pemetrexed
9.Updates on desensitization for hypersensitivity reactions related to chemotherapy.
Suh Young LEE ; Min Suk YANG ; Jae Woo JUNG ; Mi Jung OH ; Chang Han PARK ; Seong Wook SOHN ; Hye Ryun KANG ; Young Joo CHO
Allergy, Asthma & Respiratory Disease 2013;1(4):295-302
As the use of chemotherapeutic agents increased rapidly in recent years, more patients are under the potential risk of chemotherapy related adverse reactions. Multiple regular exposures to the same drug by chemotherapy protocol may increase the risk of sensitization to a chemotherapeutic agent, which can result in hypersensitivity reactions. Once severe hypersensitivity reactions occur, causative drugs should be avoided. However, a substitute with equal efficacy is not always available. When there is no effective alternative, desensitization is a safe tool for maintenance of chemotherapeutic agents causing hypersensitivity reaction. In this review, we introduce the latest knowledge about desensitization protocol for chemotherapeutic agents which are frequently used recently.
Antineoplastic Agents
;
Desensitization, Immunologic
;
Drug Hypersensitivity
;
Drug Therapy*
;
Humans
;
Hypersensitivity*
10.Clinical Efficacy of Subcutaneous Allergen Immunotherapy in Patients with Atopic Dermatitis.
Dong Ho NAHM ; Myoung Eun KIM ; Byul KWON ; Su Mi CHO ; Areum AHN
Yonsei Medical Journal 2016;57(6):1420-1426
PURPOSE: The clinical usefulness of subcutaneous allergen immunotherapy (SCIT) in the treatment of atopic dermatitis (AD) is still controversial. We analyzed the clinical efficacy of SCIT in patients with AD and the clinical characteristics of patients showing a favorable clinical response to the treatment. MATERIALS AND METHODS: Two hundred and fifty one patients with AD sensitized to house dust mite (HDM) were treated by SCIT using HDM extract. The clinical severity of AD was measured using the standardized clinical severity scoring system for AD (SCORAD) at baseline and 12 months. A favorable clinical response to SCIT was defined as a decrease in SCORAD value at 12 months greater than 50% compared to baseline value. Severe AD was defined as a baseline SCORAD value above 50. RESULTS: A favorable clinical response to SCIT was observed in 73.6% of patients. The proportion of patients showing a favorable clinical response to SCIT was significantly higher in patients with severe AD (90.6%) than patients with mild to moderated AD (63.7%) (p<0.001). Patients with severe AD showing a favorable clinical response had a significantly shorter duration of AD (12.3±8.5 years; mean±SD) than patients with severe AD showing no significant clinical response (20.6±10.9 years) (p<0.05) at baseline. CONCLUSION: SCIT could be a clinically useful therapeutic option for patients with severe AD sensitized to HDM. Early initiation of SCIT might provide a favorable clinical outcome in patients with severe AD sensitized to HDM.
Allergens
;
Dermatitis, Atopic*
;
Desensitization, Immunologic*
;
Humans
;
Pyroglyphidae
;
Treatment Outcome*
Result Analysis
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