Background: Wound healing mechanisms still unclear. Wounds are physical injuries that result in an opening or breaking of the skin. Proper healing of wounds is essential for the restoration of disrupted anatomical continuity and disturbed functional status of the skin. This is a product of the integrated response of several cell types to injury. Wound healing is a complex process that results in the contraction and closure of the wound and restoration of a functional barrier.Goal: The purpose of this study was to determine burn wound healing activity of Calvacin. Materials and Methods:We used in study as colored reaction thin layer chromatography (TLC) and UV-spectrophotometer methods to determine active compounds in the three component drug "Calvacin".In research were inducted 20 healthy white mice and 40 rats. Investigation was based and implemented at scientific research laboratory of Traditional Medical Science Technology and Production Corporation and Institute of Veterinary medicine of pathological laboratory. The study protocol was approved by the Ethics Committee of the Ministry of Health.Results:Results of the phytochemical investigations showed that contained in the new drug "Calvacin" determined the presence of bioactive substances such as flavonoids, saponin, tannin, curcuminoids, organic acids and minerals. Substance was absorbed 25.7% in 40 grade ethanol, 27.1% in 70 grade, 22.2% in 96 grade and 19.6% in sterile water. We was established quality quantities of Calvacin in the drug amount summary flavonoids 1% and determined by UV spectrophotometer method. Proceeding from the absorption maximum of the substances analyzed the wave length of detection was determined as 370nm. In the result of mineral study of the "Calvacin", Ca^2.3%, P-6.17%, K-5.58%Burn wound healing time is control group 35±0.1 days, on 26±0.1 day animals of Calvacin group, but animals of Vishinski's ointment group 33±0.1 (p<0.05).Conclusions:1. The phytochemical investigations contained in the "Calvacin" drug determined the presence of bioactive substances such as flavonoids, saponin, tannin, curcuminoids, organic acids and minerals.2. Calvacin preparation has less toxic and significantly stimulate experimentally induced wound contract.

IntroductionNowadays the risk factors for thrombosis include blood stasis, vessel wall injury, and hypercoagulability, as proposed by Virchow over 150 years ago. We chose to study affect of Zomoshin 6 tan to the model of thrombosis formed in experimental animal. It was written in books and sudar that it has action of treating some type’s disease such as blood diluting, meeting frozen blood and treating some gynecological disease.PurposeTo study affect of Zomoshin-6 tan deep vein thrombosis model formed in experimental animal.Material and Methods30 male rats of wistar bread with 180-220 gram of weight for control group, experimental group or Zomoshin-6 tan and comparative group Warfarin. Thirty rats were equally divided into 3 groups: Group 1 received saline alone, Group 2 received Zomoshin-6 (200 mg/kg), and Group 3 received Warfarin as a positive control (0.25 mg/kg), seven days prior to the assessment of thrombus formation. Thrombus formation was also assessed histopathologically. Thrombi were detected in all rats after experimentallyinduced thrombosis.ResultsHistological analysis demonstrated the presence of thrombosis in the interior vena cava (IVC) of the control group, which contained fibrin, erythrocytes, and leucocytes and obstructed the lumen. Only a small amount of fibrin clot, containing a few leucocytes and large numbers of erythrocytes, were observed in the Zomoshin-6-treated group. The thrombus formed in the IVC of Warfarin-treated animals consisted of fibrin clot, which was mostly attached to the wall, with few leucocytes but abundant erythrocytes. These findings suggest that Zomoshin-6 is an effective antithrombotic agent.Conclusion:Zomoshin-6 tan has an action of inhibing thrombosis forming of vein in experimental animal.

BACKGROUND. The Mongolian traditional medicine Anar-5 is excellent for weak digestion and helps with stomach irritation, loss of appetite, and resulting body weakness. Anar-5 blends punicagranatum, cinnamomum cassia presl, piper longum, cardamom and alpiniaofficinarum. We are establish an experimental animal of chronic gastritis to investigate the effect of traditional medicine Anar-5 on rats gastric mucosa. Methods: In this study, the protective effect preparation in sixty five healthy, male wistar rats were treated with intragastric administration of ammonia water 0.1%. To rats in three experiments for 2 week, 4 week, and 6wk, gastric tissues were examined histopathologically for atrophic changes and blood’s gastrin produced by preparation treatment. Results: After the treatment of animals blood’s gastrin was significantly different from that in control group (p<0.05), and the gastric mucosal inflammation was infiltration of inflammatory cells, decreased thickness of lamina propria. Conclusion: Treatment with preparation from Anar-5 protectived by the chronic gastritis and gastric atrophy.