Objective To research the current stress status and job stressors of the nurses,and explore the measures of relieving stress.Methods Investigation was carried out in 199 nurses of Qilu hospital by using interviewing and surveying method basing on the literature research.Results 74.4% nurses work under high even very high stress.Benefit,promotion,workload and time allocation were the first three stressors.Ages,professional titles,education degree,departments were influential factors of stress.49.7% of the nurses were under high job burnout.Conclusions The nurses are under high work stress and job burnout.There should be measures from environmental level,organizational level,individual level to relieve and manage the stress.