OBJECTIVEThe aim of the present study is to investigate the prognosis and influencing factors of crown-fractured young permanent teeth with pulp exposure.

METHODSCase records of crown-fractured young permanent teeth with pulp exposure in the Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology during 1991 to 2008 with more than 2 years follow-up were collected. These patients were treated with pulpotomy at the first visit at our hospital no matter whether these teeth were treated or untreated with direct pulp capping. The age of patients, interval between trauma and treatment, root development, mobility and tenderness to percussion were recorded. The prognosis was analyzed and Logistic regression was used to analyze the influencing factors.

RESULTSTotally 118 cases satisfied the inclusion criteria, including 136 crown-fractured teeth with pulp exposure. The patients of (8.8 +/- 1.2) years old were periodically monitored for (46.1 +/- 22.0) months. The success rate of pulpotomy after pulp exposure was 85.3%. Pulp necrosis occurred in 20 teeth (25.0 +/- 19.0) months after trauma. The extent of tenderness to percussion showed significant correlation with pulp necrosis, while the age of the patients, interval between injury and treatment, and mobility of the teeth were not related to pulp necrosis.

CONCLUSIONThe success rate of pulpotomy after pulp exposure is good. Tenderness to percussion is an important signal of pulp necrosis. There are no evidence about the relationship between the patient's age, interval between injury and treatment, mobility of the pulp-exposed teeth and the pulp prognosis.

Age Factors ; Child ; Crowns ; Dental Pulp ; Dental Pulp Exposure ; Dental Pulp Necrosis ; Humans ; Incisor ; Male ; Prognosis ; Pulpotomy ; Retrospective Studies ; Root Canal Therapy ; Tooth Crown ; Tooth Fractures

OBJECTIVE: To assess the feasibility and efficacy of simvastatin-collagen composite sponge as a novel, direct pulp capping material. METHODS: A total of 120 Sprague-Dawley rats were randomly divided into three groups: the simvastatin-collagen composite sponge group (SIM group), the collagen sponge group (CS group), and the Ca(OH)2 group (CH group). An endodontic entry cavity was prepared on the occlusion of the first molar on the left maxillary of each rat. The contralateral teeth were utilized as the normal control group. The rats were experimented after 1, 3, 7, 14, and 28 days. X-ray observations were conducted and the specimens underwent hematoxylin-eosin (HE) and Masson's Thichrome staining. Dentin bridge formations and pulpal biology reactions were evaluated histopathologically. RESULTS: X-ray results: high-density images could be observed on the pulp exposure sites in the CH group on the 28th day. In the SIM group, high-density images could be observed after 14 and 28 days, whereas in the CS group, high-density images were not observable in the exposed area. HE and Masson's Thichrome staining results: different degrees of inflammation under the cavity were detected in the three groups at different time points. The inflammatory reaction of the CS group was the most serious. The degree of the inflammatory reaction varied significantly between the SIM and the CS groups on the 14th and 28th days (P<0.01). The inflammatory reaction in the SIM group was lighter than in the CH group. There was a statistical difference between the SIM and the CH groups on the 14th day (P<0.05). During the observation period, the SIM group induced the best and fastest formation of reparative dentin. As for dentin bridge formation, a significantly higher complete bridge rate was observed in the SIM group than in the CH and in the CS groups on the 14th day (P<0.05) and for the SIM and the CH groups compared with the CS group on the 28th day (P<0.05). CONCLUSIONS The simvastatin-collagen composite sponge exhibited satisfactory biocompatibility with the pulp tissue and promoted the formation of reparative dentin. The application of simvastatin-collagen composite sponge as a pulp-capping material has satisfactory potential.
Animals ; Calcium Hydroxide ; Collagen ; Dental Pulp ; Dental Pulp Capping ; Dental Pulp Exposure ; Dentin, Secondary ; Molar ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Simvastatin

Child ; Dental Pulp Exposure ; etiology ; therapy ; Dental Restoration, Permanent ; Dental Restoration, Temporary ; Humans ; Incisor ; injuries ; Pulpotomy ; methods ; Root Canal Therapy

A visible light-curing calcium hydroxide cement is presented here and the effects of its resin matrix on the Ca2+ releasing, compressive strength of set material and the pH value of water in which set materials immersed are evaluated. Experimental results show that the effects of the selected resin matrix on Ca2+ releasing, compressive strength and pH value are significant. The calcium hydroxide cement containing BEMA or EMA and HEMA as resin matrix has good properties. The pulp capping test showed that an excellent dentin bridge appeared in dogs capped teeth at 70 days. pulp, pulp capping, calcium hydroxide, visible light-curing, dental materials
Animals ; Calcium ; metabolism ; Calcium Hydroxide ; radiation effects ; therapeutic use ; Composite Resins ; chemistry ; radiation effects ; therapeutic use ; Dental Cements ; therapeutic use ; Dental Pulp Capping ; instrumentation ; Dental Pulp Exposure ; therapy ; Dogs ; Light ; Time Factors