2.Teleophthalmology and its evolving role in a COVID-19 pandemic: A scoping review.
Jiamin Charmaine CHONG ; Chai-Hoon Nowel TAN ; David Z CHEN
Annals of the Academy of Medicine, Singapore 2021;50(1):61-76
INTRODUCTION:
Teleophthalmology may assist the healthcare sector in adapting to limitations imposed on clinical practice by a viral pandemic. A scoping review is performed in this study to assess the current applications of teleophthalmology for its suitability to diagnose, monitor or manage ophthalmological conditions with accuracy.
METHODS:
A search of PubMed was conducted for teleophthalmology-related articles published from 1 January 2018 to 4 May 2020. Only articles that focused on the use of teleophthalmology in terms of diagnosis and management, as well as its benefits and detriments, were included. The Mixed Methods Appraisal Tool (MMAT) was used to assess the quality of the included articles.
RESULTS:
A total of 38 articles were assessed at the full-text level. There were 2 qualitative studies and 1 quantitative randomised controlled trial, while the majority were either quantitative descriptive studies (19, 50.0%) or quantitative non-randomised studies (16, 42.1%). Overall, 8 studies described reducing manpower requirements, 4 described reducing direct patient-doctor contact, 17 described storage of medical imaging and clinical data, and 9 described real-time teleconferencing. The MMAT analysis revealed limitations in appropriate sampling strategy in both quantitative non-randomised studies (9 of 16, 56.3%) and quantitative descriptive studies (9 of 19, 47.4%). Cost-effectiveness of teleophthalmology was not performed in any included study.
CONCLUSION
This current review of the various aspects of teleophthalmology describes how it may potentially assist the healthcare sector to cope with the limitations imposed by a viral pandemic through technology. Further research is required to evaluate the cost-effectiveness of the various strategies.
COVID-19/transmission*
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Humans
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Ophthalmology/organization & administration*
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Telemedicine/organization & administration*
3.Development and Validation of an Attitudinal-Profiling Tool for Patients With Asthma.
Aileen DAVID-WANG ; David PRICE ; Sang Heon CHO ; James Chung Man HO ; Chong Kin LIAM ; Glenn NEIRA ; Pei Li TEH
Allergy, Asthma & Immunology Research 2017;9(1):43-51
PURPOSE: To develop a profiling tool which accurately assigns a patient to the appropriate attitudinal cluster for the management of asthma. METHODS: Attitudinal data from an online survey of 2,467 patients with asthma from 8 Asian countries/region, aged 18-50 years, having had ≥2 prescriptions in the previous 2 years and access to social media was used in a discriminant function analysis to identify a minimal set of questions for the Profiling Tool. A split-sample procedure based on 100 sets of randomly selected estimation and validation sub-samples from the original sample was used to cross-validate the Tool and assess the robustness of its predictive accuracy. RESULTS: Our Profiling Tool contained 10 attitudinal questions for the patient and 1 GINA-based level of asthma control question for the physician. It achieved a predictive accuracy of 76.2%. The estimation and validation sub-sample accuracies of 76.7% and 75.3%, respectively, were consistent with the tool's predictive accuracy at 95% confidence level; and their 1.4 percentage-points difference set upper-bound estimate for the degree of over-fitting. CONCLUSIONS: The Profiling Tool is highly predictive (>75%) of the attitudinal clusters that best describe patients with asthma in the Asian population. By identifying the attitudinal profile of the patient, the physician can make the appropriate asthma management decisions in practice. The challenge is to integrate its use into the consultation workflow and apply to areas where Internet resources are not available or patients who are not comfortable with the use of such technology.
Asia
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Asian Continental Ancestry Group
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Asthma*
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Discriminant Analysis
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Disease Management
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Humans
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Internet
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Prescriptions
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Social Media
4.First report of the signal fly, Scholastes sp. (Diptera:Platystomatidae) visiting animal carcasses in Malaysia.
Chen Chee Dhang ; Chong Chin Heo ; David McAlpine ; Hiromu Kurahashi ; Nazni Wasi Ahmad ; Abdullah Marwi Mohamad ; John Jeffery ; Lee Han Lim ; Baharudin Omar ; Mohd Sofian-Azirun
Tropical biomedicine 2008;25(3):264-6
Signal fly, Scholastes sp. (Diptera: Platystomatidae) was observed associated with animal carcasses in Malaysia. The first observation was on a monkey carcass, which was killed by using a handgun and immediately placed in a forested area in Gombak, Selangor while the second observation was on a pig that died of natural causes and whose carcass was placed in an oil palm plantation in Tanjung Sepat, Selangor. Both animal carcasses were visited by Scholastes sp. flies during the fresh decomposition period. However, the role Scholastes flies in the decomposition process remains unknown. In this paper, we report the occurrence of Scholastes sp. on animal carcasses in Malaysia for the first time.
Diptera
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Animals
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Malaysia
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Patient observation
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First
5.Prevalence and Incidence of Epilepsy in an Elderly and Low-Income Population in the United States.
Derek H TANG ; Daniel C MALONE ; Terri L WARHOLAK ; Jenny CHONG ; Edward P ARMSTRONG ; Marion K SLACK ; Chiu Hsieh HSU ; David M LABINER
Journal of Clinical Neurology 2015;11(3):252-261
BACKGROUND AND PURPOSE: The purpose of this study was to estimate the incidence and prevalence of epilepsy among an elderly and poor population in the United States. METHODS: Arizona Medicaid claims data from January 1, 2008 to December 31, 2010 were used for this analysis. Subjects who were aged > or =65 years and were continuously enrolled in any Arizona Medicaid health plans (eligible to patients with low income) for > or =12 months between January 1, 2008 and December 31, 2009 were considered eligible for inclusion in the study cohort. In addition to meeting the aforementioned criteria, incident and prevalent cases must have had epilepsy-related healthcare claims. Furthermore, incident cases were required to have a 1-year "clean" period immediately preceding the index date. Negative binomial and logistic regression models were used to assess the factors associated with epilepsy incidence and prevalence. RESULTS: The estimated epilepsy incidence and prevalence for this population in 2009 were 7.9 and 19.3 per 1,000 person-years, respectively. The incidence and prevalence rates were significantly higher for patients with comorbid conditions that were potential risk factors for epilepsy and were of younger age than for their non-comorbid and older counterparts (p<0.05). The prevalence rates were significantly higher for non-Hispanic Blacks and male beneficiaries than for non-Hispanic Whites and female beneficiaries, respectively (p<0.05). CONCLUSIONS: This patient population had higher epilepsy incidence and prevalence compared with the general US population. These differences may be at least in part attributable to their low socioeconomic status.
African Continental Ancestry Group
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Aged*
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Arizona
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Cohort Studies
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Delivery of Health Care
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Epilepsy*
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Female
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Humans
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Incidence*
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Logistic Models
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Male
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Medicaid
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Poverty*
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Prevalence*
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Risk Factors
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Social Class
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United States*
6.Causes and assessment of subacute and chronic wrist pain.
Janice Chin-Yi LIAO ; Alphonsus Khin Sze CHONG ; David Meng Kiat TAN
Singapore medical journal 2013;54(10):592-quiz 598
Wrist pain is a common presentation to the general practitioner and emergency department. Most cases are simple to treat, and pain frequently resolves with conservative treatment. However, there are certain conditions, such as scaphoid nonunion and Kienböck's disease, where delayed diagnosis and treatment can result in long-term deformity or disability. This article covers the various causes of wrist pain, recommendations on how wrist pain should be assessed, as well as details some of the common conditions that warrant specialist referral.
Acute Pain
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diagnosis
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etiology
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rehabilitation
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Arthralgia
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diagnosis
;
etiology
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rehabilitation
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Chronic Pain
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diagnosis
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etiology
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rehabilitation
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Disability Evaluation
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Fractures, Ununited
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complications
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diagnosis
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Humans
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Orthopedic Procedures
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methods
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Osteonecrosis
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complications
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diagnosis
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Pain Measurement
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Scaphoid Bone
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injuries
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Wrist Injuries
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complications
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diagnosis
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rehabilitation
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Wrist Joint
7.Projection of Eye Disease Burden in Singapore.
John P ANSAH ; Victoria KOH ; Dirk F de KORNE ; Steffen BAYER ; Chong PAN ; Jayabaskar THIYAGARAJAN ; David B MATCHAR ; Ecosse LAMOUREUX ; Desmond QUEK
Annals of the Academy of Medicine, Singapore 2018;47(1):13-28
INTRODUCTIONSingapore's ageing population is likely to see an increase in chronic eye conditions in the future. This study aimed to estimate the burden of eye diseases among resident Singaporeans stratified for age and ethnicity by 2040.
MATERIALS AND METHODSPrevalence data on myopia, epiretinal membrane (ERM), retinal vein occlusion (RVO), age macular degeneration (AMD), diabetic retinopathy (DR), cataract, glaucoma and refractive error (RE) by age cohorts and educational attainment from the Singapore Epidemiology of Eye Diseases (SEED) study were applied to population estimates from the Singapore population model.
RESULTSAll eye conditions are projected to increase by 2040. Myopia and RE will remain the most prevalent condition, at 2.393 million (2.32 to 2.41 million) cases, representing a 58% increase from 2015. It is followed by cataract and ERM, with 1.33 million (1.31 to 1.35 million), representing an 81% increase, and 0.54 million (0.53 to 0.549 million) cases representing a 97% increase, respectively. Eye conditions that will see the greatest increase from 2015 to 2040 in the Chinese are: DR (112%), glaucoma (100%) and ERM (91.4%). For Malays, DR (154%), ERM (136%), and cataract (122%) cases are expected to increase the most while for Indians, ERM (112%), AMD (101%), and cataract (87%) are estimated to increase the most in the same period.
CONCLUSIONResults indicate that the burden for all eye diseases is expected to increase significantly into the future, but at different rates. These projections can facilitate the planning efforts of both policymakers and healthcare providers in the development and provision of infrastructure and resources to adequately meet the eye care needs of the population. By stratifying for age and ethnicity, high risk groups may be identified and targeted interventions may be implemented.
8.Effect of location of out-of-hospital cardiac arrest on survival outcomes.
E Shaun GOH ; Benjamin LIANG ; Stephanie FOOK-CHONG ; Nur SHAHIDAH ; Swee Sung SOON ; Susan YAP ; Benjamin LEONG ; Han Nee GAN ; David FOO ; Lai Peng THAM ; Rabind CHARLES ; Marcus E H ONG
Annals of the Academy of Medicine, Singapore 2013;42(9):437-444
INTRODUCTIONThis study aims to study how the effect of the location of patient collapses from cardiac arrest, in the residential and non-residential areas within Singapore, relates to certain survival outcomes.
MATERIALS AND METHODSA retrospective cohort study of data were done from the Cardiac Arrest and Resuscitation Epidemiology (CARE) project. Out-of- hospital cardiac arrest (OHCA) data from October 2001 to October 2004 (CARE) were used. All patients with OHCA as confirmed by the absence of a pulse, unresponsiveness and apnoea were included. All events had occurred in Singapore. Analysis was performed and expressed in terms of the odds ratio (OR) and the corresponding 95% confidence interval (CI).
RESULTSA total of 2375 cases were used for this analysis. Outcomes for OHCA in residential areas were poorer than in non-residential areas-1638 (68.9%) patients collapsed in residential areas, and 14 (0.9%) survived to discharge. This was significantly less than the 2.7% of patients who survived after collapsing in a non-residential area (OR 0.31 [0.16 - 0.62]). Multivariate logistic regression analysis showed that location alone had no independent effect on survival (adjusted OR 1.13 [0.32 - 4.05]); instead, underlying factors such as bystander CPR (OR 3.67 [1.13 - 11.97]) and initial shockable rhythms (OR 6.78 [1.95 - 23.53]) gave rise to better outcomes.
CONCLUSIONEfforts to improve survival from OHCA in residential areas should include increasing CPR by family members, and reducing ambulance response times.
Adult ; Aged ; Aged, 80 and over ; Ambulances ; Cardiopulmonary Resuscitation ; statistics & numerical data ; Cohort Studies ; Emergency Medical Services ; statistics & numerical data ; Female ; Geography ; Humans ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Odds Ratio ; Out-of-Hospital Cardiac Arrest ; mortality ; Residence Characteristics ; statistics & numerical data ; Retrospective Studies ; Singapore ; epidemiology ; Time-to-Treatment ; statistics & numerical data ; Treatment Outcome
9.Predictors of failure following fixation of intertrochanteric fractures with proximal femoral nail antirotation.
Raghavan RAGHURAMAN ; Jia Wen KAM ; David Thai Chong CHUA
Singapore medical journal 2019;60(9):463-467
INTRODUCTION:
This retrospective matched case-control study aimed to identify predictors of cut-out following intramedullary nailing of intertrochanteric fractures with the 200-mm Synthes proximal femoral nail antirotation (PFNA).
METHODS:
609 patients underwent intramedullary nailing for intertrochanteric fractures at our institution between January 2011 and December 2014. 370 patients satisfied the inclusion criteria. There were 20 cases of implant cut-out. Cases and controls were matched using a propensity score-matching method with an m:n ratio, matching the criteria of gender, age and side of operation. Radiographs were assessed to determine fracture classification, fracture reduction quality, tip-apex distance, calcar referenced tip-apex distance (CalTAD), anteroposterior (AP) Parker's ratio index, lateral Parker's ratio index and cervical angle difference. Conditional logistic regression analysis was performed to determine any association between potential predictors and cut-outs.
RESULTS:
The cut-out incidence was 5.4%. Of the 20 cut-outs, 16 were superior and four were cut-throughs. Univariate analysis only showed a significant association between unsatisfactory fracture reduction quality and cut-outs (odds ratio [OR] 10.1, 95% confidence interval [CI] 1.31-77.6, p = 0.027). This association remained significant with multivariate logistic regression analysis (OR 16.4, 95% CI 1.9-140.4, p = 0.011). Cut-throughs had significantly lower CalTAD (16.2 vs. 27.5, p = 0.016) and AP Parker's ratio index values (38.7 vs. 50.7, p = 0.007) than superior cut-outs.
CONCLUSION
Unsatisfactory fracture reduction quality was a significant predictor of cut-out in intertrochanteric fractures treated with the 200-mm PFNA. Cut-outs had two distinct modes, with cut-throughs having a deeper and more inferior helical blade position in the femoral head compared to superior cut-outs.
10.Multidisciplinary perspectives on newly revised 2018 FIGO staging of cancer of the cervix uteri
Jonathan S BEREK ; Koji MATSUO ; Brendan H GRUBBS ; David K GAFFNEY ; Susanna I LEE ; Aoife KILCOYNE ; Gi Jeong CHEON ; Chong Woo YOO ; Lu LI ; Yifeng SHAO ; Tianhui CHEN ; Miseon KIM ; Mikio MIKAMI
Journal of Gynecologic Oncology 2019;30(2):e40-
No abstract available.
Uterine Cervical Neoplasms
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Uterus