1.Needle tract seeding following percutaneous biopsy of renal cell carcinoma.
Dwayne T S CHANG ; Hariom SUR ; Mikhail LOZINSKIY ; David M A WALLACE
Korean Journal of Urology 2015;56(9):666-669
A 66-year-old man underwent computed tomography-guided needle biopsy of a suspicious renal mass. Two months later he underwent partial nephrectomy. Histology revealed a 30-mm clear cell renal cell carcinoma, up to Fuhrman grade 3. An area of the capsule was interrupted, which corresponded to a hemorrhagic area on the cortical surface. Under microscopy, this area showed a tongue of tumor tissue protruding through the renal capsule. A tumor deposit was found in the perinephric fat. These features suggest that tumor seeding may have occurred during the needle biopsy.
Adipose Tissue/*pathology
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Aged
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Biopsy, Needle/*adverse effects
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Carcinoma, Renal Cell/*secondary/surgery
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Humans
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Image-Guided Biopsy/adverse effects
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Kidney/*pathology
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Kidney Neoplasms/*pathology/surgery
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Male
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*Neoplasm Seeding
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Soft Tissue Neoplasms/*secondary
2.Predictors of Esophageal Stricture Formation Post Endoscopic Mucosal Resection.
Bashar QUMSEYA ; Abraham M PANOSSIAN ; Cynthia RIZK ; David CANGEMI ; Christianne WOLFSEN ; Massimo RAIMONDO ; Timothy WOODWARD ; Michael B WALLACE ; Herbert WOLFSEN
Clinical Endoscopy 2014;47(2):155-161
BACKGROUND/AIMS: Stricture formation is a common complication after endoscopic mucosal resection. Predictors of stricture formation have not been well studied. METHODS: We conducted a retrospective, observational, descriptive study by using a prospective endoscopic mucosal resection database in a tertiary referral center. For each patient, we extracted the age, sex, lesion size, use of ablative therapy, and detection of esophageal strictures. The primary outcome was the presence of esophageal stricture at follow-up. Multivariate logistic regression was used to analyze the association between the primary outcome and predictors. RESULTS: Of 136 patients, 27% (n=37) had esophageal strictures. Thirty-two percent (n=44) needed endoscopic dilation to relieve dysphagia (median, 2; range, 1 to 8). Multivariate logistic regression analysis showed that the size of the lesion excised is associated with increased odds of having a stricture (odds ratio, 1.6; 95% confidence interval, 1.1 to 2.3; p=0.01), when controlling for age, sex, and ablative modalities. Similarly, the number of lesions removed in the index procedure was associated with increased odds of developing a stricture (odds ratio, 2.3; 95% confidence interval, 1.3 to 4.2; p=0.007). CONCLUSIONS: Stricture formation after esophageal endoscopic mucosal resection is common. Risk factors for stricture formation include large mucosal resections and the resection of multiple lesions on the initial procedure.
Barrett Esophagus
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Constriction, Pathologic
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Deglutition Disorders
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Endoscopy
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Esophageal Stenosis*
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Follow-Up Studies
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Humans
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Logistic Models
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Prospective Studies
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Retrospective Studies
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Risk Factors
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Tertiary Care Centers