1.Two novel compounds from Ardisia punctata Lindl.
Chun LI ; Dang-Kun YUE ; Peng-Bin BU ; You-Fu SUN
Acta Pharmaceutica Sinica 2007;42(9):959-963
To study the chemical constituents of Ardisia punctata, compounds were isolated with a combination of multi-chromatography. Their structures were determined on the basis of spectral analysis and comparison to those of the known compounds. A 1,4-benzoquinone derivative and a alkylphenol were isolated from the petroleum ether extract of the roots of Ardisia punctata. Their structures were elucidated as 2-tridecyl-3-[(2-tridecyl-4-acetoxy-6-methoxy)-phenoxyl] -6-methoxy-1,4-benzoquinone (1) and 2-methoxy-4-hydroxy-6-tridecyl-phenyl acetate (2). The two compounds are both new.
Ardisia
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chemistry
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Benzoquinones
;
chemistry
;
isolation & purification
;
Molecular Structure
;
Phenylacetates
;
chemistry
;
isolation & purification
;
Plant Roots
;
chemistry
;
Plants, Medicinal
;
chemistry
2.Chemical constituents from roots of Ardisia punctata.
Chun LI ; Dang-Kun YUE ; Peng-Bin BU ; You-Fu SUN
China Journal of Chinese Materia Medica 2006;31(7):562-565
OBJECTIVETo study the chemical constituents from the roots of Ardisia punctata.
METHODCompounds were isolated by chromatographic techniques on silica gel and Rp-HPLC column. Their structures were elucidated by chemical and spectroscopic methods.
RESULTTwelve compounds were identified as 3-hydroxy-5-tridecyl-methyl phenyl ether (1), 5-pentadecyl-1, 3-benzenediol (2), 2-methoxy-6-tridecyl-1, 4-benzoquinone (3), 2-methoxy-6-pentadecyl-1, 4-benzoquinone (4), glutinol (5), ardisicrenoside A (6), ardisiacrispin B (7), 24-ethyl-5a-cholesta-7, 22(E)-dien-3-one (8), 24-ethyl-5alpha-cholesta-7, 22(E)-dien-3beta-ol (9), daucosterol (10), vanillin acid (11), tetratriacontanoic acid (12).
CONCLUSIONAll the compounds were obtained from this plant for the first time.
Ardisia ; chemistry ; Benzoquinones ; chemistry ; isolation & purification ; Oleanolic Acid ; analogs & derivatives ; chemistry ; isolation & purification ; Plant Roots ; chemistry ; Plants, Medicinal ; chemistry ; Saponins ; chemistry ; isolation & purification ; Triterpenes ; chemistry ; isolation & purification
3.Three new belamcandaquinones from Ardisia punctata.
Chun LI ; Dang-kun YUE ; Peng-bin BU ; You-fu SUN
Acta Pharmaceutica Sinica 2006;41(9):830-834
AIMTo study the chemical constituents of Ardisia punctata.
METHODSCompounds were separated with a combination of multi-chromatography. Their chemical structures were determined on the basis of spectral analysis and single crystal X-ray diffraction.
RESULTSThree compounds were isolated from chloroform extract of the roots of Ardisia punctata. Their structures were elucidated as 2-tridecyl-3-[(2-tridecyl-3-acetoxy-4-methoxy-6-hydroxy) -phenyl]-6-methoxy-1, 4-benzoquinone (1), 2-tridecyl-3-[(2-tridecyl-4,6-dihydroxy) -phenyl]-6-methoxy-1,4-benzoquinone (2) and 2-tridecyl-3-[(2-pentadecyl-4,6-dihydroxyl) -phenyl]-6-methoxy-,4-benzoquinone (3).
CONCLUSIONThe three compounds are new 1,4-benzoquinone derivatives.
Ardisia ; chemistry ; Benzoquinones ; chemistry ; isolation & purification ; Molecular Conformation ; Molecular Structure ; Phenols ; chemistry ; isolation & purification ; Plant Roots ; chemistry ; Plants, Medicinal ; chemistry ; Resorcinols ; chemistry ; isolation & purification
4.Chemical constituents from roots of Ficus hirta.
Chun LI ; Peng-Bin BU ; Dang-Kun YUE ; You-Fu SUN
China Journal of Chinese Materia Medica 2006;31(2):131-133
OBJECTIVETo study the chemical constituents from the roots of Ficus hirta.
METHODCompounds were isolated by chromatographic techniques on silica gel and HP-20 resin columns. Their structures were elucidated by chemical and spectroscopic methods.
RESULTTen compounds were identified as beta-sitosterol (1), stigmasterol (2), psoralene (3), 3beta-hydroxy-stigmast-5-en-7-one (4), 5-hydroxy-4', 6, 7, 8-tetramethoxy flavone (5), 4', 5, 6, 7, 8-pentamethoxy flavone (6), 4', 5, 7-trihydroxy-flavone (7), 3beta-acetoxy-beta-amyrin (8), 3beta-acetoxy-alpha-amyrin (9) and hesperidin (10).
CONCLUSIONThe compounds 4, 5, 6 were obtained from this genus for the first time, and all the compounds were obtained from this plant for the first time.
Ficus ; chemistry ; Ficusin ; chemistry ; isolation & purification ; Flavones ; chemistry ; isolation & purification ; Oleanolic Acid ; analogs & derivatives ; chemistry ; isolation & purification ; Plant Roots ; chemistry ; Plants, Medicinal ; chemistry ; Sitosterols ; chemistry ; isolation & purification ; Stigmasterol ; chemistry ; isolation & purification
5.Determination of acetylharpagide in Ajuga decumbens by HPLC.
Dang-Kun YUE ; Guang-Zhi DING ; Wei-Hao WANG ; Zhi-Min WANG ; Jian-Rong LI ; Yan TONG
China Journal of Chinese Materia Medica 2006;31(4):289-290
OBJECTIVETo establish a method of the quantitative determination of acetylharpagide in Ajuga decumbens.
METHODThe chromatographic conditions were as follows: a Phenomenex Luna C18 column was used, the mobile phase was composed of acetontrile-water (15:85), the flow rate was 1.0 mL x min(-1) and the UV absorbance detection was set at 197 nm.
RESULTLinearity of acetylharpagide was in the range of 0.6-3.6 microg (r = 0.9993), and the average recovery and RSD were 99.13% and 2.48%, respectively.
CONCLUSIONThe contents of acetylharpagide ranged 0.40%-6.39% in A. decumbens. The method was simple, accurate and sensitive.
Ajuga ; chemistry ; Chromatography, High Pressure Liquid ; methods ; Drugs, Chinese Herbal ; analysis ; Plants, Medicinal ; chemistry ; Pyrans ; analysis ; Reproducibility of Results ; Sensitivity and Specificity