No abstract available.
Dermatitis, Perioral ; Ivermectin

Childhood granulomatous perioral dermatitis is a distinctive granulomatous process of unknown cause with a benign and self-limited course and no associated systemic manifestations. We herein report a case of a 12-year-old Korean girl with multiple, discrete, monomorphic, flesh-colon, papular eruptions on the perioral, periocular, and perinasal areas of 7-month duration. Histopathologic examination revealed upper dermal and perifollicular granulomatous infiltrate.
Child ; Dermatitis, Perioral* ; Female ; Humans

Childhood granulomatous periorificial dermatitis is a distinctive granulomatous form of perioral dermatitis, characterized by a monomorphous, small papular eruption around the mouth, nose, and eyes. It occurs primarily in prepubertal children. We present a case of a 12-year-old boy with multiple, asymptomatic, erythematous papules on the perioral, perinasal and periorbital areas for 5 months. Histopathological examination revealed upper dermal and perifollicular granulomatous infiltrate. After using oral dapsone 25 mg daily for 7 weeks, the skin lesions were considerably improved. But, 3 months after discontinuence of dapsone, exacerbation of the skin lesions occurred.
Child ; Dapsone ; Dermatitis ; Dermatitis, Perioral ; Eye ; Humans ; Mouth ; Nose ; Skin

A 29-year-old man presented with well-demarcated brown-to-erythematous patches with scales on the perioral and periocular areas. We could not find any other systemic signs and symptoms, except for the cutaneous findings and no abnormal results were found on laboratory tests. Histologic examination showed upper dermal granulomatous infiltrate and led us consider the diagnosis of granulomatous periorificial dermatitis. After daily taking oral minocycline 200 mg with application of topical tacrolimus ointment for 8 weeks, combined with the application of topical tacrolimus ointment, the lesion showed a marked improvement without scarring.
Adult ; Cicatrix ; Dermatitis ; Dermatitis, Perioral ; Humans ; Minocycline ; Tacrolimus ; Weights and Measures

Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Dermatitis* ; Dermatitis, Perioral ; Humans ; Metronidazole ; Mouth ; Nose ; Tacrolimus

Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Dermatitis* ; Dermatitis, Perioral ; Humans ; Metronidazole ; Mouth ; Nose ; Tacrolimus

Childhood granulomatous periorificial dermatitis (CGPD), also known as facial Afro-Caribbean childhood eruption (FACE), is a distinctive granulomatous form of perioral dermatitis. It is a condition of unknown etiology, characterized by monomorphous, small, papular eruptions around the mouth, nose and eyes that histopathologically show a granulomatous pattern. It affects prepubescent children of both sexes and typically persists for several months but resolved without scarring. We report a 9 year-old girl with multiple, discrete, monomorphic, papular eruptions of 2-months duration on the perioral and periocular areas. Histopathological examination demonstrated upper dermal and perifollicular granulomatous infiltrate.
Child ; Cicatrix ; Dermatitis ; Dermatitis, Perioral ; Eye ; Humans ; Mouth ; Nose

BACKGROUND: Perioral dermatitis (POD) is a common inflammatory skin disease without standard therapy. OBJECTIVE: We sought to evaluate the clinical value of a soothing fluid for the treatment of POD. METHODS: We included 51 patients with POD in this 8-week clinical trial. The Toleriane Fluide Efficacy in Perioral Dermatitis (TOLPOD) study had an open-label design and involved twice-daily application of Toleriane Fluide, a soothing cosmetic fluid. Clinical assessment of POD was performed with a predefined questionnaire including the POD severity index (PODSI). Control visits were made after 4 and 8 weeks of treatment. RESULTS: The results were compared with those of a historical control group treated with a vehicle cream. Patients treated with the soothing fluid showed a continuous and significant improvement of the PODSI over time. The improvement of PODSI observed with the soothing fluid was better, but not significantly better, than that observed in the historical controls. In addition, the subjective complaints of patients such as disease burden, itching, distension of the skin, and appearance improved during treatment. CONCLUSION: A soothing fluid could be a clinically useful treatment option for POD.
Dermatitis, Perioral* ; Humans ; Pruritus ; Skin ; Skin Diseases ; Surveys and Questionnaires

A 51-year-old female developed a distinctive perioral rash, conisting of discrete or confluent erythematous papules for one and a half years. Histopathologic examiriation revealed upper dermal granulomas admixed with lymphoytes. Pieces of hair shaft were staincd peri-dish by AFB in the center of granuloma, which might play a role in the formation of the granuloma She also had used corticosteroid ointment intermittently duririg this time. There were no associated systemic abnormalities. The lesions resolved after two month treatment with oral corticosteroid and tetrac cline.
Dermatitis, Perioral* ; Exanthema ; Female ; Granuloma ; Hair ; Humans ; Middle Aged

BACKGROUND: Periocular dermatitis (PD) is a common condition and can be classified as either allergic or non-allergic. Because the periocular region is one of the most sensitive areas of the skin, contact with any environmental or therapeutic allergen may give rise to dermatitis. OBJECTIVE: The aim of this study was to investigate the clinical usefulness of patch testing to determine sensitivity to contact allergens in PD patients. METHODS: Patch testing was conducted in 29 PD patients using the T.R.U.E. test(R) at Pusan National University Hospital. We examined the results of patch testing, the probable cause of PD, and the history of use of ophthalmic medication. RESULTS: Contact hypersensitivity was detected using the T.R.U.E. test(R) in 62.1% (18/29) of the patients, and contact hypersensitivity to specific ophthalmic medications was observed in 33.3% (3/9) of the patients with a history of using ophthalmic medication. CONCLUSION: We suggest that patch testing can be utilized to elucidate the relevant contact allergen in patients with PD. Patch testing with specific ophthalmic medications is valuable to determine allergic reactions in patients who have used ophthalmic medications.
Allergens* ; Busan ; Dermatitis ; Dermatitis, Contact ; Dermatitis, Perioral* ; Humans ; Hypersensitivity ; Patch Tests* ; Skin