1.A case series of dermatological emergencies – Erythroderma
The Medical Journal of Malaysia 2017;72(2):141-143
Erythroderma can be life-threatening, primarily because of
its metabolic burden and complications. It is mandatory to
establish its etiopathology in order to facilitate precise and
definitive management. This disorder may be the
morphologic presentation of a variety of cutaneous and
systemic diseases. Detailed history and thorough work-up is
therefore essential. Management of erythroderma involves
multi-disciplines with progress monitoring especially on
signs and symptoms suggestive of acute skin failure
induced complications. Early diagnosis and referral of
erythroderma to centres with dermatological services is
crucial and will directly affect the outcome of the patients.
Dermatitis, Exfoliative
2.Epidemiology of exfoliative dermatitis at the University of Santo Tomas Hospital (Department of Dermatology) from 2008-2012: A five-year review
Niñ ; a A. Gabaton ; Daisy K. Ismael
Journal of the Philippine Dermatological Society 2020;29(1):56-62
INTRODUCTION: Exfoliative dermatitis is a potentially life- threatening inflammatory reaction that poses a significant risk for morbidity and mortality. Several underlying etiologies of this dermatologic condition include pre-existing dermatoses, drugs and malignancy. Although it is a common disease entity, local studies on exfoliative dermatitis published in literature are very limited.
OBJECTIVE: The primary objective of this study is to determine the epidemiological profile of patients with exfoliative dermatitis diagnosed at University of Santo Tomas Hospital Dermatology department from January 2008 to December 2012.
METHODS: Inpatient and outpatient clinical records of patients diagnosed and treated as exfoliative dermatitis were retrieved. The prevalence, clinical presentation, history of previous dermatoses or use of any drugs/topical medications, family history and accompanying systemic symptoms were reviewed and analyzed.
RESULTS: A total of 67 patients were included in this retrospective study. The prevalence among patients with exfoliative dermatitis in this study was computed at 1 per 1000 dermatologic patients. The highest number of cases belonged to the group aged seventy-one to seventy-nine (25.4%) with a mean age of 56.62 years. There was a male predilection (65.7%). Clinical presentation of patients included pruritus, generalized scaling and erythema, accompanied by bipedal edema (41.8%), chills (22.4%), fever (T ≥ 38 °C), lymphadenopathies (6%) and joint pains (4.5%). Several etiologic factors of exfoliative dermatitis recorded were: pre-existing dermatosis (67.2%), idiopathic or undetermined causes (19.4%), drug-induced (10.4%) and malignancy (3%).
CONCLUSION: Exfoliative dermatitis is a condition more commonly found in the older age group. Pre-existing dermatoses, drugs and malignancy are etiologic factors. The most common pre-existing dermatosis causing exfoliative dermatitis in this study is psoriasis while the most implicated drug is allopurinol.
Dermatitis, Exfoliative
3.A Case of Exfoliative Dermatitis Induced by Phototherapy Secondary to Pustular Psoriasis
Su Jung PARK ; Guk Jin JEONG ; Jun Ki HONG ; Seong Jun SEO
Korean Journal of Dermatology 2019;57(9):556-557
No abstract available.
Dermatitis, Exfoliative
;
Phototherapy
;
Psoriasis
4.A Case of Erythrodermic Dermatomyositis Associated with Gastric Cancer.
Sung Woo KIM ; Yoo Seok KANG ; Sang Hoon PARK ; Un Ha LEE ; Hyun Su PARK ; Sang Jai JANG
Annals of Dermatology 2009;21(4):435-439
Erythroderma is an unusual cutaneous finding associated with dermatomyositis. There are only five cases of erythrodermic dermatomyositis reported in the English literature. We treated a case of erythrodermic dermatomyositis associated with a Bormann type 1 gastric cancer. The patient had a generalized, erythematous scaly eruption consistent with erythroderma and Gottron's papules as well as a heliotrope rash; these are the hallmark skin manifestations of dermatomyositis.
Dermatitis, Exfoliative
;
Dermatomyositis
;
Humans
;
Skin Manifestations
;
Stomach Neoplasms
5.A Case of Papuloerythroderma of Ofuji.
Jin Seok YANG ; Shin Taek OH ; Chul Jong PARK
Korean Journal of Dermatology 2002;40(2):158-161
Papuloerythroderma of Ofuji is a rare, distinctive clinical entity characterized by a widespread pruritic eruption of coalescence of flat-topped erythematous papules producing an erythroderma with sparing of the skin folds (the 'deck-chair' sign). Other common features of papuloerythroderma are blood eosinophilia, lymphopenia, a raised serum IgE and a nonspecific or eczematous-like histopathologic feature. Its etiology has been reported as variable, and the condition is thus considered as a pattern of cutaneous expression induced by a range of pathological process for systemic disease. We experienced a 71-year-old male patient with a 4-month history of a generalized pruritic eruption which clinical features were compatible with papuloerythroderma of Ofuji. Treatment with systemic steroid resulted in marked improvement.
Aged
;
Dermatitis, Exfoliative
;
Eosinophilia
;
Humans
;
Immunoglobulin E
;
Lymphopenia
;
Male
;
Skin
6.Exfoliative Dermatitis Caused by Herbal Extract of Saururus chinesis baill.
Korean Journal of Dermatology 2006;44(6):776-778
Exfoliative dermatitis is caused by various etiologic factors including preceding dermatosis, drug-use, malignancy-related reasons and idiopathies. We present an exfoliative dermatitis caused by topical application of the herbal extract, Saururus chinesis baill. Saururus chinesis bail has been used traditionally as a folk remedy for various kinds of dermatoses in Korea. Therefore, the public should be warned of indiscreetly-used, natural, but not purified, herbal products.
Dermatitis, Exfoliative*
;
Korea
;
Medicine, Traditional
;
Saururaceae*
;
Skin Diseases
7.Exfoliative Dermatitis Induced by Minocycline.
Korean Journal of Dermatology 2001;39(1):99-101
Exfoliative dermatitis is characterized by a universal or very extensive obstinate scaling and itching erythroderma. Although the clinical picture is similar in most patients, there are many etiologic factors in exfoliative dermatitis. We report a case of exfoliative dermatitis developed in a 22-year-old male patient who had been taking oral minocycline (100 mg twice daily) for 5 weeks for acne.
Acne Vulgaris
;
Dermatitis, Exfoliative*
;
Humans
;
Male
;
Minocycline*
;
Pruritus
;
Young Adult
8.Papuloerythroderma of Ofuji.
Min Sung KIM ; Hoon CHOI ; Chan Ho NA ; Kyu Chul CHOI ; Bong Seok SHIN
Journal of the Korean Geriatrics Society 2012;16(4):217-220
Papuloerythroderma of Ofuji is a rare type of erythroderma of the elderly and consists of flat-topped erythematous papules that coalesce, forming diffuse sheets that characteristically spare skin folds (so called 'deck-chair' sign). The etiopathogenesis of the disease remains unknown, but a number of cases have demonstrated the connection of this disorder with malignancy, mainly cutaneous T cell lymphoma. We report a case of papuloerythroderma of Ofuji unassociated with underlying malignancy, with the biopsy specimen showing nonspecific eczematous findings. There are cases of papuloerythroderma of Ofuji associated with malignancy, and one needs to be mindful of such in examinations.
Aged
;
Biopsy
;
Dermatitis, Exfoliative
;
Humans
;
Lymphoma, T-Cell, Cutaneous
;
Skin
9.Clinical Study of Cyclosporin A for Psoriasis in China.
Liao WANQUNG ; Li ZHIGANG ; Hong WEI
Annals of Dermatology 1995;7(4):313-317
BACKGROUND: The efficacy of Cyclosporin A(CyA) in the treatment of psoriasis is well recongized, the dosage less than 5mg/kg per day(mg/kg/d) is recommended. OBJECTIVE: The purpose of this study is to evaluate the indication, dose, course and side-effects of CyA therapy for psoriasis, especially in China. METHODS: Forty patients with psoriasis were treated with doses of CyA 5mg/kg/d, compared with 20 patients treated with Tigason lmg/kg/d by Global PAST. RESULTS: 1. Of 40 patients 33 patients (82.5%)were cured clinically in 4-5weeks and all the patients(100%) had responses to the therapy. 2. The efficacy and the Global PASI reduction of CyA therapy were significantly better than that of Tigason therapy. 3. During the CyA therapy, no severe side-effects and obvious laboratory changes were found. CONCLUSION: CyA(5mg/kg/d) was satisfactory for psoriasis, especially for psoriasis pustulosa, arthropathica and erythroderma. CyA was found to be superior to Tigason. The therapy course and side-effects seemed to be related to the dosage.
China*
;
Clinical Study*
;
Cyclosporine*
;
Dermatitis, Exfoliative
;
Etretinate
;
Humans
;
Psoriasis*
10.Eccrine Syringofibroadenoma in a Patient with Long-Standing Exfoliative Dermatitis.
Eun Jung KO ; Kui Young PARK ; Hyun Jung KWON ; Joo Hyun SHIM ; Seong Jun SEO
Annals of Dermatology 2016;28(6):765-768
Eccrine syringofibroadenoma (ESFA) is a rare benign cutaneous adnexal lesion characterized by a hyperplastic epithelium and eccrine ductal differentiation. In the present case, a 73-year-old Korean male presented with symmetrical numerous widespread, pinkish nodules with a cobblestone appearance over both legs for 2 years. He had a history of generalized erythematous scaly patches over his entire body for 20 years. On histopathologic findings, diagnosis of ESFA was confirmed. Our unusual and interesting case emphasizes the first report described one case in which multiple cobblestone like ESFAs arising from long-standing exfoliative dermatitis.
Aged
;
Dermatitis, Exfoliative*
;
Diagnosis
;
Epithelium
;
Humans
;
Leg
;
Male