1.Spermatocytic Seminoma With Sarcoma: An Indication for Adjuvant Chemotherapy in Localized Disease.
David WETHERELL ; Nathan LAWRENTSCHUK ; Dennis GYOMBER
Korean Journal of Urology 2013;54(12):884-887
Spermatocytic seminoma (SCS) with sarcoma is an extremely rare testicular tumor with only 11 cases previously described in the literature. We present the 12th case of SCS with sarcoma in a 29-year-old male. SCS itself is an uncommon germ cell tumor with a relatively indolent clinical course that mostly affects males around the fifth decade of life. Sarcomatous differentiation of SCS occurs in 5% to 6% of cases and correlates with a higher possibility of metastatic disease and a poor prognosis. Clinically, this tumor manifests as a slow-growing testicular mass often with an accelerated period of secondary growth. After a concise review of the literature, we conclude that SCS with sarcoma should be treated by radical inguinal orchidectomy with strong consideration given to adjuvant chemotherapy.
Adult
;
Chemotherapy, Adjuvant*
;
Humans
;
Male
;
Neoplasms, Germ Cell and Embryonal
;
Orchiectomy
;
Prognosis
;
Sarcoma*
;
Seminoma*
;
Testicular Neoplasms
;
Testis
2.Nephrectomy for a Renal Metastasis of Undiagnosed Hepatocellular Carcinoma Arising From an Orthotopic Liver Transplant Undertaken for Cryptogenic Cirrhosis.
Kevin W K ONG ; Binoy JOSEPH ; Dennis V GYOMBER ; Damien M BOLTON ; Nathan LAWRENTSCHUK
Korean Journal of Urology 2013;54(10):715-717
Urological involvement of hepatocellular carcinoma (HCC) is rare; HCC arising in an orthotopic liver transplant (OLT) is exceptionally rare. Here we report the case of a 70-year-old man who was incidentally found to have metastatic HCC in the right kidney arising from his OLT undertaken for cryptogenic cirrhosis 10 years previously. Adding to the complexity of this case was the lack of an obvious liver primary HCC at the time of the radical nephrectomy, thus making the final diagnosis all but impossible. We believe this report represents the first report of HCC metastasizing to the kidney after OLT and adds to the few reports in the literature of HCC arising in transplanted livers.
Aged
;
Carcinoma, Hepatocellular
;
Fibrosis
;
Humans
;
Kidney
;
Kidney Neoplasms
;
Liver
;
Liver Neoplasms
;
Liver Transplantation
;
Neoplasm Metastasis
;
Nephrectomy
;
Transplants