Monthly demographic surveillance by local reporters was continuous in the Tari Basin from 1971 until 1995 and cause of death was determined primarily by verbal autopsy. In 1982 the de jure population was 26,500, 15% aged less than 5 years. Crude birth rate was 34/1000/annum in 1980-1984; from 1977 to 1983 crude mortality rate was 15/1000/annum and life expectancy at birth 50 years. Infant mortality fell from 160 in the 1920s to 72/1000 livebirths in the 1970s, the greatest decline occurring between 1952 and 1971 when antibiotics became widely available. Respiratory disease (particularly chronic lung disease in adults) accounted for 39% of all deaths, and pneumonia for 50% and 33% of infant and toddler deaths respectively. Very few deaths from pigbel have occurred since the introduction of pigbel vaccine. Initially childhood mortality from diarrhoea declined following introduction of an oral rehydration program but subsequently rose when medical attention was no longer sought and children were inadequately treated at home. The higher mortality in the lower-lying Iumu area was attributed to malaria. Since the opening of the Highlands Highway in 1981, there has been a dramatic increase in short-term movement of both men and women in and out of Tari resulting in increased incidence of sexually transmitted diseases and viral infections such as measles. If restored, the Tari Research Unit could continue to play a key role in assisting the Department of Health in making decisions on appropriate interventions to improve the quality of life of Papua New Guineans.
Basin ; Aspects of mortality statistics ; seconds ; Infant ; etiology

Feeding and dietary regimes ; Respiratory ; morbidity aspects ; Acute ; Malaria

We have used nested polymerase chain reaction (PCR) and the PCR-based endonuclease digestion method to genotype Chlamydia trachomatis serovars in 460 infected individuals from the Eastern Highlands Province of Papua New Guinea. Our study groups comprised women who presented in labour to the Goroka Base Hospital, their newborn infants, symptomatic children who presented to the hospital's Outpatients Department and men and women from 15 randomly selected villages in the Asaro Valley. In this analysis, the major outer membrane protein (MOMP) gene, omp1, of C. trachomatis was amplified using DNA obtained from the endocervix of women, urine from men, and both the eye and nasopharynx of children. Amplified DNAs were digested concurrently using Alul and a combination of EcoRI, Hinl and Hpall restriction enzymes. The mixtures were separated on electrophoretic gels and the respective serovars designated on the basis of resolved digested DNA patterns. Our results, which were confirmed also by omp1 sequence data, show serovars D, E, F, G, H and L3 to be present in the studied communities. The overall relative frequencies of these serovars were 30%, 21%, 25%, 1%, 20% and 2% respectively, with serovars D, E, F and H accounting for 97% of these infections. Double infections among these principal serovars were also detected in all our study groups but at a low overall frequency of 3%. Serovar D was the major agent involved in the aetiology of chlamydial infection in both children and adults though serovar F was the most frequent in newborn infants. Serovar H was relatively less frequent in symptomatic children. No trachoma-related serovars were detected, confirming the rarity of this disease in Papua New Guinea. In contrast, although clinical cases of lymphogranuloma venereum have not been described in the country, the detection of serovar L3 in this study suggests that it may occur. However, the association of L3 also with childhood infection indicates that it may be causing the same pathology as the serovars D-K that are associated with non-ulcerative sexually transmitted infections.
Upper case dee ; Papua New Guinea ; Child ; upper case aitch ; Upper case eff