Plant dermatitis can be classified as primary irritant dermatitis, allergic contact dermatitis, phytophotodermatitis and pseudophytophotodermatitis. Among these, allergic contact dermatitis is seen most freguently. It is generally known that dermatitis causing plants have various characteristics depending on the habitat af different plants. Until now we have had great difficulty in finding the causative factors in plant dermatitis in Korea. This is due to the fact that we do not have anr comprehensive reports regarding domestic or imported timbers concerned in contact dermatiti. The purpose of this thesis is to gather the basic materials necessary to discover the cauae of plant contact dermatitis. All kinds of trees, flowers, and grasses in Korea and imported timbers concerned with contact dermatitis were considered in this study. We strove to ascertain whether the species in our country are the same as found in foreign countries or other different speceies are in our country under the sarne genus found in foreign countries. The basis for our study is several Korean plant books as well as interviews with several native botanists. Vie also discussed major families af plants causing or possible causing plant dermatitis in Korea.
Dermatitis ; Dermatitis, Allergic Contact ; Dermatitis, Contact* ; Dermatitis, Irritant ; Ecosystem ; Flowers ; Humans ; Korea ; Plants ; Poaceae ; Trees

The clematis apiifolia A.P. DC. is a plant which belongs to Clematis Linne, Ranunculaceae. It contains anemonol, clematiscampher, clematin, labenzyme, saponin, of which anemonol is a probable irritant reacting component. We report two cases of irritant dermatitis due to Clematis apiifolia A.P.DC. plant. These patients developed painful, inflamed erythematous patches with flaccid bullae and erosions on the application sites of the crushed plant for self-treatment of arthralgia.
Arthralgia ; Clematis* ; Dermatitis, Irritant* ; Humans ; Plants ; Ranunculaceae ; Saponins

Ranunculus tachiorei is a member of the buttercup family (Ranunculaceae) which contains unsaturated lactone and protoanemonine. Protoanemonine is formed by the breakdown of the glycoside Ranunculin after injury to the plant and causes severe vesiculation and linear streaks after contact with field buttercups(Ranunculus spp.) The amount of protoanemonine in buttercups varies widely with the species of plant and its stage of growth, the highest content being at the time of flowering. We report a case of primary irritant dermatitis due to contact with Ranunculus Tachiorei which was applied for the folk treatment of Bell palsy.
Bell Palsy ; Dermatitis, Irritant* ; Flowers ; Humans ; Plants ; Ranunculus*

1. Napotol solution was topically applied on a trial basis for the treatment of superficial fungal infections and 56% of patients had an excellent benefit and 14% of patients had an irritant dermatitis during the treatment. 2. The main compoeition of Napotol solution is drived from ethsnolie extraction of a natural plant and it's pharmacological action to fungal infection is not known,, yet it's antifungal action is potent as compared to other antifungal topical medicines, Napotol solution also including salicylic acid and benzoic acid, which are well known as possessing a potent antifungal property, may be accelerating it's function for the treatment of superficial fungal infection.
Arthrodermataceae* ; Benzoic Acid ; Dermatitis, Irritant ; Humans ; Plants ; Salicylic Acid

Irritant dermatitis is the most frequent type of plant-related dermatitis. Plant families most commonly associated with irritation are Ranunculaceae, Euphorbiaceae, Cruciferae, Brassicaceae, Urticaceae, and Solanaceae. We report a case of irritant contact dermatitis caused by Ranunculus japonicus for the treatment of arthralgia in a 78 year old female.
Aged ; Arthralgia ; Brassicaceae ; Dermatitis ; Dermatitis, Contact ; Dermatitis, Irritant* ; Euphorbiaceae ; Female ; Humans ; Plants ; Ranunculaceae ; Ranunculus* ; Solanaceae ; Urticaceae

The buttercup is an inportant irritant plant which contairs an unsaturated lactone, protoanemonin, formed by the breakdown of a glucoside in injured plants. We report the three cases of irritant contact dermatitis due to buttercup(Ranunculus sceleratus). These patient developed erythematous and edematous patches with tense vesicles or bullae on t,he application site of pounded buttercup for the treatment of diabetes mellitus, arthralgia, and neuralgia, respectively.
Arthralgia ; Dermatitis, Contact ; Dermatitis, Irritant* ; Diabetes Mellitus ; Humans ; Neuralgia ; Plants ; Transcutaneous Electric Nerve Stimulation

Granuloma gluteale infantum has been applied to a condition arising as a complication of primary irritant dermatitis. Plastic pants, and the use of topical corticosteroids to treat diaper dermatitis are believed to be important precipitating factors. Candida albicans has been considered as an etiologic agent. The characteristic lesions are violaceous, oval nodules, occuring on the convexities of the diaper area in 2- to 9-month-old infants with a history of diaper dermatitis. We report a case of granuloma gluteale infantum that developed in a 3 month-old infant who had multiple violaceous nodules over the diaper area of the genitocrural region.
Adrenal Cortex Hormones ; Candida albicans ; Dermatitis ; Dermatitis, Irritant ; Granuloma* ; Humans ; Infant ; Plastics ; Precipitating Factors

Dermatitis, Contact ; diagnosis ; etiology ; therapy ; Dermatitis, Irritant ; diagnosis ; etiology ; therapy ; Humans

Paraquat(Gramoxone) is the most commonly used herbicide in Korea. But serious paraquat poisoning in human beings has occurred following ingestion or exposure to the skin. Exposure to paraquat through the skin has resulted in local irritation or inflammation of varyiig degree, sometimes severe. We report three cases of primary irritant dermatitis due to paraquat. Two patients developed generalized vesicobullae and necrotirulcer in the scrotum, respectively. The other patient developed painful whitish patch and erosion in ttie tongue after accidental exposure.
Dermatitis, Irritant* ; Eating ; Humans ; Inflammation ; Korea ; Paraquat ; Poisoning ; Scrotum ; Skin ; Tongue

BACKGROUND: In the skin, the major stimulus for cutaneous pigmentation is ultraviolet radiation. The most important physiologic role of melanin is protection against harmful UV radiation to skin. It is known there are some differences in melanization between a single and multiple exposures of UVB, in vivo. Little if known about the functions of the melanocyte alone in cutaneous pigmentation after ultraviolet exposure, because of the complexity of interactions in the whole epidermis. OBJECTIVE: To investigate the effects of multiple exposures at various dosages of UVB, and to compare the effect of UVB in multiple divided exposures with a single exposure at the same total dosage of UVB on proliferation and melanization in cultured human melanocyte. METHODS: Melanocytes were cultured by modified TIC medium. The melanoctes were exposed daily for three consecutive days to UVB at 2, 4, 8 and 16 mJ/cm2and a single exposure at 24 mJ/cm2. The morphologic changes were examined by phase contrast microscopy. The melanocytes were counted by hemocytometer and melanin contents were assayed by spectrophotometer. RESULTS: 1. The effects of multiple UVB exposures: 1) The morphologic changes were as follows: With three time exposures at a dosage of 8 mJ/cm2, themelanocytes enlarged in size, and elongated their dendrites slightly; with three time exposures at a dosage of 16 mJ/cm2, enlargement in sized and elongation of dendrited were more significant. 2) With three time exposures at dosages of 2 nd 4 mJ/cm2, the proliferation of melanocytes was stiumlated significantly(p<0.05). However, with three time exposures at dosages of 8 and 16 mJ/cm2the proliferation was inhibited(p<0.05). 3) With three time exposures at dosages of 2 and 4 mJ/cm2, the melanin contents were decreased. However, with three tiem exposures at a dosage of 16 mJ/cm2, the melanin contents were highly increased(p<0.01). 2. The comparison between multiple divided exposures and a single exposure at the same toal dosage of UVB: 1) There were no morphologic differences of dendrities between with three time exposures at a dosage of 8 mJ/cm2 and with a single exposure at a dosage of 24 mJ/cm2. However enlarged melanocytes were more numerous with a single exposure. 2) The proliferation of melanocytes was more inhibited with a single exposure than with multiple divided exposures(p<0.05). 3) The melanin contents were more increased with a single exposure than with multiple divided exposures(p<0.05). CONCLUSION: With multiple exposures at lower dosages of UVB, the proliferation of melanocytes was stimulated, and melanization was decreased. However, with multiple exposures at higher dosages of UVB, the proliferation was inhibited, and melanization was increased. At the same total dosage of UVB, the proliferation was more inhibited, and the melanization was more increased with a single exposure than with multiple divided exposures.
Dendrites ; Dermatitis, Irritant ; Epidermis ; Humans* ; Melanins ; Melanocytes* ; Microscopy, Phase-Contrast ; Pigmentation ; Skin ; Tics