Endometrial carcinoma can develop in patients less than 40 years old especially in the presence of chronic anovulation and infertility due to polycystic ovarian syndrome. Standard treatment involves staging laparotomy, including hysterectomy. However, this option may not be acceptable to a young patient who is still desirous of having children. Several trial of hormonal treatment as a means of conservative treatment in select patients has shown very good success rates. This is a case report of a twenty-five year old nulligravid with well-differentiated endometrioid adenocarcinoma of the endometrium who presented with anovulatory bleeding. Megestrol acetate was gicen at 160mg daily dose for three months. Sampling of the endometrium after the treatment showed regression of the carcinoma. Ovulation induction with clopmiphene citrate was done. Pregnancy was achieved seven months after carcinoma regression.
Human ; Female ; Adult ; ADENOCARCINOMA ; ENDOMETRIAL NEOPLASMS