Objective:To explore and study the clinical values of CT and MRI in the diagnosis of spinal trauma. Methods: One hundred patients with spinal trauma in our hospital were selected as the study objects and randomly divided them into 2 groups, 50 cases in each group. The control group was diagnosed by CT, the experimental group was diagnosed by MRI. Results: The efficacy of CT(control group) on fracture line and fracture flat shift was better than experimental group, but in the aspect of spinal cord injury, ligamentous injury and soft tissue injury, experimental group(MRI) was more sensitive than control group(x2=4.0, P<0.05), differences between 2 groups were statistically significant. Conclusion:Every coin has 2 sides, so as to applying CT and MRI in the diagnosis of spinal trauma, but the accuracy to overall spinal trauma of experimental group is higher. Furthermore, it can avoid misdiagnosing with spinal trauma that applying combined CT and MRI, it is worthy of being widely recommended in clinic.

Objective To evaluate the relationship between field of view (FOV) and quality of CT images. Methods Scanning of the phantoms of spatial resolution and density resolution was performed with FOVs of 25 cm?25 cm, 35 cm?35 cm, and 42 cm?42 cm, respectively, and the spatial resolution and density resolution of CT images with different FOVs were measured. 20 patients underwent CT scanning using 25 cm?25 cm and 35 cm?35 cm FOVs, respectively. The images were evaluated by 3 qualified CT doctors by using a double-blind reading. Results As FOVs changed, the spatial resolution and density resolution were different. The best spatial resolution and density resolution were obtained on 25 cm?25 cm FOV images. The best spatial resolution could distinguish four 0.6 mm-diameter eyelets, and the best density resolution could distinguish five 2.5 mm-diameter eyelets. The CT images with 25 cm?25 cm FOV were obviously better than those with 35 cm?35 cm FOV (P

BACKGROUND:With the continuous development of nanotechnology, a growing number of nanotechnologies have been used in the field of biological medicine, providing a great deal of interest for the diagnosis and treatment of disease. OBJECTIVE:To review the research situation of nanobiomaterials and its application in biological medicine. METHODS: The articles about nanobiomaterials and nano bioceramic materials were retrieved from Chinese Journal Ful-text Database, PubMed and Wanfang database published during January 2000 to October 2014 by the first author using computer. Key words were “nano, bioceramics” in Chinese and English, respectively. RESULTS AND CONCLUSION: With the development of nanotechnology, some nanotechnologies have entered the stage of practical application. Application of nanotechnology plays a preventive effect to the occurrence and development of disease. Nano-ceramic significantly increases the strength, toughness and superplasticity of materials, overcomes many deficiencies of biological ceramics, and has been widely used in the field of orthopedics, such as artificial joints, artificial bones, bone filing material, bone replacement materials, artificial vertebrae and so on.

Ankylosing spondylitis (AS) combined with spinal fractures with thoracic and lumbar fracture as the most common type shows characteristics of unstable fracture, high incidence of nerve injury, high mortality and high disability rate. The diagnosis may be missed because it is mostly caused by low-energy injury, when spinal rigidity and osteoporosis have a great impact on the accuracy of imaging examination. At the same time, the treatment choices are controversial, with no relevant specifications. Non-operative treatments can easily lead to bone nonunion, pseudoarthrosis and delayed nerve injury, while surgeries may be failed due to internal fixation failure. At present, there are no evidence-based guidelines for the diagnosis and treatment of AS combined with thoracic and lumbar fracture. In this context, the Spinal Trauma Academic Group of Orthopedics Branch of Chinese Medical Doctor Association organized experts to formulate the Clinical guideline for the diagnosis and treatment of adult ankylosing spondylitis combined with thoracolumbar fracture ( version 2023) by following the principles of evidence-based medicine and systematically review related literatures. Ten recommendations on the diagnosis, imaging evaluation, classification and treatment of AS combined with thoracic and lumbar fracture were put forward, aiming to standardize the clinical diagnosis and treatment of such disorder.