Objective To explore new therapy method to reduce relapse of genital herpes(GH) with laser.Methods 550 cases GH treated with Laser were randomly derided into 11 different groups(each group 50 cases: group A(A.T.GH.Q),B(B.TGH.Q),C(C.T.GH.Q),D(D.TGH.Q),E(E.T.GH.Q),F(F.TGH.Q),G(G.T.GH.Q),H(H.T.GH.Q),I(I.T.GH.Q),J(J.T.GH.Q) and K group(K.T.GH.Q).All of cases started with 2~8 years of follow-up after clinical short-term being cured.Results Cure rate were: A 24%,B 22%,C 32%,D 30%,E 36%,F 448%,G 42%,H 48%,I 60%,J 58%,K 18%.Conclusion GH treated by Laser auompanied by drug has good and ideal long-term effectiveness,worthwhile for further study and popularized clinical application.

Objective The a seek in ideal of iatrotechnique is treatment of Traumatic Cerebral Tinnitus(TCT).Methods Use the pioneering of Laser Meridian Points Therapy(LMPT).The domestic He-Ne laser therapeutic instrument was used with optical fiber wave length 632.8nm,output power 2~30mW,therapeutic power quartz optical fiber at the end of fiber power 1~10 mW,diameter of optical patch at the end of the optical fiber 0.2cm,optical patch area 0.0314 cm2,power density 31.85~318.47mW/cm2.Use the optical fiber end of the instrument to contact and irradiated the following points:Yifeng(SJ 17),Yiming(Extra),Fengch'ih(GB 20),Yingyou,T'ingkung(SI 19),T'inghui(GB 2),Erhmen(SJ 21),Paihui(Du 20),et al.Each point each time was irradiated for 5~15 minutes of laser dosage(energy density)9.555~286.623J/cm2,once a day,7~14 days a course of treatment.Results 262 cases(503 ears)TCT(patients)of 215 cases(82.06%)414 ears(82.31%)showed tinnitus disapperance,45 case(17.18%)86 ears(17.10%)showed marked or some therapeutic effectiveness,2 case(0.76%)3 ears(0.59%)was ineffective.Follow-up survey 1~9 years of 157 cases 284 ears,found 141 case(89.81%)255 ears(89.78%)had their tinnitus disappeared,15 case(9.55%)27 ears(9.51%)showed marked effectiveness or some effectiveness,1 cases(0.64%)2 ears(0.70%)was ineffective.Conclusions LMPT for the treatment of TCT is the pioneering technique we have developed.Better than any other therapies at present and having good short-term effectiveness and stable and ideal long-term effectiveness.LMPT is worthwhile for further study and popularized clinical application.

Objective To seek an ideal treatment for tinnitus.Methods Use the pioneering of Laser Meridian Points Therapy(LMPT).The domestic He-Ne laser therapeutic instrument was used with optical fiber wave length 632.8nm,output power 2～30mW,therapeutic power quartz optical fiber at the end of fiber power 1～10mW,diameter of optical patch at the end of the optical fiber 0.2cm,optical patch area 0.0314cm～2,power density 31.85～318.47mW/cm～2.Use the optical fiber end of the instrument to contact and irradiate the following points:Yifeng(SJ 17),Yiming(Extra),Fengch'ih(GB20),Yingyou,T'ingKung(SI 19),T'inghui(GB 2),Erhmen(SJ 21),Paihui(Du 20),et al.Each point each time was irradiated for 5～15 minutes of laser dosage(energy density)9.555～286.623J/cm～2,once a day,7～14 days a course of treatment.Results 1808 cases(3037 ears)tinnitus(patients)of 1469(81.25%)cases 2686(81.22%)ears showed disapperance,313(17.31%)cases 577(17.45%)ears showed marked or some therapeutic effectiveness,26(1.44%)cases 44(1.33%)ears was ineffective.Follow-up survey 1～9 years of 1139 case 2043 ears found 936(82.18%)cases 1678(82.14%)ears had their tinnitus disappeared,188(16.51%)cases 340(16.64%)ears showed marked effectiveness or some effectiveness,15(1.32%)cases 25(1.22%)ears was ineffective.Conclusions LMPT for the treatment of tinnitus is the pioneering technique we have developed.Better than any other therapies at present and having good short-term effectiveness and stable and ideal long-term effectiveness,LMPT is worthwhile for further study and popularized clinical application.

Objective To analyze the associations of the interleukin-10 (IL-10) promoter-1082G/A and-819C/T single nucleotide polymorphism (SNP) and serum level of IL-10 with intracranial aneurysm (IAs). Methods The polymerase chain reaction (PCR) and DNA direct sequencing methods were used to detect IL-10 gene promoter district two SNP site,-1082G/A and-819C/T genotype frequency and allele frequency in 206 patients with IAs and 187 controls. Chi-square test was used to analyze differences between two groups. The serum level of IL-10 was analyzed by ELISA, and t-test was used to analyze significant differences between two groups. Results There were significant differences in genotypes of GG and GA+AA, as well as the alleles G and A, in-1082G/A locus between IAs group and control group (P<0.01). There were higher frequencies of genotype GA+AA and the allele A in IAs group than those in control group (P<0.01). There was higher risk of suffering IAs in patients with genotype GA+AA (OR=4.137, 95%CI:2.476-6.914) and the allele A (OR=3.368, 95%CI:2.476-4.583). There were higher frequencies of the genotype CT+TT and the allele T in-819C/T locus in IAs group than those of control group (P<0.01). There was higher risk of suffering IAs in patients with genotype CT+TT (OR=3.393, 95%CI:1.952-5.900) and the allele T (OR=3.764, 95%CI:2.730-5.192). The serum level of IL-10 was significantly lower in IAs group than that of control group (P<0.01). Conclusion The IL-10 promoter SNP influences the expression of IL-10. IL-10 promoter-1082G/A and-819C/T polymorphisms are correlated with the formation of IAs.

Objective To explore body image(BI),prosthesis satisfaction and quality of life(QOL)of amputees from Wenchuan earthquake and the relationship among them to provide evidence for the intervention.Methods A total of 21 amputees accepted a survey regarding QOL,BI,and satisfaction with prosthesis.The scale of SF-36 was used to assess QOL.Amputees Bodily Image Scale(ABIS)was;used to assess BI.A self-design questionnaire wag used to evaluate the prosthesis satisfaction of amputees.Results The scores of SF-36,ABIS,and prosthesis satisfaction wag 41.90 ±15.00,64.58 ±10.60,and 59.52±11.06,respectively.The ABIS scores in women(65.07 ±12.10)were hisher than that in men(63.20 ±5.0)(P＜0.05).There was a positive correlation between score of QOL and prosthesis satisfaction,but a negative correlation between QOL and BI.The negative correlations were also observed between BI and Vitality,BI and mental health.Prosthesis satisfaction had positive correla tions with education level.QOL and mental health.Conclusion The body image disturbance(BID)and dissatis faction with prosthesis may cause negative influences on the amputees'quality of life.Relevant intervention should be provided of amputees handling their prostheses and body images correctly and raising QOL.

OBJECTIVE: To investigate the perioperative electrolyte imbalance in patients undergoing gastrointestinal surgery. METHODS: Retrospective case analysis was used in this study. Patients who underwent gastrointestinal surgery under general anesthesia at the Sixth Affiliated Hospital of Sun Yat-sen University from January to April 2018 were selected through electronic medical records system. Blood gas analysis during surgery must be carried out in the enrolled patients. Patients with excessive fluid infusion, critical conditions or patients who had been enrolled in other clinical trials were excluded. A total of 999 patients were enrolled. The preoperative, intraoperative and postoperative concentrations of serum sodium, potassium and calcium were collected by the last biochemical examination before surgery, arterial blood gas analysis within 1 h after anesthesia and another biochemical examination within 24 hours after surgery respectively. The type and incidence of electrolyte imbalance were then analyzed, and logistic regression analysis was used to investigate the risk factors. RESULTS: In the 999 patients, 683 cases were male (63.9%) and 361 cases were female(36.1%), with an average age of (56.9±14.6) years old. Fifty-eight patients (5.8%) underwent emergency surgery and 941 patients (94.2%) underwent elective surgery; Sixty-two patients were treated with laxatives at least 3 times and 115 patients were treated with enema at least 3 times before operation. The incidence of hypokalemia was 49.6%(496/999) intraoperatively and decreased to 15.2%(152/999) postoperatively. No hyperkalemia cases were found. The incidence of hypocalcemia was 53.8%(537/999) intraoperatively and increased to 79.7% (796/999) postoperatively. The incidence of hypokalemia in ileus patients was 33.3%(17/51) before surgery, which was higher than that in patients with colorectal cancer [12.3%(86/703)], patients with gastric cancer [7.8%(8/104)] and patients with other gastrointestinal diseases[10.6%(15/141)] (all P<0.05). Similarly, the preoperative and intraoperative incidence of hyponatremia in ileus patients were both 15.7%(8/51), which were higher than those in patients with colorectal cancer [3.0% (21/703) and 2.3% (16/703)] and patients with gastric cancer [2.9%(3/104) and 1.9%(2/104)]. The incidence of hypocalcemia in ileus patients was 31.4%(16/51) preoperatively, which were also higher than those in patients with colorectal cancer [7.4%(52/703)] and patients with gastric cancer [8.7%(9/104)] (all P<0.05). Logistic regression analysis showed that ileus and emergency surgery were risk factors for patients with preoperative electrolyte imbalance; preoperative electrolyte imbalance was a risk factor for intraoperative electrolyte imbalance; intraoperative electrolyte imbalance was a risk factor for postoperative electrolyte imbalance; preoperative electrolyte imbalance was a risk factor for postoperative imbalance of sodium and potassium. CONCLUSIONS The incidence of electrolyte imbalance is high in patients undergoing gastrointestinal surgery, especially hypocalcemia and hypokalemia. It is necessary to recognize the electrolyte abnormality timely and give active intervention and correction.
Adult ; Aged ; Digestive System Surgical Procedures ; Electrolytes ; Female ; Humans ; Hyponatremia ; Ileus ; Male ; Middle Aged ; Postoperative Complications ; prevention & control ; Retrospective Studies ; Risk Factors ; Water-Electrolyte Imbalance