1.Study of high-field MRI in primary hepatic carcinoma capsule
Xiaobiao ZHANG ; Yulin GUO ; Ting LI ; Hua HE ; Lei CAI ; Denghua HOU
Journal of Practical Radiology 2014;(4):627-630,648
Objective To analyze and compare the advantages and disadvantages in high-field MRI scan and LAVA enhanced in the display of hepatic carcinoma capsule,in order to improve the early diagnosis and differential diagnosis level of primary hepatic carcinoma by MRI.Methods MRI data of 233 patients of primary hepatic carcinoma were retrospective analysed by two radiologists. Results 233 cases of primary hepatic carcinoma,except for 18 cases of diffuse hepatocellular carcinoma,a total of 239 lesions (54 small hepatocellular carcinoma,76 nodular hepatocellular carcinoma,109 massive hepatocellular carcinoma )were found .Hepato-cellular carcinoma capsule display rate was 139/239(58.16%).119 T1 WI,87 cases were found in T2 WI,and 139 cases were found in LAVA enhanced scan.25 lisions showed complete capsule on T1 WI,12 lisions showed complete capsule on T2 WI,59 lisions showed complete capsule on LAVA enhanced scan.Small hepatocellular carcinoma displayed capsule 21/54 (38.9%),nodular hepa-tocellular carcinoma 53/76 (69.7%),massive hepatocellular carcinoma 65/109 (59.6%).Conclusion High-field MRI conventional scan and LAVA enhenced scan can display PHC capsule better,LAVA enhanced (portal phase + delay phase)showed PHC capsule better than T1 WI and T2 WI.
2.Value of diffusion-weighted imaging and apparent diffusion coefficient in the diagnosis and differential diagnosis of prostate cancer
Zhiqiang CHEN ; Wenjun YANG ; Yulin GUO ; Fubao CHEN ; Lei CAI ; Denghua HOU ; Wei ZHANG ; Ningfu LI ; Jianguo ZHAO ; Kai ZHU
Chinese Journal of Geriatrics 2011;30(3):216-219
Objective To explore the application of diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) value in the diagnosis and differential diagnosis of prostatic cancer. Methods Diffusion-weighted echo-planar imaging (EPI) sequences were performed in 46 patients, including 21 cases of benign prostatic hyperplasia (BPH), 9 cases of chronic prostatitis and 16 cases of prostate cancer. DWI were obtained with a b-factor of 800 s/mm2. According to the pathological results obtained by ultrasound guided biopsy, the peripheral zone of prostate was divided into six parts by orientations and they were divided into noncancerous, hyperplasia, prostatitis and cancerous groups. The ADC value of each region was measured and analyzed with one-way ANOVA and ROC analysis. Results Acceptable images for ADC measurement were obtained in all cases.The mean ADC values of prostatic peripheral zone, prostatic central gland, inflammatory area and cancerous area were (2.20±0. 29)×10-3 mm2/s, (1.66±0.14)×10-3 mm2/s, (1.95±0.34)×10-3 mm2/s and ( 1.24 ± 0.32) × 10-3 mm2/s, respectively. There were statistically significant differences in ADC values between the inter-groups (P<0. 01 ). With ROC cut point setting to 1.49 ×10-3 mm2/s, the diagnostic sensitivity and specificity for prostate cancer were 86. 8% and 94. 0%, the area under the ROC curve (AUC) was 0. 945±0. 010. Conclusions ADC value might be useful to evaluate prostate cancer. DWI has an important clinical application value in the diagnosis and differentiation of prostate cancer.
3.A finger-taping switch task functional magnetic resonances imaging study in the patients with Tourette's syndrome
Bo YANG ; Guiping LI ; Jinshan ZHANG ; Xiangquan KONG ; Haibo XU ; Lin MA ; Huiyi YE ; Youquan CAI ; Yuangui GAO ; Denghua LIU
Chinese Journal of Neurology 2012;45(8):600-604
ObjectiveTo investigate the central nervous system mechanisms of active of movement switch in the patients with Tourette' s syndrome( TS),and to explore the possible underlying distinct neural networks for tic trigger and generation. Methods Participants were 14 patients with TS and 14 age- and gender-matched healthy volunteers with no history of physical,psychiatric or neurological disease: All patients were assessed with functional magnetic resonances imaging (fMRI)of the brain during the intermittent performance of finger-tapping switch tasks,Blood-oxygen-level dependent-fMRI was performed using a 3.0 Tesla MR.The area over which the activation was distributed was calculated,and the activation volumes were also compared between the patients with TS and the control subjects.ResultsThe regions activated in the patients with TS and in the volunteers were similar in several brain regions,including contralateral precentral and postcentral gyrus,contralateral mesia pre-front gyrus,contralateral cingulate gyrus,contralateral insula and ipsilataral cerebellum. There were also many different activation areas between the patients and the control subjects. The patients with TS demonstrated more significant and extended activation in the contralateral pre- and postcentral gyrus than the healthy volunteers.The volume of the left pre- and postcentral gyrus of the TS patients was (8.024 ±0.071 ) cm3,while the volume of the left pre-and postcentral gyrus of the control subjects was ( 6.480 ± 0.026) cm3 ( t =3.026,P < 0.01 ) ; The volume of the right pre- and postcentral gyrus was (6.192 ± 0.019) cm3 in the TS cases,while there was (5.608 ±0.037) cm3 in the control subjects (t =2.752,P <0.05).There were significant differences in the volumes of bilateral pre- and postcetral gyrus between the TS and control subjects. The activations of conralateral thalamus without contralateral insula were found in the patients with TS. Conversely, the contralateral insula activation without thalamus activation could be found in the healthy volunteers.ConclusionThe thalamus might play an important role in the aetiological and physiopathologic mechanisms of the TS. The thalamus along with the parietal cortex,cingulate cortex and insular cortex appear to constitute a distinct neural network for tic trigger and generation.
4.Application of selective arterial embolization in the iatrogenic hemorrhage
Mengdi LI ; Yong CHEN ; Zhiling GAO ; Ecai XUE ; Jing MA ; Denghua HOU ; Lei CAI ; Bing CHEN ; Yulin GUO
Journal of Practical Radiology 2014;(11):1886-1889
Objective To investigate the clinical application value of selective arterial embolization in the treatment of iatrogenic hemorrhage.Methods 32 cases with iatrogenic hemorrhage were retrospectively analyzed.The location and feature of bleeding were identified by selective percutaneous artery angioraphy,and then super-selective interventional embolization were performed.The embolic agents inclued gelfoam medical line,steel coils or polyvinyl alcohol (PVA)particles.Results In 32 patients,26 cases with active bleeding signs were found by angiography,they mainly presented contrast medium overflow,6 cases with pseudo-aneurysms,1 case with ar-teriovenous fistula.All patients underwent interventional embolization successfully.Only 1 case underwent twice procedure because of rehaemorrhagia on the 8 days after embolization.Follow-up for a month after arterial embolization,25 cases had no severe compli-cations,1 case died by multiple organ failure.In 6 negative cases,3 cases died by hemorrhagic shock,3 cases stopped hemorrhage after medical treatment.Conclusion Selective angiography is a safe and effective measure for the treatment of iatrogenic hemor-rhage.
5.The value of ultraGlarge pitch Turbo Flash scan mode in the diagnosis of tracheal foreign body in infants
Hui SONG ; Wenhang LI ; Ying TANG ; Rongpin WANG ; Lei TANG ; Denghua CAI ; Xianchun ZENG
Journal of Practical Radiology 2019;35(10):1661-1664
Objective To explore the value of ultra-large pitch Turbo Flash scan mode in the diagnosis of tracheal foreign body in infants.Methods The imaging data of 60 infants with foreign body in trachea confirmed by bronchus endoscopy were analyzed retrospectively. The 60 infants were equally divided into 2 groups according to the scanning time.For group A,the routine scan with the mode of CARE Dose 4D/CARE kV and pitch as 1.9 was performed.For group B,the scan with ultra-large pitch Turbo Flash model was performed.The scanning time,volume CT dose index (CTDIvol)and dose length product (DLP)of each patient were recorded in both groups and statistically analyzed.Results The scanning time,DLP and CTDIvol of group A and group B were statistically significant.CTDIvol and DLP of group B were significantly lower than those of group A (P<0.05).The diagnostic accuracy of group A and B were 100%(30/30),respectively (P>0.05).The foreign body display of group A and B were 100% (30/30),respectively (P>0.05).Conclusion Ultra-large pitch Turbo Flash can be used to detect tracheal foreign body in infants.It can significantly reduce radiation dose,shorten examination time and obtain satisfactory image quality.