1.Peripheral contrast-enhanced MRA at open-bore 3 T, with low dose contrast agent
Dan LI ; Kexue DENG ; Jiang LIN
Acta Universitatis Medicinalis Anhui 2015;50(9):1333-1336
Objective To investigate the feasibility with low dose contrast agent in patients undergoing peripheral magnetic resonance angiography with high spatial resolution at open-bore 3 T scanner. Methods Images of MRA were assessed separately by two radiologists. And the images of DSA were assessed by one radiologist. The degree of the two interobservers' consensus for detection of arterial stenosis was determined by calculating the Kappa coef-ficient. Spearman rank correlation coefficient was used for revealing the relationship between contrast-enhanced MR angiography and DSA,in terms of categories of stenosis. Results For the degree of vessel stenosis, Cohen' s statis-tics revealed excellent agreement between the two observers. There was a significant correlation between DSA and MRA(P<0. 05). Conclusion At this open-bore 3 T scanner, high spatial resolution peripheral magnetic reso-nance angiography is achieved with low dose contrast agent.
3.Comparative analysis of modified instruments and conventional instruments in transumbilical single-pore laparoscopic cholecystectomy
Lin′an WANG ; Douxing DENG ; Yuming LI ;
Chinese Journal of Postgraduates of Medicine 2016;(2):128-131
Objective To analyze the effect of clinical application of transumbilical single-pore laparoscopic cholecystectomy with modified instruments and conventional instruments. Methods Fifty transumbilical single-pore laparoscopic cholecystectomy patients with conventional instruments (conventional instruments group) and 50 transumbilical single-pore laparoscopic cholecystectomy patients with modified instruments (modified instruments group) were selected. The operation time, recovery satisfaction degree of navel incision, intraoperative bleeding, postoperative complication, change rate of surgical procedure, length of hospital stay and hospitalization expenses were compared between 2 groups. Results The operation time and change rate of surgical procedure in modified instruments were significantly lower than those in conventional instruments, and the recovery satisfaction degree of navel incision was significantly higher than that in conventional instruments:(43.5 ± 12.0) min vs. (60.0 ± 2.2) min, 2.0% (1/50) vs. 12.0% (6/50) and (4.5 ± 0.2) scores vs. (3.2 ± 1.2) scores, and there were statistical differences (P<0.05). There were no statistical differences in intraoperative bleeding, postoperative complication, length of hospital stay and hospitalization expenses between 2 groups (P>0.05). Conclusions The transumbilical single-pore laparoscopic cholecystectomy with modified instruments can obviously reduce the operation time and the change rate of surgical procedure, improve the recovery satisfaction degree of navel incision, reduce the operation difficulty of performer and shorten the time of learning curve.
4.Study on the quality standard for Yinchai Granules
Lin DONG ; Yi LI ; Xiaohong DENG
Chinese Traditional Patent Medicine 1992;0(01):-
AIM: To establish the quality standard for Yinchai Granules (Caulis Lon icerae, Radix Bupleuri, Folium Eriobotryae, etc). METHODS: TLC was used to identify Radix Bupleuri, Folium Eriobotrya e and HPLC to determinate the chlorogenic acid content was determined by HPLC. RESULTS: The linear range of chlorogenic acid was 23.64~378.24ng, r=0.9999, respectively. The average recovery was 99.14%. CONCLUSION: The method is simple. The result is accurate and the reproducibility is good and can be used as the quality control of Yin chai Granules.
5.Protective effects of mycelium of cultured Cordyceps sinensis on testis in diabetic rats
Zhihong DENG ; Xiaoyan LIN ; Weimin LI
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
Objective To observe the protective effects of mycelium of cultured Cordyceps sinensis on testis in diabetic Wistar rats. Methods 21 rats were divided into control group(C), diabetes group(D) and treatment group (T) at random. Diabetic model was reproduced by intraperitoneal injection of alloxan. After having been treated with Jinshuibao capsule for 8 weeks, serum levels of glucose, insulin, testosterone and levels of high energy phosphate compound, MDA, SOD, GSH-Px, and ATPases in the testis were determined respectively. Results Compared with control group, testicular mitochondria showed lipid peroxidase injury, with disturbed energy metabolism, and the activity of ATPases was lowered. All the changes in serum and testes were improved when Jinshuibao capsule was given. Conclusion Mycelium of cultured Cordyceps sinensis might have protective effects on the testis in diabetic Wistar rats.
6.Outcome of the Orientation and Mobility Skills Training Projects in Yunnan
Meihua LI ; Yikun LIN ; Qiang DENG
Chinese Journal of Rehabilitation Theory and Practice 2007;13(5):473-474
Objective To survey the outcome of the Orientation and Mobility (O&M) Skills Training projects, a communities based rehabilitation which was advancing in Yunnan. Methods 310 blind subjects in model areas were assessed with the Assessment Standard of O&M Training for the Blind. Results 98.7% of subjects improved their mobility skills after receiving O&M skills training, that was 44.5% could walk independently in short distance, 34.5% in long distance, and 19.7% in complex surroundings in detail. There was no difference (P>0.05) among the different gender, educated level, and visual loss level, however, there was significant difference (P<0.05) made by the age level and the causes of disability of vision. Young and middle-aged subjects have better training result than the aged, as well as the congenital blind ones than the postnatal ones. Conclusion O&M skills training in Community Based Rehabilitation Services is effective for visual rehabilitation.
7.Application of mind map in community health education of rheumatoid arthritis patients
Li LI ; Lin LONG ; Ji GUAN ; Hongmei TIAN ; Li DENG
Chinese Journal of Medical Education Research 2014;(9):958-962
Objective To evaluate the application effects of mind map in community health education of rheumatoid arthritis patients. Methods 65 rheumatoid arthritis patients from Shunqing district of Nanchong City, Sichuan Province were randomly divided into an observation group (n=33) and a control group(n=32). Both groups received six-month health education. Health educators utilized mind map for the observation group and traditional health education for the control group. Before and after implementation, the two groups' mastery of disease knowledge was compared. During the period of 1, 3, 6 months, two groups received compliance evaluation respectively. During the study period, a questionnaire was given to the observation group to collect their attitude towards the mind map health education and their evaluation about it. Measurement data was represented by x ± s, using group t-test design information and single-sample t-test. χ2test was used in the count data for compar-ison between groups with test levelα=0.05. Results The scores of disease knowledge were as follows. Before implementation there was no statistically significant difference between two groups (P=0.921);After implementation, the score of observation group was(19.97±3.03), while the score of control group was(17.59±3.11), the difference was statistically significant(t=3.122,P=0.003). The difference of 1,3,6-month compliance scores was statistically significant(t=2.173,P=0.034;t=2.371,P=0.021;t=2.615,P=0.011) with the observation group's scores(18.24±3.44),(18.94±3.25),(19.64±3.06) respectively,and the control group's scores(16.47±3.13),(16.97±3.45),(17.44±3.70). Observation group's attitude questionnaire scores of each project are > 3, and there was significant difference be-tween two groups (P=0.000). Conclusion Mind mapping method can be used in community health education for rheumatoid arthritis patients to help patients master the knowledge of the disease and improve the compliance. Its effect is better than traditional methods.
8.Application of ultra-pulse CO2 laser in blepharoplasty
Ping CHEN ; Yongxuan LI ; Lin DENG ; Bilai LIU ; Baomiao LI
Chinese Journal of Medical Aesthetics and Cosmetology 2009;15(3):159-161
Objective To explore the applied values of ultra-pulse CO2 laser in blepharoplasty by shortening procedure time, improving the surgical satisfactory result and alleviating the operative and postoperative hemorrhage. Methods 238 patients with bulging, redundant skin in the upper and lower eye lids, including brow lift (26 cases), double eye lid surgery (48 cases), and lower lash line incision (159 cases). Laser incision was implemented with the ultra-pulse CO2 laser system. Results Bleeding was scant in 238 cases and hence local swelling subsided quickly with excellent healing. No eetropion, he-matoma and diplopia ever occurred. 3 months to 3 years follow-up showed satisfactory for all the patients. The result was quite satisfied in clinical observation and postoperative follow-up. Conclusion Utilizing the ultra-pulse CO2 laser in blepharoplasty has confirmed the satifisfatory surgical results, decreasing the surgical time, and reducing the intraoperative and postoperative bleeding.
9.Impacts of high-altitude training on self-organizing adaptation in swimming athletes before competition: analysis with compressed spectral array electroencephalogram
Liya LIN ; Li ZHANG ; Shuxun DENG ; Jie LI
Chinese Journal of Tissue Engineering Research 2005;9(40):176-179
BACKGROUND: High-altitude training before competition aims to obtain maximum hypoxia physiological adaptability of athletes through hypoxia environmental irritation at high altitude. Physiological adaptability to high al titude is the substantial foundation for function improvement of athletes,reflecting adjustment of body to environmental changes.OBJECTIVE: In views of self-regulation, practical training and compressed spectral array (CSA) electroencephalogram (EEG), and by observing adaptive change rule of brain before (before competition) and after high-altitude training of swimming athletes, the influence of high-altitude training was analyzed systematically on self-organizing state of athletes before competition so as to probe into the impacts of high-altitude training from brain level.DESIGN: Randomized investigation.SETTING: Guangdong Scientific Institute of Physical Exercise and Physical Exercise College of South China Normal University.PARTICIPANTS: Nine swimming athletes were selected from Guangdong Swimming Team from March to April 2001.METHODS: Time-order observation was applied in the experiment, in which, the results 1 week (3rd March) before high-altitude training, during (22nd March) and on the 5th day (5th April) after the training, the results in competition on the 13th day (12th April) after high-altitude training and corresponding blood lactic acid were tested and SCA EEG was done successively one day before high-altitude training (10th March), on the 1st day after the training (30th March) and on the 11th day after training, that was two days before National Competition (10th April) to observe self- adaptive regulation of brain to sports training load.MAIN OUTCOME MEASURES: ① Training index and lactic acid change before and during high-altitude training and before competition. ②Comparison of results before high-altitude training and in competition. ③Changes in indexes of cerebral evaluation before, during and after high-altitude training and before competition.RESULTS: ① Training results were changeable in high-altitude training.In national competition after high-altitude training, the scores of 6 cases of 10 person-times were reduced. Changes in blood lactic acid after high-altitude training were in conformity with training results. ② After high-altitude training, the average frequency of brain information distribution in athletes was shifted towards high frequency. Before the competition, negative entropy was lessened and information entropy was dispersed and the score in competition was declined.CONCLUSION: ① Cerebral order parameters of athletes constitute multicentralization, form the dispersion of technique control information and result in re-adjustment of brain function at matrix coordinating level, suggesting declining capacity to athletics. ② Effects of high-altitude training and maintaining of its functions are based on coincidence and continuity of arrangement of rise-fall training intensity of individual state and on the recovery and maintaining of the intensity at flatlands.
10.Observation on the Clinical Efficacy of Cancer-linked Hyperhidrosis with Neuropad Diagnostic Patches
Yuren LIN ; Liqun JIA ; Liya LI ; Bo DENG ; Peiwen LI
International Journal of Traditional Chinese Medicine 2009;31(6):497-498
Objective To observe the clinical efficacy of applying Sweat Reduction Formula (SRF) externally in the treatment of cancer-linked hyperhidrosis. Methods 45 tumor patients, who exhibited excessive perspiration, were selected and recruited randomly into an experimental group (Sweat Reduction Formula group) with 24 patients in it and a control group (Placebo group) with 21 patients in it. The experimental group was treated with SRF and the control group was administrated with placebo. Neuropad diagnostic patches were used to observe the period of time that required for any visual changes in color before and after medication. These observations were then matched with the commonly seen signs and symptoms scoring table, to evaluate the changes of symptoms and KPS. Results The color changing time of the experimental group was 14.45±3.91 min. and 19.51±5.30 min. before and after medications respectively. And the changing time in the control group was 13.49±4.96 min. After medication. The results were highly significant with P<0.05. There were also different levels of significant improvements in terms of spontaneous perspiration, night sweating, dry mouth, feverish sensation over hand-foot centers and body, aversion to cold etc after the treatment in the experimental group. Conclusion It would be more objective to evaluate the clinical efficacy of applying SRF on navel to treat cancer-linked hyperhidrosis with neuropad diagnostic patches.