1.Observation and nursing of propofol combined with tramadol on gastroscope detection in hypertension patients
Feng-Qin LI ; Xia LU ; Xiao-Ying SUN ; Dao-Hong NIE
Chinese Journal of Modern Nursing 2010;16(6):646-648
Objective To explore the application and nursing of propofol combined with tramadol on gastroscope detection in patients with hypertension.Methods One hundred and twenty cases with hypertension undergoing gastroscope detection were randomly divided into 2 groups.Sixty cases of study group were injected with propofol and tramadol while the other 60 cases of control group received routine method.HR, SBP, DBP, SPO2 and other indictors were recorded during gastroscope detection and the data were analyzed.Results HR, SBP, and DBP in study group were significantly lower than in control group (P <0.01) , but there were no difference in SpCO2 .Conclusions The combination of propofol and tramadol is safe and effective on gastroscope detection in hypertension patients.Intensive monitor and nursing are very important in the process of gastroscope detection.
2.Development and Application of Automatic Analysis and Surveillance Platform for Chrimerism in Donors and Recipients after Allo-HSCT.
Jian-Cheng FANG ; Fang WANG ; Li-Li YUAN ; Mian-Mian WANG ; Ting-Ting LI ; Yi-Hang YANG ; Yang LIU ; Xiao-Li MA ; Xue CHEN ; Yang ZHANG ; Dai-Jing NIE ; Jia-Qi CHEN ; Hong-Xing LIU
Journal of Experimental Hematology 2020;28(3):1012-1018
OBJECTIVE:
To develop an automated chimeric analysis and reporting platform based on short tandem repeat (STR) and capillary electrophoresis methods for allogeneic hematopoietic stem cell transplantation (allo-HSCT) so as to improve work efficiency.
METHODS:
Apache, MySQL, PHP and HTML5 were used to build the database and interface. The STR locus geno typing and chimeric analysis logic and flow were set up on the basis of STR rules and capillary electrophoresis. STR genotyping and 194 times of chimeric testing data of 100 patients after allo-HSCT were used to test the platform for automatic STR locus genotyping, chimeric calculation and report generation.
RESULTS:
The established platform could realize the functions of STR locus customization, STR genotype determination, automatic chimeric analysis, and detection information database management, which can automatically generate an integrated report including multiple sequential chimeric results and trend graphs for the same patient and can be accessed and used simultaneously by different users through different browser interfaces. The results of automated analysis by the platform are completely consistent with that of manual analysis by experienced technicians, and the possibility of manual analysis error is reduced through automation. The time required for automatic analysis using this platform is approximately 1/6-1/5 of manual analysis.
CONCLUSION
The automatic analysis platform built in this study is operation stable and reliable in analysis results, which can improve work efficiency and report connotation, thus worthing popularized and applicable.
Electrophoresis, Capillary
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Genotype
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Hematopoietic Stem Cell Transplantation
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Humans
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Microsatellite Repeats
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Tissue Donors