1.An unexpected outcome following radial head excision for Jeffrey type II fracture-dislocation of the proximal radius in a child.
Annals of the Academy of Medicine, Singapore 2010;39(9):742-743
Child
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Humans
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Joint Dislocations
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surgery
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Male
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Orthopedic Procedures
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Radius
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injuries
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surgery
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Radius Fractures
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surgery
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Treatment Outcome
2.Revision total knee arthroplasty: causes and outcomes.
Kae Sian TAY ; Ngai Nung LO ; Seng Jin YEO ; Shi Lu CHIA ; Darren K J TAY ; Pak Lin CHIN
Annals of the Academy of Medicine, Singapore 2013;42(4):178-183
INTRODUCTIONLocal data on revision total knee arthroplasty (TKA) are limited. This study aims to assess the causes and outcomes of revision TKA in a single institution, with a 2-year follow-up.
MATERIALS AND METHODSA retrospective review of case records of patients who underwent revision TKA in 2008 and 2009 in the authors' institution was performed. Outcome was assessed using SF-36, Oxford knee score and Knee Society Clinical Rating System preoperatively, at 6 months and at 2 years' follow-up.
RESULTSForty-one patients (41 knees) were included in the study. Indications for revision were aseptic loosening in 13 (31.7%), mechanical wear/component failure in 10 (24.4%), infection in 9 (22.0%), malalignment in 4 (9.8%), instability in 3 (7.3%), periprosthetic fracture in 1 (2.4%) and persistent stiffness in 1 (2.4%). Significant improvements were seen postoperatively in all 3 instruments used to evaluate clinical outcome. These improvements were seen at 6 months after surgery, and were maintained through the 2-year follow-up period. There were no significant changes in all scores between 6 months and 2 years follow-up. There was 100% survivorship of the implants with no postoperative complications requiring surgical intervention.
CONCLUSIONIndications for revision TKA locally are similar to those in other large centres. Revision total knee arthroplasty results in significantly improved function and quality of life for patients, which is maintained over a 2-year follow-up period. In our series, we obtained 100% implant survivorship.
Aged ; Arthroplasty, Replacement, Knee ; Female ; Follow-Up Studies ; Humans ; Incidence ; Knee Prosthesis ; Male ; Middle Aged ; Osteoarthritis, Knee ; surgery ; Postoperative Complications ; epidemiology ; Prosthesis Failure ; Reoperation ; Retrospective Studies ; Singapore ; epidemiology ; Time Factors
3.Chronic Achilles tendon rupture treated with two turndown flaps and flexor hallucis longus augmentation - two-year clinical outcome.
Darren TAY ; Heng An LIN ; Benjamin Sa TAN ; Keen Wai CHONG ; Inderjeet Singh RIKHRAJ
Annals of the Academy of Medicine, Singapore 2010;39(1):58-60
INTRODUCTIONBoth conservative and operative management have been described in the literature for the management of chronic Achilles tendon ruptures with surgical management generally having more favourable results. In our institution, the favoured reconstructive technique was the use of 2 turndown tendon fl aps fashioned from the proximal Achilles tendon augmented by a tenomyodesis of the flexor hallucis longus. The purpose of this study was to assess the clinical outcome of all patients who underwent this procedure.
MATERIALS AND METHODSFrom the records, a total of 9 patients underwent the above-mentioned procedure of whom 6 patients had complete data collection sets [including SF-36, Visual Analogue Scale (VAS), American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot scores, ankle range of motion (ROM), presence of residual symptoms and complications] at 2 years of follow-up.
RESULTSOur results showed an average AOFAS Ankle-Hindfoot score of 94.2, VAS of 0 in all but 1 patient, and generally high scores (75-96) in all 8 domains of the SF-36 questionnaire. Patient satisfaction was also rated to be high from the surgical procedure.
CONCLUSIONWe submit that the procedure adopted at our institution is able to reproduce satisfactory results with low morbidity in patients with this challenging condition.
Achilles Tendon ; injuries ; surgery ; Aged ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Muscle, Skeletal ; surgery ; Orthopedic Procedures ; methods ; rehabilitation ; Patient Satisfaction ; Recovery of Function ; Rupture ; surgery ; Suture Techniques ; Tendon Injuries ; surgery ; Tendons ; transplantation ; Transplantation, Autologous
4.Trauma and orthopaedics in the COVID-19 pandemic: breaking every wave.
Keng Jin Darren TAY ; Yee Han Dave LEE
Singapore medical journal 2020;61(8):396-398
Coronavirus Infections
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epidemiology
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prevention & control
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Elective Surgical Procedures
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statistics & numerical data
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Female
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Humans
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Infection Control
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methods
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Infectious Disease Transmission, Patient-to-Professional
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prevention & control
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Male
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Occupational Health
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statistics & numerical data
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Orthopedic Procedures
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methods
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statistics & numerical data
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Outcome Assessment, Health Care
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Pandemics
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prevention & control
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statistics & numerical data
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Patient Safety
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statistics & numerical data
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Pneumonia, Viral
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epidemiology
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prevention & control
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Risk Assessment
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Safety Management
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Singapore
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Wounds and Injuries
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diagnosis
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epidemiology
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surgery
5.Predictors of Midterm Outcomes after Medial Unicompartmental Knee Arthroplasty in Asians.
Hamid Rahmatullah BIN ABD RAZAK ; Sanchalika ACHARYYA ; Shi Ming TAN ; Hee Nee PANG ; Keng Jin Darren TAY ; Shi Lu CHIA ; Ngai Nung LO ; Seng Jin YEO
Clinics in Orthopedic Surgery 2017;9(4):432-438
BACKGROUND: This study was designed to evaluate predictors of good outcomes following medial unicompartmental knee arthroplasty (UKA) in Asian patients. METHODS: Registry data of patients who underwent primary unilateral medial UKA from 2006 to 2011 were collected. Outcomes studied were the Oxford Knee Score (OKS) and the Physical Component Score (PCS) of the Short Form 36 (SF-36) questionnaire. These outcome scores were collected prospectively, pre- and postoperatively up to 5 years. Good outcome was defined as an overall improvement in score greater than or equal to the minimal clinically important difference (MCID). The MCID for the OKS was 5 while the MCID for the PCS was 10. Regression analysis was used to identify predictors of good outcomes following medial UKA. RESULTS: Primary medial UKA was performed in 1,075 patients. Higher (poorer) preoperative OKS (odds ratio [OR], 1.27; p < 0.001), lower (poorer) preoperative PCS (OR, 1.08; p < 0.001), lower (poorer) preoperative Knee Society Knee Score (KSKS; OR, 1.02; p < 0.001) and higher (better) preoperative SF-36 Mental Component Score (MCS; OR, 1.02; p < 0.001) were significant predictors of good outcomes. CONCLUSIONS: Patients with poorer OKS, PCS and KSKS and better SF-36 MCS preoperatively tended to achieve good outcomes by the MCID criterion at 5 years following the index surgery.
Arthroplasty
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Arthroplasty, Replacement, Knee*
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Asia
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Asian Continental Ancestry Group*
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Humans
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Knee
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Osteoarthritis
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Prospective Studies
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Registries
6.Early experiences with robot-assisted total knee arthroplasty using the DigiMatch™ ROBODOC® surgical system.
Ming Han Lincoln LIOW ; Pak Lin CHIN ; Keng Jin Darren TAY ; Shi Lu CHIA ; Ngai Nung LO ; Seng Jin YEO
Singapore medical journal 2014;55(10):529-534
INTRODUCTIONThe use of robotics in total knee arthroplasty (TKA) has been shown to minimise human error, as well as improve the accuracy and precision of component implantation and mechanical axis alignment. The present study aimed to demonstrate that robot-assisted TKA using ROBODOC® is safe and capable of producing a consistent and accurate postoperative mechanical axis.
METHODSWe prospectively recruited 27 consecutive patients who underwent robot-assisted TKA between May and December 2012. Two patients were excluded from the study due to intraoperative technical problems with the robot. Long-leg radiography and computed tomography were performed prior to surgery, and used for mechanical axis measurements and component sizing. DigiMatch™ ROBODOC® Surgical System software version 4.3.6 (Curexo Technology Corp, Fremont, CA, USA) was used in all cases to perform bone cuts in accordance with the preoperative plan.
RESULTSThe postoperative coronal mechanical alignment was within 3 degrees, with a mean alignment of -0.4 ± 1.7 degrees, confirming the accuracy of the preoperative surgical plan and bone cuts. The mean operating time was 96 ± 15 min, and preoperative planning yielded 100% implant sizing accuracy.
CONCLUSIONRobotics has the potential to enable surgeons to consistently attain ideal postoperative alignment. The use of bone movement monitors and an integrated navigation system enhances the safety profile of ROBODOC® by minimising errors. However, the role of the surgeon in TKA is still vital, as the surgeon is ultimately in charge of planning the surgery, its execution and ensuring soft tissue balance during TKA.
Aged ; Arthroplasty, Replacement, Knee ; instrumentation ; Female ; Humans ; Knee Joint ; diagnostic imaging ; Male ; Middle Aged ; Prospective Studies ; Robotic Surgical Procedures ; instrumentation ; Tibia ; surgery ; Tomography, X-Ray Computed
7.Reducing allograft contamination and disease transmission: intraosseous temperatures of femoral head allografts during autoclaving.
Chay-You ANG ; Andy Khye-Soon YEW ; Darren Keng-Jin TAY ; Shi-Lu CHIA ; Seng-Jin YEO ; Ngai-Nung LO ; Pak-Lin CHIN
Singapore medical journal 2014;55(10):526-528
INTRODUCTIONThe Singapore General Hospital Bone Bank, which exclusively stores femoral head allografts, relies on flash sterilisation to prevent allograft-related disease transmission and wound infection. However, intraosseous temperatures during autoclaving may be lower than required to eliminate human immunodeficiency virus, and hepatitis B and C viruses. The aim of this study is to determine the intraosseous temperatures of femoral head allografts during autoclaving and to assess the adequacy of autoclaving in preventing disease transmission.
METHODSSix femoral heads were acquired from patients who underwent hip arthroplasty. The specimens were divided into two groups. The first group underwent flash sterilisation with a sterilisation time of 4 min, while a longer sterilisation time of 22 min was used for the second group.
RESULTSThe highest core temperature in the first group was 130°C, while the core temperatures in the second group plateaued at 133°C for all allografts. In the first group, only smaller allografts maintained temperatures sufficient for the inactivation of the clinically relevant viral pathogens. In contrast, all allografts in the second group were terminally sterilised.
CONCLUSIONThere is an inverse correlation between the size of allografts and intraosseous temperatures achieved during autoclaving. Therefore, we recommend dividing large allografts into smaller pieces, in order to achieve intraosseous temperatures adequate for the elimination of transmissible pathogens during flash sterilisation. Allografts should not be terminally sterilised, as the resulting allografts will become unusable. Despite modern processing techniques, stringent donor selection remains vital in the effort to prevent allograft-related infections. Autoclaving is an economical and efficacious method of preventing allograft-related disease transmission.
Allografts ; Blood-Borne Pathogens ; Bone Transplantation ; instrumentation ; Disease Transmission, Infectious ; prevention & control ; Disinfection ; methods ; standards ; Equipment Contamination ; prevention & control ; Femur Head ; microbiology ; transplantation ; Humans ; Sterilization ; methods ; Temperature
8.Non-alcoholic fatty liver disease increases risk of carotid atherosclerosis and ischemic stroke: An updated meta-analysis with 135,602 individuals
Ansel Shao Pin TANG ; Kai En CHAN ; Jingxuan QUEK ; Jieling XIAO ; Phoebe TAY ; Margaret TENG ; Keng Siang LEE ; Snow Yunni LIN ; May Zin MYINT ; Benjamin TAN ; Vijay K SHARMA ; Darren Jun Hao TAN ; Wen Hui LIM ; Apichat KAEWDECH ; Daniel HUANG ; Nicholas WS CHEW ; Mohammad Shadab SIDDIQUI ; Arun J SANYAL ; Mark MUTHIAH ; Cheng Han NG
Clinical and Molecular Hepatology 2022;28(3):483-496
Background/Aims:
Non-alcoholic fatty liver disease (NAFLD) is associated with the development of cardiovascular disease. While existing studies have examined cardiac remodeling in NAFLD, there has been less emphasis on the development of carotid atherosclerosis and stroke. We sought to conduct a meta-analysis to quantify the prevalence, risk factors, and degree of risk increment of carotid atherosclerosis and stroke in NAFLD.
Methods:
Embase and Medline were searched for articles relating to NAFLD, carotid atherosclerosis, and stroke. Proportional data was analysed using a generalized linear mixed model. Pairwise meta-analysis was conducted to obtain odds ratio or weighted mean difference for comparison between patients with and without NAFLD.
Results:
From pooled analysis of 30 studies involving 7,951 patients with NAFLD, 35.02% (95% confidence interval [CI], 27.36–43.53%) had carotid atherosclerosis with an odds ratio of 3.20 (95% CI, 2.37–4.32; P<0.0001). Pooled analysis of 25,839 patients with NAFLD found the prevalence of stroke to be 5.04% (95% CI, 2.74–9.09%) with an odds ratio of 1.88 (95% CI, 1.23–2.88; P=0.02) compared to non-NAFLD. The degree of steatosis assessed by ultrasonography in NAFLD was closely associated with risk of carotid atherosclerosis and stroke. Older age significantly increased the risk of developing carotid atherosclerosis, but not stroke in NAFLD.
Conclusions
This meta-analysis shows that a stepwise increment of steatosis of NAFLD can significantly increase the risk of carotid atherosclerosis and stroke development in NAFLD. Patients more than a third sufferred from carotid atherosclerosis and routine assessment of carotid atherosclerosis is quintessential in NAFLD.