1.ТОЛГОЙ ХҮЗҮҮНИЙ БАЙРЛАЛТАЙ ХОРТОЙ ХАВДРЫН МЭС ЗАСАЛ ЭМЧИЛГЭЭНИЙ ДАРААХ БИЧИЛ СУДАС ЗАЛГАН ЧӨЛӨӨТ ДАЛБАН ШИЛЖҮҮЛЭН СУУЛГАСАН ЭРТ ҮЕИЙН ТУРШЛАГА
Denis S ; Gan-Erdene B ; Battsengel B ; Enkhtuul M ; Ariunbaatar G ; Purevdorj G
Innovation 2017;3(3):26-27
BACKGROUND. Head and neck cancers are related group of cancers that involve the oral cavity, pharynx (oropharynx, nasopharynx, hypopharynx), and larynx. Early-stage tumors of the upper aerodigestive tract can be cured; for late-stage disease, prognosis is poor. Nowadays microvascular free tissue transfer surgery performed at high level. Worldwide, this particular kind of operation in head and neck surgical field has become “golden standard” of treatment. Seemingly, plastic and reconstructive surgeons of developed countries widely perform forearm free flap, anteriolateral thigh free flap, fibula free flap, rectus abdominal free flap, latissimusdorsi free flap. We purpose to report our first 121 cases of Microvascular Free Tissue Transfer which had been performed at the head and neck surgical department, NCC of Mongolia.
METHODS. The clinical records of first 121 cases patients who had microvascular reconstruction done between 2011 and 2017 were reviewed. The indications for surgery, choice of flap, duration of surgery and flap survival were noted.
RESULTS. Our study were performed on 121 cases, among them 84.3% flaps were survived, most of defects occurred following cancer resection. Anterolateral thigh and radial forearm flaps were performed commonly for our reconstruction surgery.
CONCLUSION. 84.3% free flap recorded success rate indicates our early experiences. Although the National Medical University do not have postgraduate reconstructive and plastic surgical training, we believe that meticulous planning, careful vessel selection, close flap monitoring as well as improved infrastructural support can lead us to much better success rates of microvascular reconstruction in our country.
2. EPIDEMIOLOGIC STUDY OF ORAL AND MAXILLOFACIAL SURGERY PATIENTS IN MONGOLIA
Davaadorj P ; Otgonbileg E ; Bold M ; Odkhuu J ; Purevdorj G ; Denis S ; Ayanga G ; Khuderchuluun CH ; Batbayar B ; Baasanjav N ; Oyunaa CH ; Budmaa S ; Khentii L
Innovation 2015;9(Dentistry):16-20
The purpose of this study was to analyze the epidemiology of oral and maxillofacial surgery patients in Mongolia and advocate guidelines and programs to promote optimal oral health care. A fact-finding epidemiologic study on the patients who visited at Departments of Oral and Maxillofacial Surgery, at National Hospitals at Ulaanbaatar city and Province and other Central hospitals of Mongolian, from Jan to Dec, 2013.Total 12957 patients treated at inpatients care center at the above mentioned national hospitals. From Ulaanbaatar city were 4284 (36%) and from province were 7673 (64%). Patients from province were treated at FCH 69%, NTORC 6.4%, NCC 11.3%, NCMCH 27% and CMAFH 1.8%. Zero to 16 years, 17 to 36 years, 37 to 56 years and 57 or more years old patients were3072 (27.1%), 4224 (34.2%), 3218 (26.9%) and 1412 (11.8%), respectively. Males and females were 6841 (53%), 6090 (47%). Cases of the inpatients were as follows: infectious disease 5971 (49.88), benign tumor 1039 (8.01%), trauma & injury 1799 (15%), salivary gland disease 2.41%, TMJ disease 2.8%, neuralgia and muscle pain 0.8% and others. 5 provinces have no Oral and Maxillofacial Surgeon and patients were referred to other central hospitals or to the Ulaanbaatar city. This study gives a topic of conversation about undergraduate dental education, continuing education and enough specialists in the region.
3.Association of Lipids, Lipoproteins, and Apolipoproteins with Stroke Subtypes in an International Case Control Study (INTERSTROKE)
Martin J. O’DONNELL ; Matthew MCQUEEN ; Allan SNIDERMAN ; Guillaume PARE ; Xingyu WANG ; Graeme J. HANKEY ; Sumathy RANGARAJAN ; Siu Lim CHIN ; Purnima RAO-MELACINI ; John FERGUSON ; Denis XAVIER ; Liu LISHENG ; Hongye ZHANG ; Prem PAIS ; Patricio LOPEZ-JARAMILLO ; Albertino DAMASCENO ; Peter LANGHORNE ; Annika ROSENGREN ; Antonio L. DANS ; Ahmed ELSAYED ; Alvaro AVEZUM ; Charles MONDO ; Conor JUDGE ; Hans-Christoph DIENER ; Danuta RYGLEWICZ ; Anna CZLONKOWSKA ; Nana POGOSOVA ; Christian WEIMAR ; Romana IQBAL ; Rafael DIAZ ; Khalid YUSOFF ; Afzalhussein YUSUFALI ; Aytekin OGUZ ; Ernesto PENAHERRERA ; Fernando LANAS ; Okechukwu S. OGAH ; Adesola OGUNNIYI ; Helle K. IVERSEN ; German MALAGA ; Zvonko RUMBOLDT ; Shahram OVEISGHARAN ; Fawaz AL HUSSAIN ; Yongchai NILANONT ; Salim YUSUF ;
Journal of Stroke 2022;24(2):224-235
Background:
and Purpose The association of dyslipidemia with stroke has been inconsistent, which may be due to differing associations within etiological stroke subtypes. We sought to determine the association of lipoproteins and apolipoproteins within stroke subtypes.
Methods:
Standardized incident case-control STROKE study in 32 countries. Cases were patients with acute hospitalized first stroke, and matched by age, sex and site to controls. Concentrations of total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein A1 (apoA1), and apoB were measured. Non-HDL-C was calculated. We estimated multivariable odds ratio (OR) and population attributable risk percentage (PAR%). Outcome measures were all stroke, ischemic stroke (and subtypes), and intracerebral hemorrhage (ICH).
Results:
Our analysis included 11,898 matched case-control pairs; 77.3% with ischemic stroke and 22.7% with ICH. Increasing apoB (OR, 1.10; 95% confidence interval [CI], 1.06 to 1.14 per standard deviation [SD]) and LDL-C (OR, 1.06; 95% CI, 1.02 to 1.10 per SD) were associated with an increase in risk of ischemic stroke, but a reduced risk of ICH. Increased apoB was significantly associated with large vessel stroke (PAR 13.4%; 95% CI, 5.6 to 28.4) and stroke of undetermined cause. Higher HDL-C (OR, 0.75; 95% CI, 0.72 to 0.78 per SD) and apoA1 (OR, 0.63; 95% CI, 0.61 to 0.66 per SD) were associated with ischemic stroke (and subtypes). While increasing HDL-C was associated with an increased risk of ICH (OR, 1.20; 95% CI, 1.14 to 1.27 per SD), apoA1 was associated with a reduced risk (OR, 0.80; 95% CI, 0.75 to 0.85 per SD). ApoB/A1 (OR, 1.38; 95% CI, 1.32 to 1.44 per SD) had a stronger magnitude of association than the ratio of LDL-C/HDL-C (OR, 1.26; 95% CI, 1.21 to 1.31 per SD) with ischemic stroke (P<0.0001).
Conclusions
The pattern and magnitude of association of lipoproteins and apolipoproteins with stroke varies by etiological stroke subtype. While the directions of association for LDL, HDL, and apoB were opposing for ischemic stroke and ICH, apoA1 was associated with a reduction in both ischemic stroke and ICH. The ratio of apoB/A1 was the best lipid predictor of ischemic stroke risk.