OBJECTIVE:To investigate the pharmacotherapy for Parkinson disease(PD)and the factors influencing the choice of the treatment schemes for the PD patients.METHDOS:A total 269 patients with PD were assigned to 3 groups:Group I(Dopamine Agonist or Antan),Group Ⅱ(L-dopa),and Group Ⅲ(L-dopa plus Dopamine Agonist).The possible relative factors such as patients' age and sex,pathogenetic condition,educational level,occupation and income etc were analyzed statistically.RESULTS:The P value of the likelihood ratio test concerning the investigated factors such as age,sex,pathogenetic condition,education level,occupation and income were all less than 0.05 among patients treated with different kinds of therapy.The logistic regression analysis showed that all the six factors mentioned above had influence on the choice of therapy.CONCLUSION:The PD patient's selection of therapy was affected by his age and sex,pathogenetic condition,education level,occupation and income.

In the present study an experimental animal model of closed chest cardiac contusion in dogs was successfully established by impacting precardial area at the velocity of 9- 1 - 10. 5m/s with home-made elastic cord propelled impactor, After impact, some significant abnormalities of the left and right ventricular pressure,ECG and heart rate were recorded. Cardiac contusions were demonstrated at au-topsy. The establishment of the experimental cardiac contusion model could provide the tool for further study on nonpenetrating cardiac injury.

OBJECTIVE: To establish the quality standard of Buqi tongmai capsule.METHODS:Salviae miltiorrhiza,Ligusticum chuanxiong,Borneolum Syntheticum,Citrus aurantium were identified qualitatively by TLC.The content of astragaloside A was analyzed quantitatively by TLC scanning method.RESULTS: The specificity of S.miltiorrhiza,L.chuanxiong,Borneolum Syntheticum and C.aurantium could be analyzed qualitatively by TLC.The linear range of astragaloside A were 0.274 2～4.934 7 ?g (r=0.998 9) with an average recovery of 96.56%(RSD=2.70%,n=5).CONCLUSION: Established quality standard can be used for the quality control of Buqi tongmai casuple.

0.05).The metastasis rate in patients with both C-erbB-2(+) and MDR1(+) was higher than the others.Their prognosis was negative.The metastasis rate in patients with both C-erbB-2(+) and Nm23(-) was higher than the others.Conclusion There are correlation between C-erbB-2,Nm23,MDR1 expressions and metastasis of breast cancer.Multi-predictors are better guide to patients than single predictor.

WANG Qing-ren's opinion of "brain governs spirit" is different from the traditional opinion of "heart governs spirit" in Chinese medicine. Analysis on his theoretic foundation and demonstration process in ‘Correction on Errors in Medical Classics’ shows that his opinion on spirit is the logical conclusion of denying "heart storing spirit" and an organic part of his idea of human body;On the other hand,it reflects the partial insistence and superficial understanding of visible evidence. WANG Qingren's opinion of "brain governs spirit" shall not be isolated from his medicine theory,but an epitome of it.

Team building and teamwork mode have become the important parts in scientific research and clinical approach of critical care medicine (CCM). Team is a group composed of several individuals with different abilities, complementary roles and mutual dependence based on the common goal. Teamwork mode refers to that each member of the team, as a part of the community, completes the common goal through synergy based on the common knowledge system, according to the unified way of thinking. With the characteristics of CCM and the improvement of knowledge system and thinking system, the team building and teamwork mode of CCM has experienced a chaotic period, a molding period, an excitation period and a mature period. The team building and teamwork mode provide a strong internal impetus for the development of CCM.

In modern society,it is very important to prevent and control abrupt public health incidents.But the current education programs lack the relevant contents.Some tendencies exist:stressing disease prevention but lacking injury prevention;stressing techniques in hospital but lacking skills on scene;stressing test method but lacking information technology;stressing ordinary prevention but lacking measures in unexpected situations;stressing ability of techniques but lacking ability of organization,etc.We should integrate the pertinent knowledge of abrupt public health incidents into training programs for students of public health.

Objective To study the treatment influences on immunity and tumor recurrence of oral canc -er patients with the combination therapy of hyperbaric oxygen treatment and postoperative adjuvant chemotherapy . Methods In the period from March 2011 to March 2014 ,84 patients were clearly diagnosed with oral cancer and randomly divided into hyperbaric oxygen treatment combined postoperative adjuvant chemotherapy group ( group A,n=42)and postoperative adjuvant chemotherapy group (group B,n=42).From day 1 prior to the last day of chemotherapy ,patients in group A were treated with hyperbaric oxygen ,and patients in group B were just accepted chemotherapy.After chemotherapy,we tested the levels of CD3 +,CD4 +,CD8 +and NK cells by flow cytometry, and the expression of IL -2,IL-4,IL-10 and INF-γby ELISA essay.All patients had been followed for two years.Results The levels of CD4 +and NK cells in group A were higher than group B (P<0.05),but the levels of CD3 +and CD8 +between the two groups were obviously different (P>0.05).Compared with group B,the ratio of CD4 +and CD8 +was increased in group A(P<0.05).The levels of cytokines involved IL -2,IL-4,IL-10 and INF-γin group A were higher than the levels of group B ( P<0 .05 ) .Follow-up results showed that pa-tients treated with hyperbaric oxygen combined postoperative adjuvant chemotherapy had less recurrence in 2 years(P<0.05).Conclusion Hyperbaric oxygen combined postoperative adjuvant chemotherapy can improve the patients′immune function ,and to be effective in preventing two years′recurrence .

Objective:To explore the application value of multislice spiral CT scanning on abdomen for the detection of complication of acute pancreatitis.Methods: 120 patients with acute pancreatitis were divided into observation group (70 cases) and control group (50 cases) according to different detection method. The patients of control group were applied basic clinical detections included X-ray radiography and ultrasound imaging, while patients of observation group were supplemented CT detection besides these detections of control group. And situation of complication of patients in two groups were observed.Results: The positive rate of complications, which involved pancreatic pseudocyst, cellulitis, complications of gastrointestinal tract, pancreas hemorrhage and pancreatic ascites, in observation group was 97.14%, that was significant higher than that (62.0%) of control group (x2=24.74,P<0.05). Among 20 patients with pancreatic pseudocysts, there were 9 patients located at tails of pancreases, 6 patients located in bodies of pancreases, 3 patients located in small omental bursas, 2 patients located at heads of pancreases, and the CT images of them showed quasi-circular liquid form density lesions with clear boundaries appeared in lesion field. The CT images of cellulitis showed the volume of pancreas increased and the boundaries were fuzzy, and a larger range of density lesions with irregular soft tissue shape appeared in its periphery. CT detetions of gastrointestinal complications showed fuzzy point-shaped, strip-shaped and flake-shaped soft tissue-styled density shadow appeared in gastrointestinal tracts. The CT image of pancreatic ascites showed intraperitoneal fluid density shadow.Conclusion: Abdominal CT scan applied on patients with acute pancreatitis can increase the positive rate of complications and may be used as preferred detection method for clinical evaluation on the complications of acute pancreatitis.

Objective: Strengthen the school education of full-time medical junior college students,and to explore the teaching method of them. Methods:The teachers should adjust the teaching method in view of the teaching difficult points of full-time medical junior college students, to teach students in accordance with their aptitude:1)To go into the inner world of students, in-depth understand the characteristics of students;2)Enrich the teaching method and stimulate students' interest in learning; 3)To use the PBL teaching method properly; 4)To change the traditional examination methods;5)To strengthen the training of Teachers. Results:Self-confidence of the medical college students is strengthened, learning interest is improved, and learning effect is improved obviously through the teaching methods above. Conclusion:It can provide a good reference for teaching of medical junior college students through the methods of strengthen the school education of medical junior college students, and cultivate more qualified excellent medical talents for basic medical and health institutions.