AIM: To study the anti-inflammatory and antipyretic effects of total alkaloids of Aconitum sungpanense Hand-Mazz (TAS). METHODS: The inflammatory models were established by injection different inflammatory agents in mice and rats, and the fever model by the intravenous injection of vaccine of typhoid and paratyphoid in rabbits. RESULTS: TAS ( 0.3 - 0.6 mg?kg -1 ,ip) inhibited the edema of hind paw induced by injection of fresh albumen, and formaldehyde in rats, the ear swelling induced by xylene in mice, and the proliferation of granule induced by injection of agar in rats. TAS lowered the temperature of feverish rabbits. CONCLUSION: TAS shows marked anti-inflammatory effect on both acute and chronic inflammation, and antipyretic effect.

An EPA and DHA enriched fish oil ( containing EPA 0.24 g/L, DHA 0.47g/L ) was administered by gastric intubation at the dose of O.2ml/100g wt for a period of one month in the hyperlipoprotein-emia rats caused by high lipid and cholesterol feeding. The administration of fish oil resulted in reduction in TG ( Triglyceride ) ; TC ( Total Cholesterol ) and VLDL-C + LDL-C levels in serum. Levels of HDL2-C and ratio of HDL2/HDL3 were elevated although there was no significant change in level of HDL-C. The study suggests that oral administration of EPA and DHA enriched fish oil might reduce the developoment of atherosclerosis.

Objective To identify the effect of using modified 99 type China hemp service shoes and socks on preventing servicemen from skin superficial fungal infection during the drill.Methods A double-blinded control study was carried on in 2 months test with 16 testees who wore the modified 99 type China hemp service shoes and socks.Every testee was dispensed 1 pair of shoes and 3 pairs of socks.The left socks were produced in different material and way from the right one in each pair.Clinical examination of feet skin primary lesions and fungal test on each individual testee were done at the beginning of this research,as well as in the middle and the end.Results The clinical symptoms of 16 testees' feet skin were obviously relived during the 2 months test.4 of 16 testees claimed that there were more obviously relieving of feet symptoms on left than right.8 of 16 testees which were positive of fungal test at the beginning of the research claimed that their feet symptoms were lessened,and 2 of the above 8 were turned to negative of fungal test after 8 weeks,however the other 6 were positive yet.And the fungi culture was done on these 6 above testees who were still positive on fungal test.2 cases were Trichophyyon gypseum,while other 4 cases were Trichophyyon rubrum.Conclusion The modified 99 type China hemp service shoes and socks can relieve the clinical symptoms and prevent fungal infection that occurs during the drill.

Objective To describe the imaging appearances of mesenteric cavernous hemolymphangioma.Methods The ultrasonography(USG) and CT findings of 5 patients with mesenteric cavernous hemolymphangioma confirmed by operation and pathology were analyzed retrospectively.Results The tumors were reticulate hypoechoic masses on USG,the insides of them were of abundant red or blue blood flows signal on colour Doppler flow imaging(CDFI).On CT,the masses appeared as heterogeneous density with irregular margins and multiple round-like iso-or low dense cystoid foci with asymmetric thickness walls around the lesions.Conclusion The application of CT combined with USG may improve the diagnostic accuracy of mesenteric cavernous hemolymphangioma.

The fluctuation of medical staff thoughts and hospital rapid action during SARS epidemic, we name it "hospital phenomenon during SARS", has its specific characteristics. We analyzed this phenomenon from the following points: the conflict between panic response and the duty of the profession, the contradiction between the need to control infection and the available conditions, the special following phenomenon post - diagnosis of SARS and the hospital routine activity and SARS prevention and cure. We conclude that at least three fields should be improved, that is to strength education of duty morals, to normalize the medical procedure, and to build the dual system of hospital' s routine run and rapid action, in order to constructing hospital credit ethic.

This article is a part of a systemical study of the Chinese sternum. A total of 191 cases (male 111 cases, female 80 cases) of Chinese adult sternum werc measured. The chief results obtained are as follows:1. The sternal length is 147.6?1.24 mm in male and 137.54?1.30 mm in fcmale.2. The manubrium length of the sternum is 49.42?0.46 mm in male and 48.20?0.66 mm in female. The maximum width of the sternum is 62.96?0.65 mm in male and 59.61?0.71 mm in female. The minimum width of the sternum is 33.71?0.48 mm in male and 31.97?0.34 mm infemale. The thickness of the sternum is 10.19?0.09 mm in male and 9.97?0.16 mm in female.3. Thc length of the body of the sternum is 100.18?1.15 mm in male and 88.20?1.14 mm in female. The maximum width of the body of the sternum is 39.20?0.51 mm in male and 36.98?0.49 mm in female. The maximum thickness of the body of sternum is 12.43?0.22 mm in male and 11.50?0.21 mm in female.4. The length width index of the sternum is 26.66.5. The length width index of the sternal Body is 39.86.

This article is a part of a systematical study of the Chinese sternum. A total of 191 cases (111 males, 80 females) of Chinese adult sternum were measured. The chief results obtained are as follows:1. The sternal length is 147.6?1.24mm in the male and 137.54?1.30mm in the female.2. The manubrium length of the sternum is 49.42?0.46 mm in the male and 48.20?0.66mm in the female. The maximum width of the sternum is 62.96?0.65mm in the male and 59.61?0.71mm in the female. The minimum width of the sternum is 33.71?0.48mm in the male and 31.97?0.34mm in the female. The thickness of the sternum is 10.19?0.09mm in the male and 9.97?0.16mm in the female.3. The length of the body of the sternum is 100.18?1.15 mm in the male and 88.20?1.14 mm in the female. The maximum width of the body of the sternum is 39.20?0.51 mm in the male and 36.98?0.49 mm in the female. The maximum thickness of the body of sternum is 12.43?0.22mm in the male and 11.50?0.21 mm in the female.4. The length-width index of the sternum is 26.66.5. The length-width index of the sternal body is 39.86.6. The width-thickness index of the sternum is 31.00.7. The index of the length of the sternal body and the manubrium is 50.00.8. The index of the length of the sternum and the manubrium is 34.38.9. The index of the width and the length of the manubrium is 80.00.

In order to find the mechanism of superior clunial nerve (SCN) trauma, we dissected and revealed SCN from 12 corpses (24 sides). Combining 100 sides of SCN trauma, we inspected the course of SCN, the relation between SCN and it's neighbour tissues with the situation of SCN when being subjected to force. We found that the following special anatomic characteristics and mechanical elements such as the course of SCN, it's turning angles, the bony fibrous tube at the iliac crest, the posterior layer of the lumbodorsal fascia and SCN neighbour adipose tissue, are the causes of external force inducing SCN trauma. The anatomic revealment is the guidance of SCN trauma treatment with edged needle.

The paper reported an investigation of the pharmacokinetics of SN-38 (7-ethyl-10-hydroxy-camptothecin) in rats and the tissue distribution in mice after injection of irinotecan hydrochloride nanoparticles (CPT-11) via tail veins. An LC-MS/MS method was established to determine the concentrations of SN-38 in whole blood of rats and in different tissues of mice. The pharmacokinetics and tissue distribution of SN-38 were compared after the intravenous injection of CPT-11 NPs and CPT-11 solution. Compared with irinotecan solution, the elimination half-life of SN-38 was prolonged from 2.17 h to 2.67 h after the intravenous injection of CPT-11 NPs, but its AUC had little change. After the injection of CPT-11 NPs in mice, over time, the concentrations of CPT-11-metabolized SN-38 in CPT-11 NPs were significantly higher in the whole blood, colon and lungs than those in CPT-11 solution, followed by in the spleen and liver, but those in the heart and brain had no change. However, the amount of SN-38 in the kidneys was reduced with time. CPT-11 NPs could prolong SN-38's (one of its metabolites) blood circulation time in rats and significantly increased the concentration of CPT-11-metabolized SN-38 in the whole blood, colon and lungs of mice. CPT-11 NPs made SN-38 efficiently target-bind to the colon and lungs of mice.

Objective:To research the clinical effect of abdominal total hysterectomy on the patients with uterine fibroids and the serum vascular endothelial growth factor (VEGF) and interleukin 6 (IL-6),interleukin 8 (IL-8) levels.Methods:106 cases of patients with uterine fibroids from February 2014 to February 2016 were divided into the control group and the research group according to the lottery method,the control group was treated with total abdominal hysterectomy,while the research group was given abdominal total hysterectomy treatment,the operation time,blood loss,anal exhaust time,length of hospital stay,changes of serum VEGF,IL-6,IL-8,Follicle stimulating hormone (FSH),estradiol (E2) levels,resistance to seedling le tube hormone (AMH) before and after the surgery as well as the occurrence of complications were compared between two groups.Results:The operation time,blood loss,length of hospital stay,anal exhaust time of research group were significantly shorter than those of the control group (P＜0.05).Before surgery,the serum levels of VEGF,IL-6,IL-8,FSH,E2,AMH showed no difference between two groups (P＞0.05).After the operation,the serum levels of IL-6,IL-8,E2,AMH of research group were lower than those of the control group (P＜0.05),the serum level of FSH in research group was higher than that of the control group (P＜0.05).The serum level of VEGF showed no difference between the two groups (P＞0.05).The incidence rate of complications in research group was lower than that of the control group (P＜0.05).Conclusion:Abdominal total hysterectomy showed similar effect with the abdominal hysterectomy in the treatment of uterine fibroids patients,but the abdominal full hysterectomy induced less trauma,promoted the recovery of ovarian function after surgery,which might be related to the decrease of serum IL-6,IL-8 and VEGF levels.