1.Research on the Effect of Electro-acupuncture of Neiguan on the CGRP Content in Migraine Rats' Plasma
Journal of Zhejiang Chinese Medical University 2007;0(01):-
[Objective] To study the effect of eletro-acupuncture of Neiguan on the CGRP in rats' plasma and its functional mechanism.[Method] Inject subcutaneously GTN to make rats migraine model.After electro-acupuncturing Neiguan,take radio-immune method to measure the CGRP content in rats' plasma of experimental group.[Result] Electro-acupuncturing Neiguan can reduce rats CGRP content.[Conclusion] To inject subcutaneously GTN can raise rats' plasma CGRP content,electro-acupuncturing Neiguan can reduce risen CGRP,regulate vascular extension,improve nerve inflammation,thus relieve migraine symptoms.
2.THE ANTAGONISTIC ACTIVITIES OF BOTH BACILLUS CEREUS 357 AND ITS ANTAGONISTIC SUBSTANCE AGAINST BOTYTIS CINEREA PERS. AND RHIZOCTONIA SOLANI
Xiaoxi CHEN ; Weiliang CHEN ; Debao LI ;
Microbiology 1992;0(04):-
Bacillus cereus 357 and its antagonistic substance can effectively ant agonize Botytis cinerea Pers and Rhizoctonia solani They can inhibit or kill t he hyphae of Rhizoctonia solani and Botytis cinerea Pers In addition, they can inhibit the growth of hyphae?the formation as well as the germination of spore of Botytis cinerea Pers The antagonistic substance is stable against heat ?acid and alkali and enzyme
3.Significance of dynamic detection of free DNA in hypertensive cerebral hemorrhage
Jiafeng NIU ; Lei JIA ; Xue LI ; Zongxiang LI ; Qing LI ; Debao ZHOU
International Journal of Laboratory Medicine 2014;(20):2779-2780,2783
Objective To study the relationship between the dynamic change of free DNA in cerebrospinal fluid (CSF)and the tissue injury in the patients with hypertensive intracerebral hemorrhage.Methods 54 cases of hypertensive intracerebral hemor-rhage were divided into 3 groups according to the glasgow coma scale(including 17 mild cases,21 moderate cases and 16 severe ca-ses).2 mL of CSF was collected for extracting free DNA on 1,3,7,15 d after stroke onset.The free DNA level was measured by the fluorescent real-time PCR.Results The free DNA level in the severe group was significantly higher than that in the mild and mod-erate groups.The free DNA level in the abnormal intracranial pressure group was higher than that in the normal intracranial pres-sure group;the intracranial infection group was higher than the non-infection group.Conclusion The free DNA level has certain value for diagnosing the craniocerebral injury in hypertensive intracerebral hemorrhage and is conducive to monitor the occurrence of postoperative complications.
4.Evaluation on drill method to prepare for healthcare-associated infection outbreak
Chunmei TIAN ; Ziyuan LONG ; Lanjun GUO ; Debao LI ; Ying ZHENG ; Xiaoxia GUO
Chinese Journal of Infection Control 2015;(3):199-201
Objective To evaluate the drill method to prepare for healthcare-associated infection (HAI)outbreak, and strengthen the control of HAI outbreak.Methods According to two cases of surgical site infection (SSI)re-ported by a neurosurgical department on January 16,2014,HAI outbreak emergency drill was started,SSI occurred from January 2012 to January 2014 were analyzed,specimens of air,object surface and hands of health care workers (HCWs)in the SSI-related operating room and neurosurgical intensive care unit(NSICU)were taken and analyzed. Results In July 2013,3 cases of SSI occurred in neurosurgical department (1 case was suspected of SSI,and didn’t per-form cerebrospinal fluid culture),SSI didn’t exceed 2 cases in the other months,and SSI outbreak couldn’t be confirmed. 16 specimens of air,object surface and hands of HCWs in operating room were taken,microbial detection results were all qualified.13 specimens of air,object surface and hands of HCWs in NSICU were taken,qualified rate was 61.54%;and mould was detected from 2 air specimens.24 disposable objects of neurosurgical department were performed bacterial cul-ture,3 were positive,and all were qualified after repeated detection.Conclusion HAI outbreak drill is helpful for HAI management professional personnel to grasp the method of HAI outbreak investigation method,improve the correct hand washing of surgeons and nurses,strengthen the standard operating procedure,and ensure the safety of pa-tients.
5.Research on the experimental progress of traditional Chinese medicine treating gouty arthritis
Wei YAN ; Yan LI ; Hongjiang JIANG ; Debao ZOU ; Lei LI ; Xin YU
International Journal of Traditional Chinese Medicine 2020;42(4):398-402
This article reviewed and summarized the experimental researches on the treatment of gouty arthritis (GA) with traditional Chinese medicine in recent years, which showed that the traditional or modified animal models of disease were widely used, and also concerned about the the model of integrating the disease and symptoms. However, few are about the application of combined disease and syndromes model. The mechanism research result shows that, single Chinese herb, component extract of Chinese herbs and Chinese herbal compound all play an important role in inhibiting inflammation, regulating signal pathway, anti-oxidation, reducing uric acid, increasing feeling of pain and regulating body metabolism.
6. One patient with chronic refractory wound caused by bamboo sticks in lower leg
Debao LI ; Zhijia ZHANG ; Hengjin TIAN
Chinese Journal of Burns 2018;34(10):727-728
One patient with chronic refractory wound in right lower leg was admitted to our department in June 2017, which experienced repeated ulceration for 4 years. On 4 days post admission, two bamboo sticks were taken out from the deep muscle of the right lower leg. The wound was repaired by perforator flap of posterior tibial artery in the right lower leg. The donor site was covered with split-thickness skin in the upper leg of the same side. On 7 days post operation, the flap and skin graft survived. During follow-up of 12 months, the flap had good appearance. This case suggests that the first thing for the treatment of chronic refractory wound is to find out the cause of wound.
7. Associations of parental thalassemia with preterm birth and low birth weight
Xiaochun HUANG ; Xiaoqiang QIU ; Xiaoyun ZENG ; Shun LIU ; Fanglian WEI ; Yanning LI ; Tao LIU ; Yanan WU ; Baoying FENG ; Qunjiao JIANG ; Dongping HUANG
Chinese Journal of Epidemiology 2019;40(5):596-600
Objective:
To investigate the association between the preterm birth and low birth weight and parental thalassemia.
Methods:
Pregnant women and their husbands receiving prenatal examination in local hospitals or maternal and child health centers in Jingxi and Debao in Guangxi from January to December 2017 were selected as study subjects. A total of 758 pregnant women with pregnancy outcomes and their husbands, who were both or alone diagnosed with thalassemia through thalassemia gene detection, were selected as case group and 758 pregnant women with pregnancy outcomes and their husbands, who were negative in thalassemia gene detection and hemoglobin electrophoresis test were selected as control groups. The case group were further divided into mother group, father group and both mother and farther group. Clinical and pregnancy outcome data of the study subjects were collected for the analysis on the association between parental thalassaemia and preterm birth or low birth weight by the independent sample
8.Hemodynamic Study on Non-Newtonian Properties of Fontan Procedure
Jiwen XIONG ; Weiru LUO ; Debao LI ; Qi SUN ; Jinlong LIU
Journal of Medical Biomechanics 2021;36(6):E862-E868
Objective To investigate the effects of non-Newtonian properties on hemodynamic characteristics of Fontan procedure in computational simulation. Methods A Fontan vascular model was reconstructed based on patient-specific medical images. The boundary conditions were set according to velocity profiles measured by real-time echocardiography. The Newtonian model and two non-Newtonian (Casson and Carreau) models were applied to analyze the hemodynamic parameters, including flow ratio (FR), energy loss (EL), wall shear stress (WSS) as well as non-Newtonian importance factor, so as to compare flow differences between the Newtonian model and non-Newtonian models. Results The rheological models had small effects on the FR. The EL of non-Newtonian models was higher than that of the Newtonian model, and the EL of Casson model was the highest. Flow recirculation and flow disturbance accompanied with low WSS were observed in inferior vena cava (IVC). At low inflow velocity, flow disturbance in IVC of Newtonian model was more obvious. The calculations of non-Newtonian importance factor suggested significant non-Newtonian viscosity in IVC. Conclusions Non-Newtonian viscosity is significant in IVC where low velocity and flow recirculation are observed. Non-Newtonian properties of the blood should be considered in patient-specific hemodynamic simulation of Fontan procedure.