1.A Case of Tubular Apocrine Adenoma.
Na Young KO ; Jun Ha PARK ; Hyo Hyen AHN ; Young Chul KYE ; Soo Nam KIM
Korean Journal of Dermatology 2005;43(8):1145-1147
Tubular apocrine adenoma is a well-circumscribed, intradermal benign tumor, with tubular structures showing apocrine differentiation. Histologically, the characteristic features are various-sized dilated tubules with intraluminary papillary projection and apocrine decapitation secretion. It usually presents as a solitary lesion and is sometimes associated with nevus sebaceous and/or syringocystadenoma papilliferum. We have in report a case of tubular apocrine adenoma with epidermal cysts which developed in the right inguinal area of a 37-year-old man.
Adenoma*
;
Adult
;
Decapitation
;
Epidermal Cyst
;
Humans
;
Nevus
2.Hidradenoma Papilliferum Occurring on the Nasal Skin.
Hyun Jae LEE ; Deborah LEE ; So Young JUNG ; Soon Kwon HONG ; Jong Keun SEO ; Ho Suck SUNG
Annals of Dermatology 2011;23(Suppl 2):S254-S257
Hidradenoma papilliferum is a rare benign neoplasm that usually occurs in the female anogenital area. We present a 43-year-old female with a non-anogenital (ectopic) hidradenoma papilliferum on her nose. The patient had had a skin-colored subcutaneous nodule on her nose for 7 years. The histopathological findings showed variously shaped cystic spaces in the tumor. And the lumina were surrounded by a single or double layer of cell which showed decapitation secretion. In the English dermatological literature, only one case of ectopic hidradenoma papilliferum arising in nasal skin has been reported. Hence we suggest hidradenoma papilliferum occurring on the nasal skin is a peculiar and interesting event.
Acrospiroma
;
Adult
;
Decapitation
;
Female
;
Humans
;
Nose
;
Skin
3.Atypical Syringocystadenoma Papilliferum with Adenomatous Hyperplasia.
Sang Min HWANG ; Eung Ho CHOI ; Won Soo LEE ; Sung Ku AHN
Korean Journal of Dermatology 1997;35(5):967-970
We report a case of syringocystadenoma papilliferum (SCAP) occurring in a 28 year-old male who had a 2cm X 1cm X0.7cm sized papillomatous and cauliflower-like tumor on the left inguinal area without any subjective symptoms. A Histopathological examination revealed cystic invaginations which contained a few well defined papillary projections and proliferation of ductal structures at the periphery. The papillae were covered by columnar epithelial cells on the luminal side with frequent, tufting and piling up, whereas the underlying cells were small cuboidal ones and contained a vascularized stroma and dense lymphoplasma cell infiltration. The majority of ductules contained amorphous eosinophilic material and some showed intraluminal papillation and decapitation secretion. Immunohistochemical studies with S-100 antigen, CEA, and EMA were performed. Studies of S-100 antigen and EMA were nonspecific. CEA was positive in the amorphous intraluminal materials and apical cells of the lumen. The histopathological and immunohistochemical studies revealed rather typical findings of SCAP.
Adult
;
Decapitation
;
Eosinophils
;
Epithelial Cells
;
Humans
;
Hyperplasia*
;
Male
;
Phenobarbital
4.A Case of Tubular Apocrine Adenoma.
Hyun Jeong LEE ; Kee Young ROH ; Seog Jun HA ; Seok Jin KANG ; Jin Wou KIM
Annals of Dermatology 1999;11(4):297-299
Tubular apocrine adenoma is a well-circumscribed intradermal benign tumor with tubular structures showing apocrine differentiation. Most of those cases occur on the scalp in middle aged women. Histologically, tubular structure with apparent apocrine decapitation secretion, cystic dilatation of tubule, and connection with epidermis are the characteristic features of tubular apocrine adenoma. We presented a case of tubular apocrine adenoma that had recurred after incomplete excision. It showed apocrine decapitation secretion histologically and both eccrine and apocrine differentiation on immunohistochemical study.
Adenoma*
;
Decapitation
;
Dilatation
;
Epidermis
;
Female
;
Humans
;
Middle Aged
;
Scalp
5.A Case of Nodular Hidradenoma with Apocrine Differentiation.
Ho Chung LEE ; Soon Wook KWON ; Moo Kyu SUH ; Jae Woo LIM ; Soon Baek KWON ; Yeon Jin KIM ; Tae Jung JANG ; Kuk Hyeong LEE
Korean Journal of Dermatology 2004;42(11):1508-1510
Nodular hidradenoma is a relatively infrequent benign tumor that shows differentiation from or toward the structure of the eccrine sweat gland. We report a case of nodular hidradenoma with apocrine differentiation in a 74-year old female who had an asymptomatic, 3.5x2.7x1.0cm-sized, smooth-surfaced, round, erythematous to bluish tumor mass with cystic grape-like nature on the right thigh for 3 years. Histological findings showed a well-circumscribed tumor composed of solid portions with fusiform basophilic cells and clear round cells, cystic spaces, tubular lumina, squamoid feature and decapitation secretion.
Acrospiroma*
;
Aged
;
Basophils
;
Decapitation
;
Female
;
Humans
;
Sweat Glands
;
Thigh
6.A Case of Apocrine Hidrocystoma of the Glans Penis.
Korean Journal of Dermatology 2000;38(4):563-565
Apocrine hidrocystoma is an uncommon benign tumor derived from the secretory segment of apocrine sweat glands and the cyst wall of this tumor consists of columnar to cuboidal cells with a decapitation secretion indicative of apocrine secretion. A 5-year-old boy had a translucent, flesh-colored cystic nodule, 5x2x2mm in size, on the glans penis near the urethral meatus for 4 years. Although apocrine hidrocystoma of the glans penis is very rare, characteristic histopathological features make it easy to diagnose as apocrine hidrocystoma of glans penis, which should be differentiated from the median raphe cyst of the penis.
Child, Preschool
;
Decapitation
;
Hidrocystoma*
;
Humans
;
Male
;
Penis*
;
Sweat Glands
7.Apocrine Mixed Tumor with Follicular Differentiation.
Hyun Jeong LEE ; Kee Young ROH ; Won Keun AHN ; Seog Jun HA ; Jin Wou KIM
Annals of Dermatology 2000;12(1):52-55
Mixed tumor of the skin (chondroid syringoma) is a rare benign tumor composed of epithelial elements intermingled with myxoid or cartilagenous stroma which is not separated by basement membrane. It had been believed to originate from the eccrine gland but recently, it was described to be of apocrine gland origin in case of showing apparent apocrine secretion. We report on a 63-year-old man with a tumor on the right upper eyelid showing typical microscopic features of mixed tumor of the skin. Many apocrine decapitation secretions were seen in tubular structures and follicular differentiations were also seen, which represents the common origin of folliculo-sebaceous-apocrine unit.
Adenoma, Pleomorphic
;
Apocrine Glands
;
Basement Membrane
;
Decapitation
;
Eccrine Glands
;
Eyelids
;
Humans
;
Middle Aged
;
Skin
8.Effect of Baclofen on the Cholinergic Nerve Stimulation in Isolated Rat Detrusor.
Kwang Youn LEE ; Keun Mi LEE ; Eun Mee CHOI ; Hyoung Chul CHOI ; Jeoung Hee HA ; Won Joon KIM
Yeungnam University Journal of Medicine 1995;12(2):246-259
This study aimed to investigate the mechanism of action of baclofen on the detrusor muscle isolated from rat. Rats (Sprague-Dawley) were sacrificed by decapitation and exsanguination. Horizontal muscle strips of 2 mm x 15mm were prepared for isometric myography in isolated muscle chamber bubbled with 95% / 5%-OZ / CO2 at 371C, and the pH was maintained at 7.4 Detrusor strips. contracted responding to the.. electrical field stimulation (EFS) by 2 Hz, 2U msec, monophasic square wave of 60 VDC. The initial peak of EFS-Induced contraction was tended to be suppresed by a,p-methylene-adenosine 5'-triphosphate (mATP), a partial agonist of purinergic receptor, and baclofen, a GABAB receptor agonist (statistically nonsignificant). The late sustained contraction by EFS was suppressed significantly (p < 0.05) by additions of atropione, a cholinergic muscarinic receptor antagonist and baclofen. The adenosine 5'-triphosphate-induced contraction was completely abolished by mA TP but not by baclofen. In the presence of atropine, the subsequent addition of acetylcholine could not contract the muscle strips: but the addition of acetylcholine in the presence of baclofen evoked a contraction to a remarkable extent.
Acetylcholine
;
Adenosine
;
Animals
;
Atropine
;
Baclofen*
;
Decapitation
;
Exsanguination
;
Hydrogen-Ion Concentration
;
Myography
;
Rats*
;
Receptors, Muscarinic
9.Multiple Eccrine Hidrocystoma Treatedwith 1% Topical Atropine Sulfate.
Tae Ho YANG ; Youn Soo KIM ; Mi Kyeong KIM ; Tae Young YOON
Annals of Dermatology 2001;13(4):262-264
We report a case of multiple eccrine hidrocystoma (MEH) in a 57-year-old woman who had asymptomatic, discrete, skin-colored, shiny, firm papulovesicles on the face. These lesions enlarged during summer or when the patient did housework, and decreased in sue during winter or rest. Histologic examination showed a dilated, unilocular, cystic, invaginated structure within the middle dermis. The wall of the cyst generally consisted of two layers of Rat or cuboida1 epithelial cells. Decapitation secretion and myoepithelial cells were not observed. The lesions improved markedly with 1% topical atropine sulfate.
Animals
;
Atropine*
;
Decapitation
;
Dermis
;
Epithelial Cells
;
Female
;
Hidrocystoma*
;
Housekeeping
;
Humans
;
Middle Aged
;
Rats
10.A case of apocrine sweat gland carcinoma in the scrotum.
Sang Kook YANG ; Jae Mann SONG ; Soon Hee JUNG
Korean Journal of Urology 1991;32(5):853-856
Apocrine sweat gland carcinoma is a very unusual malignant skin adnexal tumor and mostly occurs in areas where apocrine elands are abundant namely. axilla. upper arm. scalp. eyelid. vulva and external auditory meatus. The scrotal location is not yet reported. We report a case of apocrine sweat gland carcinoma of scrotum in a man aged 85, which was managed by local excision. The histologic finding is that of poorly differentiated adenocarcinoma. Evidence of decapitation secretion typical or apocrine glands. is present in some areas.
Adenocarcinoma
;
Apocrine Glands
;
Arm
;
Axilla
;
Decapitation
;
Eyelids
;
Scalp
;
Scrotum*
;
Skin
;
Sweat Glands*
;
Sweat*
;
Vulva