Construction of excellent course provides students with modern educational resources.Construction was focused on one main line,two dimensions,three aspects and with building frame,filling columns,putting into use,collecting feedback as well as modification and updating.Analysis was further made to avoid the common problems and phenomena such as displayed pages,limitation of share resources,low utilization of teaching resources and emphasis on construction,ignoring application and neglecting management.Some measures such as increasing the guidance of excellent courses and their promotion efforts,the establishment of an exchange platform and listening to feedback etc.are proposed.

It is important to bring the principal role of medical students into full play and to develop their learning motivation and enthusiasm in order to obtain the satisfactory teaching effect in the clinical practice of preventive medicine and pediatric dentistry.Methods of timely summing-up,self-evaluation,making assumption and pair combination should be recommended.Cultivation for medical students should focus on the idea for diagnosis and treatment,skill of clinical practice and ability of doctor-patient communication.

Smart dressings, which show obvious advantage and potential in wound treatment and real-time monitoring, attract widespread attention in recent years. Real-time and dynamic acquiring wound information is vital to the treatment and prognosis of wound. Further research on smart dressings is helpful for wound management, personalized treatment, and realization of medical application translation of health monitoring technology. In the article, we categorize smart dressings and conclude their functions according to the type of micro-environment information of wound gathered by smart dressings.

Objective? To explore burden on family caregivers of elderly patients with chronic obstructive pulmonary disease (COPD) and to discuss the influencing factors of caregiver burden. Methods? Totally 190 family caregivers of elderly COPD patients treated in a Class III Grade A hospital in a city between January and December 2017 were selected by convenient sampling. The caregiver burden of these elderly COPD patients were investigated with the general information questionnaire, Zarit Burden Interview (ZBI) and Social Support Rating Scale (SSRS). Multiple linear regression analysis was used to analyze the influencing factors to caregiver burden. Results? The total score of caregiver burden of elderly COPD patients was (52.32±7.42), and the total score of social support was (25.23±5.93). Multiple linear regression analysis showed that age, occupation, time of daily care,medical service availability and social support were the main influencing factors to caregiver burden (P＜ 0.05). Conclusions? The caregiver burden of elderly COPD patients is at a medium level and is affected by multiple factors. More disease and nursing care related knowledge and information should be provided to the caregivers based on their actual conditions so as to improve the social support for caregivers as well as the caregivers' physiological and mental health and their quality of life.

Background and Objectives: p21, an important member of the Cip/Kip family, is involved in inhibitory effects of RUNX1b overexpression during the early stage of human hematopoiesis. Methods: and Results: We established a human embryonic stem cell (hESC) line with inducible expression of p21 (p21/hESCs). Overexpression of p21 did not influence either mesoderm induction or emergence of CD34＋ cells, but it significantly decreased the production of CD43＋ cells and changed the expression profile of hematopoiesis-related factors, leading to the negative effects of p21 on hematopoiesis. Conclusions In RUNX1b/hESC co-cultures when RUNX1b was induced from D0, perturbation of the cell cycle caused by upregulation of p21 probably prevented the appearance of CD43＋ cells, but not CD34＋ cells. The mechanisms via which CD34＋ cells are blocked by RUNX1b overexpression remain to be elucidated.