The Wolff-Parkinson-White (W-P-W) syndrome and variants are called the pre-excitation sydrome. The prevalence has been estimated 0.15 pereent. Advances in electrophysiological mapping and increasing sophistication of surgical techniques have been resulted in an increasing role for definitive surgical treatment. The anesthetic management of patients with this syndrome is aimed at avoiding tachyarrhythmias. Anesthesia for surgical ablation of accessory conducting pathways was successfully performed under general balanced technique with fentantyl, vecuronium, isoflurane which were avoid of sympathetic stimulation.
Accessory Atrioventricular Bundle ; Anesthesia ; Humans ; Isoflurane ; Prevalence ; Tachycardia ; Vecuronium Bromide ; Wolff-Parkinson-White Syndrome

About 40% of patients with diabetes mellitus develops to diabetic nephropathy, and these patients show increment of glomerular filtration rate and renal volume at early phase. 99mTc-DMSA SPECT (single photon emission computed tomography) can measure a functional renal volume because 99mTc- DMSA it is taken up by the viable proximal tubular cells located in the renal cortex. To evaluate the renal volume in early diabetic nephropathy, we compared functional renal volume between diabetic patients and control, renal transplantation donor. 99mTc-DMSA was injected intravenously and SPECT was done after 2 hours in 15 diabetic patients, 18 renal transplantation donors, and 2 patients with end stage renal disease due to chronic glomerulonephritis. In diabetic patients with creatinine clearance more than 30ml/min and proteinuria, right and left renal volume were 247+/-22ml/BSA(m2), 256+/-37ml/BSA (m2), which were greater than those of diabetic patients with normal renal function and without proteinuria, or renal transplantation donors(P<0.05). In conclusion, we measured the functional renal volume by 99mTc-DMSA SPECT. Renal volume of diabetic patients with proteinuria were larger than the volume of control group or diabetic patients with normal renal function and without proteinuria. 99mTc-DMSA SPECT was thought to be useful test a for the measurement of functioning renal volume.
Creatinine ; Diabetes Mellitus* ; Diabetic Nephropathies ; Glomerular Filtration Rate ; Glomerulonephritis ; Humans ; Kidney Failure, Chronic ; Kidney Transplantation ; Proteinuria ; Succimer ; Technetium Tc 99m Dimercaptosuccinic Acid* ; Tissue Donors ; Tomography, Emission-Computed, Single-Photon*

No abstract available.
Brain* ; Tomography, Emission-Computed, Single-Photon*

The authors report series of 360 cases of transthoracic fine-needle aspiration cytology (TFNA) from Oct. 1982, through Aug. 1986 at the Seoul National University Hospital. A diagnosis of neoplastic lesion was established in 50.3% of the cases. A non-neop- lastic diagnosis was made in 38.5%, nondiagnostic one in 6.5% and inadequate one in 4.7% of the total. Statistical findings on cytological diagnoses were as follows. Specificity was 100%: sensitivity, 92%; predictive value for positive, 1.0: predictive value for negative, 0.9; concordance rate, 84.2%: diagnostic accuracy in non-neoplastic lesion, 65.4%, and typing accuracy in malignant tumor, 0.77.
Biopsy, Fine-Needle ; Diagnosis ; Glomerulonephritis, IGA* ; Immunoglobulin A* ; Sensitivity and Specificity ; Seoul

Natural products in Chonnam, Korea were screened via anti-angiogenesis experiments, and 1 candidate product was identified, Corni fructus, which exerted dose-dependent inhibitory effects against angiogenesis, adipogenesis, and cell adhesion. C. fructus extract (CFE) exhibits an angiogenesis inhibitory effect superior to that of the EGCG from green tea leaves. The expression level of angiogenesis and adipogenesis-related signal molecules in the western blotting was reduced by increasing the amount of added CFE. Moreover, a diet supplemented with CFE was deemed more effective in inducing weight loss in LB mice than a representative synthetic diet drug, orlistat, which incidently caused the side effect of denuding the mice of their hair. These results indicate that C. fructus may prove to be a useful anti-adipogenic compound, and these in vitro results may be reflected later under in vivo conditions.
Adipogenesis ; Animal Experimentation ; Animals ; Biological Agents ; Blotting, Western ; Cell Adhesion ; Cornus ; Diet ; Food, Formulated ; Hair ; Korea ; Lactones ; Mice ; Tea ; Weight Loss

OBJECTIVE: This study is aimed to evaluate a sit-to-stand (STS) pattern in the children with spastic diplegic cerebral palsy in comparison with the normal children. METHOD: Fifteen young children with spastic diplegic cerebral palsy and 21 normally developed children were recruited as subjects. A motion analysis system using a Motion analyzer (Vicon 370 M.A. with 6 infrared cameras) was used to examine the STS task. The changes in joint angle, moment, and power of each joints in lower limbs, total duration of STS transfer and each transitional points were assessed. RESULTS: Total duration of STS in patients was 2.44 sec, which was significantly prolonged in comparing with 1.10 sec in normal control. The major prolongation of STS occurred in the phase of vertical movement of center of mass (CoM). Cerebral palsied children showed more anterior pelvic tilting and hip flexion throughout STS transfer than normal control. Asymmetries in initial angle of ankle and maximal momentum of knee extension were shown in spastic diplegic children with cerebral palsy, but not in normal control. Less extension momentum and power of knee joint and more plantar flexion momentaum of ankle joint were observed in cerebral palsy in comparing with those of normal children. CONCLUSION: This study showed that STS pattern in spastic diplegic cerebral palsy was quite different from that of normal children. The characteristics of STS pattern in these children was slowness of speed; mainly from slowness of vertical displacement of CoM, and more anterior pelvic tilt, hip flexion and earlier abrupt change of knee extension. As well, the major moments required for this task in these patients occurred at hip and ankle joints instead of knee joint.
Ankle ; Ankle Joint ; Cerebral Palsy* ; Child* ; Hip ; Humans ; Joints ; Knee ; Knee Joint ; Lower Extremity ; Muscle Spasticity*

No abstract available.
Bismuth* ; Gentamicins* ; Mercuric Chloride*

The arterial variations of the upper limb are frequently encountered in the human body. However, the appearance of multiple variations in one limb is uncommon. The present arterial variations were found in the right upper limb of 86 years-old female cadaver during a routine dissection. The variations of the arterial patterns are as follows: 1. Two thyrocervical trunks from subclavian artery and the internal thoracic artery is rising from lateral branch of thyrocervical trunks. 2. Thoracoacromial artery was divided two branches and the lateral thoracic artery arises from the small of two branches. 3. The distance of bifurcation of the brachial artery is 14.9 mm from the inferior border of teres major muscle. Medial branch of the brachial artery passes along the median nerve and becomes radial artery. Lateral branch of the brachial artery passes along the median nerve and becomes ulnar artery. 4. Bifurcation of radial artery is occurred at the distance of 46.9 mm from styloid process of radius. Deep palmar branch of radial artery is bifurcated on dorsum of hand. Branches for supplying first and second fingers arise from superficial palmar arch. The arterial variations of the upper limb could be caused a several bleeding in intravenous injection or surgeries and a wrong diagnosis. The knowledge of the arterial variation of the upper limb should be decreased to raise clinical problems.
Arteries ; Brachial Artery ; Cadaver ; Extremities ; Female ; Fingers ; Hand ; Hemorrhage ; Human Body ; Humans ; Injections, Intravenous ; Mammary Arteries ; Median Nerve ; Muscles ; Radial Artery ; Radius ; Subclavian Artery ; Thoracic Arteries ; Ulnar Artery ; Upper Extremity

OBJECTIVE: Alexithymic characteristics may represent cognitive and affective mediators between stressors and stress responses among those with depressive disorders. This study evaluated how alexithymic characteristics, as measured by the Korean version of the Toronto Alexithymia Scale-20 (TAS-20K), could be related to stress response patterns, as measured by the Stress Response Inventory (SRI), within a sample composed of individuals diagnosed with depressive disorders. METHODS: Participants comprised a cross section of patients diagnosed with depressive disorders (n=98). Data on demographic and psychosocial factors (i.e., sex, age, and level of education), clinical profiles {i.e., primary and comorbid psychiatric conditions meeting the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) criteria at the time of the evaluation}, duration of illness, medications, and Clinical Global Impression (CGI) scores, and the results of psychological assessments (TAS-20K, SRI) were analyzed. RESULTS: Patients having depressive disorders with alexithymia obtained significantly higher scores in terms of all seven subscales of the SRI, as compared to those without alexithymia, a logistic regression model was used to assess possible predictors for the presence of alexithymia in patients with depressive disorders, including the seven subscales of the SRI, gender, age, and duration of illness. We found that aggressive and somatizing responses to stress were significantly associated with the presence of alexithymia among patients with depression. CONCLUSION: These findings suggest that patients having depression with alexithymia were more susceptible to stress than those without alexithymia. Clinicians might improve their treatment of depression by identifying the clinical predictors for alexithymia and by helping those individuals demonstrating such symptoms in coping with emotionally stressful situations.
Affective Symptoms ; Depression ; Depressive Disorder ; Diagnostic and Statistical Manual of Mental Disorders ; Humans ; Korea ; Logistic Models

Chronic hypoventilation due to injury to the brain stem respiratory center or high cervical cord (above the C3 level) can result in dependence to prolonged mechanical ventilation with tracheostomy, frequent nosocomial pneumonia, and prolonged hospitalization. Diaphragm pacing through electrical stimulation of the phrenic nerve is an established treatment for central hypoventilation syndrome. We performed chronic phrenic nerve stimulation for diaphragm pacing with the spinal cord stimulator for pain control in a quadriplegic patient with central apnea due to complete spinal cord injury at the level of C2 from cervical epidural hematoma. After diaphragmatic pacing, the patient who was completely dependent on the mechanical ventilator could ambulate up to three hours every day without aid of mechanical ventilation during the 12 months of follow-up. Diaphragm pacing through unilateral phrenic nerve stimulation with spinal cord stimulator was feasible in an apneic patient with complete quadriplegia who was completely dependent on mechanical ventilation. Diaphragm pacing with the spinal cord stimulator is feasible and effective for the treatment of the central hypoventilation syndrome.
Apnea ; Brain Stem ; Diaphragm* ; Electric Stimulation ; Follow-Up Studies ; Hematoma ; Hospitalization ; Humans ; Hypoventilation ; Phrenic Nerve* ; Pneumonia ; Quadriplegia ; Respiration, Artificial ; Respiratory Center ; Sleep Apnea, Central ; Spinal Cord ; Spinal Cord Injuries ; Tracheostomy ; Ventilators, Mechanical ; Wounds and Injuries