The standard non-surgery approach for locally advanced non-small cell lung cancer (NSCLC) is concurrent chemoradiotherapy.Common chemotherapy regimens include EP,NP,DC and PC.New chemotherapy drugs combination and targeted therapy are still under study.The tolerances of elderly patients are declining for concurrent chemoradiotherapy,but it is not the absolute contraindication.The tolerance for hyperfraction and high dose radiotherapy is well,however,the effectiveness and long-term toxicity need to be further studied and evaluated.

Comprehensive therapy is widely received for esophageal carcinoma in our country and worldwide. The treatment approaches consist of sugery,radiotherapy and chemotherapy,and chemoradiation therapy is very important. Many randomized controlled studies and meta-analysis reveal that preoperative neoad-juvant chemoradiotherapy and radical concurrent chemoradiation are the preferred modalities for local advanced esophageal carcinoma.