1.Research Progress on the Regulation of Inflammatory Microenvironment of Endometriosis by Chinese Medicine Based on the Theory of"Same Disease of Blood and Water"
Weilin ZHENG ; Zhiyi FU ; Danting WEN ; Hao LIU ; Lixing CAO
Traditional Chinese Drug Research & Clinical Pharmacology 2024;35(6):928-934
Endometriosis(EMs)is a chronic inflammatory disease.It has been proved that inflammatory microenvironment is the key role in EMs occurance and development.Chinese medicine posits that the theory of"same disease of blood and water",which generally refers to"intermingling dampness and blood stasis",serves as a crucial pathogenesis in EMs.The inflammatory microenvironment is the main manifestation of dampness and blood stasis in EMs,while the insufficiency of vital qi results in endogenous dampness.The stagnation of blood stasis serves as the foundation for the formation of intermingling dampness and blood stasis.Based on contemporary theories in molecular biology,the macrophage-mediated inflammatory microenvironment serves as the foundation for the formation of dampness,while the participation of macrophages in angiogenesis is crucial for the formation of blood stasis.Investigating the intrinsic connection between the inflammatory microenvironment in EMs and the theory of"same disease of blood and water"can contribute to a better understanding of the pathogenesis of EMs from a novel perspective.Remodeling of the inflammatory microenvironment in endometriosis by targeting macrophages may provide a new strategy for EMs treatment.
2.Expert Consensus on the Application of Traditional Chinese Medicine in the Treatment of Cervical Cancer Related Complications
Jiamin LIU ; Siyu WU ; Liner CAI ; Hong TANG ; Danting WEN ; Xiujun ZHU ; Xiangdan HU ; Ping XIE ; Jing XIAO
World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(7):1688-1697
Cervical cancer is the leading cause of cancer death in women in the developing countries.The treatment based on surgery,radiotherapy and chemotherapy is often accompanied by intolerable complications.Clinical practice has proved that TCM therapy has a positive effect on the complications related to the treatment of cervical cancer,but there is still a lack of scientific and standardized application reference opinions.Based on Delphi method,our research group constructed and formulated an expert consensus study on the complications related to the treatment of cervical cancer with TCM therapies,so as to provide a reference for clinical treatment of such diseases.