2. Solitary fibrous tumors: Imaging features and differentiation between benign and malignant tumors
Tumor 2013;33(5):454-459
Objective: To investigate the clinical and pathological features and imaging manifestations of SFT (solitary fibrous tumor), and further to define the differiciation between the benign and malignant SFTs. Methods: The imaging findings were retrospectively analyzed and compared with the corresponding pathological results in 18 patients with SFT confirmed pathologically. Results: Of the 18 patients, 2 had postoperative recurrent or metastatic tumor, 3 had malignant SFT. The X-ray and MSCT (multi-slice computed tomography) scan images showed oval or lobulated masses with discrete margins except one malignant tumor. The tumor density was clear or nearly uniform. MRI (magnetic resonance imaging) examination showed that the tumors had intermediate signal intensity on T1WI (T1-weighted image) and heterogeneous signal intensity with flow voids on T2WI (T2-weighted image). All tumors showed heterogeneously intermediate or intense enhancement with geographic pattern. Intralesionally and paraleisonally prominent feeding vessels could be seen. The results of immunohistochemistry demonstrated that CD34 was positive in 18 patients; Bcl-2 and vimentin were positive in 17 patients; S100 was negative in 15 patients; cytokeratin and desmin were negative in 18 patients; Ki-67 expression was less than 5% in 15 benign tumors and more than 5% in 3 malignant tumors. Conclusion: There are some specific imaging features which are helpful to the differential diagnosis for SFT. These specific imaging features include the rich feeding vessels, the signal intensity on T2WI and the different enhancements associated with the tissue compositions of the tumor. However, making a definitive diagnosis still depends on pathology and immunohistochemistry. Copyright © 2013 by TUMOR.
3.Protease-activated receptors in periodontitis.
Xia QI ; Ling-xue KONG ; Meng DENG
Chinese Journal of Stomatology 2012;47(12):764-767
Animals
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Cardiovascular Diseases
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etiology
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metabolism
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Humans
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Inflammation
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metabolism
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Periodontitis
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complications
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metabolism
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microbiology
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Platelet Aggregation
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physiology
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Porphyromonas gingivalis
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pathogenicity
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RNA, Messenger
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metabolism
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Receptor, PAR-1
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metabolism
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Receptor, PAR-2
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genetics
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metabolism
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Receptors, Proteinase-Activated
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metabolism
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Receptors, Thrombin
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metabolism
4.A systematic review of the long-term stability of the hard tissue of skeletal classⅢmalocclusion after ortho-dontic combined surgical treatment
Ling LIU ; Mengxuan DENG ; Xiaoping YUAN
Journal of Medical Postgraduates 2015;(5):510-516
[Abstract ] Objective The orthodontic-surgery is the most effective way to treat the severe skeletal class Ⅲmalocclusion,but the long-term stability is still disputed .The aim of this systematic review is to analyze the long-term stability of hard tissue of seriously skeletal Class Ⅲ malocclusion patients treated with orthodontic combined surgical treatment . Methods Literature were searched through the Cochrane Central Register of Controlled Trials , Cochrane Library, Medline via pubmed (1950-2014), EMBASE (1980-2014) and other foreign databases , and Chinese Biomedical Literature Database , China National Knowledge Infrastructure Database , VIP Database for Chinese Technical Periodicals , digital journal of Wan fang Data and so on .Unpublished conference papers and gray litera-tures were collected manually .The literatures consist of randomized controlled trials ( RCT) , quasi-randomized controlled trials and clini-cal case-control trial (CCT) were selected.Then meta analysis was performed for annexable literatures and qualitative description was performed for diverged documents . Results Five foreign articles and 1 Chinese article suitable for analysis were ultimately studied . All the studies were CCT and a total of 260 patients were involved in the present systematic review .Meta analysis showed that the SNA , SNB, ANB, MP SN and Y-axis did not change significantly during 3 years after operation (P>0.05) and a good skeletal class I facial types were maintained .The comparison results of MP-SN and Y-axis showed that there was no significant statistical difference and the mandibular plane angle maintained the relative stability .Meta analysis was not performed because of the different measurement methods of A, B, Pg and Ramus inclination , so the qualitative description was used .Point A and Ramus inclination remained relatively stable posi-tion, but point B and Pg had some replace compared with post-operative. Conclusion The orthodontic and surgical treatment for skeletal classⅢmalocclusion could keep the hard tissue relative stabil-ity except a little replace of the mandibular .
5.Analysis of the status quo of pediatric nursing post setting of 7 hospitals
Juan DENG ; Ling FAN ; Linlin XING
Chinese Journal of Practical Nursing 2015;31(4):291-294
Objective We tried to investigate the current status of pediatric nursing post setting and analyze the practical application effect in the clinical working practice for the foundation of readjusting and setting up the pediatric nursing positions.Methods By convenient sampling method,the general condition and current post setting situation in the pediatric wards of 7 hospitals with self-designed questionnaires were investigated.The results underwent analysis Results The nursing post setting in pediatric wards of 7 hospitals were not all the same,nursing posts in the pediatric ward included three categories:management positions,teaching positions and clinical positions.Management positions included the head nurse,deputy head nurse and head nurse assistant; teaching positions included the teaching secretary and clinical total teaching nurse; the seven kinds of clinical nursing positions were office job,day shift,night shift,evening shift,midnight shift,late-morning shift,auxiliary job.Though some nursing jobs differed in the position names and working hours,their job contents were nearly identical.Conclusions Pediatric nursing post setting management in our country is still in the exploratory stage at present,it has not form a unified perfect job management system.Pediatric nursing positions should be set from the perspective of evidencebased theory,satisfying the demands of patients as the guidance,coming from clinical needs as the first principle,in the full implementation of the accountability for nursing and based on comprehensive consideration of various factors,so that the post setting can be scientific and reasonable.
6.The training of clinical thinking ability in obstetrical teaching for medical students in eightyear program
Ni DENG ; Ling WU ; Hongying HOU
Chinese Journal of Medical Education Research 2011;10(10):1173-1175
The training of clinical thinking ability is the key point of obstetrical teaching to medical students in eight-year program.Obstetrical department of the third affiliated hospital of Sun Yat-sen university has put forward specific methods of SP inquiring and PBL case analysis teaching.The well-designed teaching methods have an active role in the training of case history collecting ability,diagnosing and treating ability to medical students in eight-year program.
7.Study on construction of teaching quality management system in medical colleges under per-spective of teaching total quality management
Bing JIA ; Fengyan JIANG ; Ling DENG
Chinese Journal of Medical Education Research 2013;(8):845-849
According to the current problems in the management of teaching quality in colleges and universities and from the perspective of teaching total quality management,this paper discussed on the way to construct the diversified,whole and comprehensive teaching quality management system in which both on-campus and off-campus interest parties can participate in and its potential effect on the ba-sis of an empirical study.
8.Digital orthopedics technology in preoperative planning of implant fixation for intertrochanteric fracture
Xin MIAO ; Gaorong DENG ; Qiang LING
Chinese Journal of Tissue Engineering Research 2016;20(13):1918-1924
BACKGROUND:Intertrochanteric fractures can be generaly treated by surgical treatment. Along with deep research on the biomechanics of the proximal femur, proximal femoral locking compression plate appears recently. The locking plate fixation is not strong, can reduce the local stress shielding, and maintain optimal system stability, but fracture fixation failure often occurs due to the inappropriate choice of nail plate. OBJECTIVE:To evaluate the value of digital orthopedics technology in preoperative planning in locking plate fixation for intertrochanteric fracture. METHODS: Forty intertrochanteric fracture patients receiving CT tomography femur upper segment were selected and divided into two groups. In the conventional group, after reading X-ray films and CT images, patients received locking plate fixation. In the computer planning group, before repair, fracture model was established using Mimics software to segment fracture fragments, simulate operation reset and 3-matic software was used to reconstruct locking plate and screws. Locking plate was assembled with Mimics to obtain the best plate position, best screw angle and screw length. Proximal femoral locking compression plate fixation was performed. Fluoroscopy times, operation time, blood loss and fracture healing time were compared in both groups. RESULTS AND CONCLUSION: Three-dimensional models of proximal femur were reconstructed, and a series of data were obtained. The optimal position of each plate was obtained from each patient. The screw length was predicted, so preoperative operation planning was realized. Al patients were folowed up for 6-20 months. Fluoroscopy times, operation time, and blood loss were significantly less in the computer planning group than in the conventional group (P < 0.05). No significant difference in fracture healing time was detected between the two groups (P > 0.05). These findings suggest that digital orthopedics technology used in intertrochanteric fracture can simulate the locking plate position, determine the screw placement angle and length of the screw in advance, and reduce fluoroscopy times, operation time, blood loss and screw position misalignment.
9.Orthogonal Study on Different Acupuncture Factors Based on Hypothalamic-pituitary-adrenal Axis in Rats with Kidney Yang Deficiency
Youjiang MIN ; Ling DENG ; Ensi HONG
Shanghai Journal of Acupuncture and Moxibustion 2016;35(3):339-343
Objective To observe the effect of acupuncture on the expressions of serum corticotropin-releasing hormone (CRH), pituitary adrenocorticotropic hormone (ACTH) and its mRNA, to discuss the predominant and secondary factors that influence the efficacy of acupuncture, and to explore the optimal combination of acupuncture parameters.Method The rat model of kidney yang deficiency was made by muscular injection with hydrocortisone. Serum CRH, pituitary ACTH and its mRNA expressions were taken as the observation indexes, and 4 influential factors (i.e. selection of acupoints, angle of needle twisting, frequency of needle twisting, and time of needle twisting) plus 3 levels of each factor were arranged to L9(34) orthogonal table. A computer-controlled acupuncture manipulation device was used to treat the kidney yang rats. Serum CRH and pituitary ACTH were detected by enzyme-linked immunosorbent assay (ELISA) and pituitary ACTH mRNA expression by real time fluorescent quantitative PCR, to illustrate the primary and secondary factors that affect the acupuncture effectiveness.Results Regarding the effect on acupuncture effectiveness, the time of needle twisting ranked the top, followed by frequency of needle twisting, angle of needle twisting, and selection of acupoints. Angle of needle twisting, frequency of needle twisting, and time of needle twisting should be the predominant factors or secondary factors in influencing acupuncture effectiveness (P<0.01 orP>0.05). Selection of acupoints should be an important factor or secondary factor in influencing acupuncture effectiveness (P<0.05 orP>0.05).Conclusion For rats with kidney yang deficiency, the optimal acupuncture parameters combination should be acupuncture at Shenshu (BL 23), with twisting angle by 90°, twisting frequency at 180/min, and needle twisting time 120 s. Different factors can produce different effects on the therapeutic efficacy of acupuncture in treating rats with kidney yang deficiency; among the factors, the time of needle twisting produces the most significant effect, followed by frequency of needle twisting, angle of needle twisting, and selection of acupoints.
10.Hepatitis B virus antigen expression and Helicobacter pylori infection in gastric mucosa of patients with chronic liver disease
Nailing CHEN ; Ling BAI ; Tao DENG
Chinese Journal of Digestive Endoscopy 1996;0(05):-
0.05). Conclusions (l)There are obvious expression of HBV antigen in the gastric mucosa of patients with chronic liver disease and cirrhosis . Its role in the pathogenesis of gastric mucosal lesion is the worthful subject to be further studied. (2) No relationship between HBV antigen and Hp antigen expression was observed in this study.