2.Sinonasal natural killer/T-cell lymphoma presenting as pyrexia of unknown origin with nasal symptoms.
Betsy K H SOON ; Xin-Rong LIM ; Deborah H L NG ; Ming-Yann LIM
Singapore medical journal 2014;55(7):e109-11
A 68-year-old Chinese man presented with an eight-month history of pyrexia of unknown origin and chronic sinusitis despite multiple courses of antibiotics. He underwent extensive investigations, including workups for infections, chronic granulomatous diseases and malignancy. Nasal biopsies were performed twice under local anaesthesia, but did not show any evidence of malignancy. Eventually, the patient was diagnosed with natural killer (NK)/T-cell lymphoma, nasal variant, based on histopathological findings from harvested deep tissue obtained via functional endoscopic sinus surgery. This study highlights that, for patients presenting with pyrexia of unknown origin and nasal symptoms, NK/T-cell lymphoma must be considered as a differential diagnosis. Generous amounts of tissue should be harvested under general anaesthesia rather than limited tissue under local anaesthesia, in order to facilitate and ensure a definitive diagnosis.
Aged
;
Anti-Bacterial Agents
;
chemistry
;
Biopsy
;
China
;
Humans
;
Lymphoma, Extranodal NK-T-Cell
;
diagnosis
;
diagnostic imaging
;
pathology
;
Male
;
Nasal Cavity
;
pathology
;
Nose Neoplasms
;
complications
;
diagnosis
;
radiotherapy
;
Prognosis
;
Radiography
;
Radiotherapy
;
Sinusitis
;
complications
;
diagnosis
;
Treatment Outcome
4.Opening our eyes to guide dogs for the blind in Singapore.
Deborah H L NG ; Rebecca Y K CHEW ; Francis SEOW-CHOEN ; Cheng Hock KUA ; Kah Guan Au EONG
Annals of the Academy of Medicine, Singapore 2008;37(9):806-808
Animals
;
Behavior, Animal
;
Blindness
;
rehabilitation
;
Bonding, Human-Pet
;
Culture
;
Dogs
;
Humans
;
Locomotion
;
Singapore