OBJECTIVE: To report the possible malignant transformation of primary sinonasal ameloblastoma into sinonasal ameloblastic carcinoma.

METHODS
Design: Case Report

Setting: Tertiary Public University Hospital

Patient: One

RESULT: A 50-year-old woman with a previous diagnosis of sinonasal ameloblastoma reported recurrence of symptoms of right-sided nasal obstruction and epistaxis two years after endoscopic sinus surgery. Clinical examination, CT scans and subsequent total maxillectomy with orbital exenteration revealed a left intranasal mass with maxillary, ethmoid and orbital floor extension and pulmonary and hepatic metastases.  Histopathologic findings of palisading columnar epithelium with reverse polarity with malignant features were consistent with ameloblastic carcinoma. Despite subsequent cycles of chemotherapy, the patient died two years after surgery. To the best of our knowledge, there have been no published reports of a primary sinonasal ameloblastoma with malignant transformation in the English literature.

CONCLUSION: Ameloblastic carcinoma is a rare neoplasm which may arise de novo or from malignant transformation of an ameloblastoma. Because ameloblastoma is commonly encountered in our setting, clinicians should be aware of this possibility and closely follow their patients accordingly.

Human ; Female ; Middle Aged ; Carcinoma ; Ameloblastoma ; neoplasm ; Tomography Scanners, X-Ray Computed

Objective: To report the case of a rare benign odontogenic tumor in an adolescent girl which was successfully managed by complete excision and curettage of underlying bone. Methods: Design: Case Report. Setting: Tertiary National University Hospital. Patient: One. Result: A 15-year-old girl with a 3-year history of a large Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor) atypically occurring in the posterior maxillary alveolar ridge and compressing the maxillary antrum underwent tumor excision via gingivobuccal approach and curettage of the emaining mucosa in the cavity in consideration of her patient’s aesthetic concerns. No recurrence has been observed two years post-op and she remains asymptomatic on regular follow-up. Conclusion A calcifying epithelial odontogenic tumor can be managed conservatively with close follow-up to monitor recurrence.
Adolescent ; Calcifying Epithelial Odontogenic Tumor ; Odontogenic Tumors ; Skin Neoplasms

Introduction: Bamboo node is a rare vocal cord pathology causing dysphonia among patients with autoimmune disorders. These “bamboo-joint-like” transverse deposits on the vocal cords interfere with the vibratory cycle during phonation leading to voice hoarseness. A review of Schwemmle from 1993-2009, showed seven cases of bamboo node among patients with mixed connective tissue disease (MCTD). With the patient’s consent, this case is presented to contribute to current knowledge about MCTD. Case Presentation: A 36-year-old Filipino female developed voice hoarseness one year after she was diagnosed with MCTD. Videostroboscopic findings revealed bilateral bamboo nodes, vibratory defects, and amplitude abnormalities. Treatment with prednisone, methotrexate, hydroxychloroquine, along with voice rest and speech therapy resulted in normalization of amplitude, mucosal wave and vibratory behavior during repeat videostroboscopy. Conclusion To date, this is the first known case of bamboo nodes associated with MCTD in a Filipino patient. This case highlights the importance of properly investigating the symptom of hoarseness among patients with rheumatologic diseases. A multidisciplinary approach involving the rheumatologist, otorhinolaryngologist, and speech therapist play an important role in the complete care of this patient.
Dysphonia