Objective To study the efficacy and safety of endoscopic submucosal dissection ( ESD ) for colorectal neuroendocrine tumor .Methods Clinical data of 43 cases of colorectal neuroendocrine tumor receiving ESD therapy from Sep .2010 to Feb.2014 were retrospectively analyzed , and the safety and efficacy were evalua-ted.Results All the 43 cases received ESD therapy , among whom 2(4.65%)cases developed delayed bleeding and recovered after endoscopic treatment .No perforation was found .4 cases had high fever and recovered after antibiotic treatment.One case(2.33%)of recurrence was found by colonoscopy 1 year later, and underwent sur-gery.The other 42 cases were followed up for 6 months to 2 years, during which no recurrence or metastasis was found.Conclusion ESD is a simple, safe and effective modality for colorectal neuroendocrine tumor .

OBJECTIVETo compare the applicative effect of four diagnostic criteria of metabolic syndrome (MS) among the urban adult population of Zhejiang Province.

METHODSAccording to multi-stage stratified and proportional to size, cluster, random sampling principle, 3 417 adults population at urban areas were extracted by random number method from 320 families of Shangcheng and Jianggan community in Hangzhou,Jiangdong community in Ningbo and Wucheng community in Jinhua in 2009 and 2010 respectively, which excluded pregnant, wet nurse, children, and those who were at least 18 years of age. Height, weight, waist, blood pressure, fasting plasma glucose (FBG) , 2-hour postprandial blood glucose (2h-PBG), TG and HDL-C of all the subjects were measured by standard method. MS was diagnosed and compared according to four diagnostic criteria:Chinese Medical Association Diabetic Society (CDS), Joint Committee for Developing Chinese Guidelines (JCDCG), American National Cholesterol Education Program Adult Treatment PaneI II in 2005 (ATPIII) and International Diabetes Federation (IDF), respectively.

RESULTSThe high prevalence of MS diagnosed by the criteria of ATPIII was 21.6% (737/3 417) , while the lowest prevalence diagnosed by CDS was 9.8% (335/3 417), the result of consistency check demonstrated the MS diagnostic criteria of ATPIII and IDF, ATPIII and JCDCG were in strong and the same accordance with the concordance rate, Kappa value was 0.75, while the consistency of the criteria of ATP III and CDS were in relatively weak agreement, Kappa value was 0.53; the detection result of MS abnormal components showed the highest proportion of having ≥ 3 risk factors was presented by ATPIII among subjects diagnosed as MS (100.0%) , meanwhile, the lowest proportion of having ≥ 3 risk factors was also found by ATPIII among those MS-free (0.8%) .

CONCLUSIONSThe criteria of ATPIII may have more sensitivity when screening MS and its abnormal components.However, it's limited to extrapolate the results from the cross-sectional survey to the total population.

Adult ; Blood Glucose ; Body Weight ; Body Weights and Measures ; Cholesterol ; Cross-Sectional Studies ; Diabetes Mellitus ; Diagnostic Techniques and Procedures ; Humans ; Metabolic Syndrome ; Prevalence ; Risk Factors ; Urban Population

Oxidation stress is a key factor in the progression of various diseases.Hydrogen,as a reducing inert gas,can effectively inhibit the reactive oxygen produced by oxidative stress.With the daily use of dissociated water in recent years,the health care and treatment effects of hydrogen rich water are gradually reflected and valued.In this paper,the current status of hydrogen in medical research is briefly reviewed,which provides a reference for reducing the damage caused by the increase of reactive oxygen species in the treatment process and the wide application of hydrogen as a safe oxidant in the future.