Objective:To investigate the change characteristics of SCP/DCP blood flow density and FAZ in retina of patients with acute central serous chorioretinopathy (CSC).Methods:The clinical data of 45 patients(45 eyes) with acute CSC in our hospital from January 2017 to October 2019 were retrospectively analyzed.All patients included 45 lesion eyes and 45 healthy eyes were set as lesion eye group and healthy eye group respectively, and 30 healthy people with 30 eyes were set as control group.The FAZ, blood flow density, CMT and SFCT of different groups were compared, and the enhanced morphology of capillary blood flow was analyzed.Results:There was no statistically significant difference in FAZ level in SCP among the three groups( P>0.05). The FAZ in DCP of the lesion eye group[(0.81±0.19)mm 2] was significantly higher than that in the healthy eye group [(0.43±0.12)mm 2] and the control group [(0.38±0.08)mm 2]( t=3.17, 3.22, all P<0.05). The blood flow density in the SCP/DCP of the lesion eye group and healthy eye group were significantly lower than those in the control group( t=2.69, 3.01, all P<0.05). The levels of CMT and SFCT in the lesion eye group [(427.43±35.66)μm and (359.43±32.95)μm] were significantly higher than those in the healthy eye group [(276.35±17.02)μm and (260.38±25.66)μm] and the control group [(285.69±11.47)μm and (235.76±20.50)μm] ( t=8.17, 9.89; 10.26, 15.92; all P<0.05). There was no statistically significant difference in CMT level between the healthy eye group and the control group( P>0.05). The level of SFCT of the healthy eye group was significantly higher than that in the healthy eye group and control group( t=4.39, P<0.05). The results of optical coherence tomography showed that the local enhancement of capillary blood flow was seen in 23 eyes, and the diffuse enhancement of blood flow was seen in 22 eyes in the affected eye group, and there was subretinal effusion at the same time.In the healthy eye group, the signal changes of capillary strength and intensity were seen.In the control group, there was no significant change. Conclusion:The results of OCTA showed that in lesion eye group, local enhancement of capillary blood flow was seen in 23 eyes and diffuse enhancement of blood flow was seen in 22 eyes, and subretinal effusion was all found.In healthy eye group, even strong and weak signal changes of capillary were seen, while there were no above changes in control group.

AIM:To investigate the influencing factors of abnormal telangiectasia secondary to diabetic retinopathy(DR).METHODS: Prospective studies. A total of 153 cases(240 eyes)with DR treated in our hospital from January 2021 to January 2023 were selected to analyze the risk factors of abnormal telangiectasia secondary to DR and its predictive efficacy.RESULTS: The patients were divided into dilated group(77 eyes of 40 cases)and non-dilated group(163 eyes of 113 cases)according to whether they had secondary abnormal telangiectasia. There were significant differences in diabetic macular edema, hard exudates grade and fasting blood glucose level between the two groups(P<0.05). Logistic regression analysis showed that diabetic macular edema, high hard exudates grade and high blood glucose level were the risk factors for abnormal telangiectasia secondary to DR(P<0.05).CONCLUSION: The occurrence of telangiectasia secondary to DR may be related to diabetic macular edema, grade 3 hard exudates and high blood glucose level.