1.Controllable bio-fabrication based on microbes.
Xudian SHI ; Gang WANG ; Darning WANG ; Longjiang YU ; Guang YANG
Chinese Journal of Biotechnology 2009;25(6):909-913
Microorganisms in nature have rich variety, whose sizes are from nano scale to micro scale. Therefore, microbes can be used as natural "building blocks" in nano/micro multi-level fabrication processes. At present, most of the bio-manufacturing methods do not apply to direct control of living microbes. Their microbiological global functions and superiorities are not available. In this paper, two novel nano/micro bio-fabrication approaches, micro-fluidic control method and magnetic control method have been established. The living microbes could be manipulated to form micro-scaled patterns or to move orientedly. By these approaches, living microbes are taken as nano/micro robots. We could employ their specific biological functions and regulate their controllable self-assembly, which is expected to design and create a series of new special functional materials and devices.
Bacteria
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metabolism
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Biomimetics
;
methods
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Biotechnology
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Fungi
;
metabolism
;
Gluconacetobacter xylinus
;
metabolism
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Industrial Microbiology
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Microfluidic Analytical Techniques
;
methods
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Microtubules
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Nanotechnology
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Saccharomyces cerevisiae
;
metabolism