Systemic lupus erythematosus is an organ atypical autoimmune disease which must be monitored for long time during treatment course and all the livelong. The variation of disease depends to various factors (inherent factors and also environmental factors). Therefore, treatment with and without medication has got importance equally. Activation indices of the disease will answer properly the question of giving and giving up the medicaments.
Lupus Erythematosus, Systemic ; Therapeutics ; Epidemiology

31 patients of psoriasis were involved in this open, uncontrolled 4 weeks study of dose MTX: 0.3mg/kg/36 hour/week, 29 subjects were men and 2 were women. Their ages ranged from 21 to 65 years old. The mean duration of psoriasis experienced was ranged from 1 to 20 years. The mean PASI score at baseline was 22.73±14.34. After treatment the PASI score was mean decreased 86.89%. MTX was effected early and every form of psoriasis.
Therapeutics ; Psoriasis ; Pharmaceutical Preparations ; Methotrexate

A prospective study was conducted on 33 psoriasis patients treated with methotrexate (MTX) 0.1mg/kg in continuous 5 days at the Dermatological Department of the Army Central hospital from 2000-2004. Results: MTX had high effect in treatment of usual psoriasis (very good: 24.24%; good: 21.21%; relatively good: 45.45%; medium 9.10%); it had early effect (at the first round) and had effect on all kinds of psoriasis: usual type (with the severe level, PASI reduced 64.76%; average 70.99%; light: 94.86%) DDTT type (PASI reduced 73.63%). After methotrexate therapy, 45.45% of patients had a increased rate of SGOT, 39.39% had a increased rate of SGPT; the number of white blood cells decreased in 9.1% of patients, and red blood cells and platelet decreased in 3% of patients . Additionally, the treatment also caused some other symptoms such as fatigue in 10/33 patients (30.3%), anorexia in 13/33 patients (39.40%). The researcher suggested: do not use MTX at daily dose to treat psoriasis.
Psoriasis ; Therapeutics ; Methotrexate

Herpes zoster caused by herpes varicella-zoster virus (VZV). From January to December 2004, 43 patients with herpes zoster were treated by Acyclovir 1000mg/day for 7 days at Demartology Department, Army Hospital No108. In this study, we found good result in 30.23% of patients, moderate result in 67.44%, poor result in 2,33%. Treatment effectiveness related to stage of disease, age when having diagnosis and age of patients.
Herpes Zoster ; Acyclovir ; Therapeutics

Investigated 52 patients with herpes zoster were treated at Dermatology Derpartment, Army Hospital No 108 showed that: Males is triple than females. Most of patients aged more than 50 years (76.92%). Fever: 9.62%, fatigue:19.23%, swell glands: 53.85%, pain:100% (69.23% of patients who aged more than 50 years had pain). Herpes zoster affected to intercostal space in 38.46%, head-face in 23.07%, lumbar-reproduction-thigh in 19.23%, neck-arm in 11.54% and chist-arm in 3.85%. Mild disease group 3.85%, moderate disease group 26.92% and severe disease group 69.23%. Other conditions seen in patients with herpes zoster included hypertension in 21.62%, stomach disease in 13,46%, diabetes in 11.54%, hyperlipidemia in 9.62%, psoriasis in 3.85% and goutte in 1.92%.
Herpes Zoster ; Therapeutics ; Diagnosis ; Epidemiology ; Outpatients

35 patients with Alopecia Areata (18 females, 17 males) were treated at Military hospital N0 108 from March 2002 to March 2005, age from 4 to 58 years old. All patients were treated by HDM alcohol and Chloral salicylic solution 2% in 4 months. The results showed that: after first month of treatment, 77.14% of patients had grew hair root; after 2 months, there was only 8.57% of patients had not yet grew hair root. After 3 months, the rate of grew hair with different levels was 100%, among which 60% had normal grew hair, and after 4 months 82.86% of patients had grew hair as normally, 17.14% had grew hair from 2 cm. Side effects were observed in 10 patients (28.57%) involved erythema 8.57%, itch 14.29% and deciduous skin 5.71%.
Alopecia Areata ; Alcohols ; Therapeutics

Comparison of the efficacy of Acyclovir combined paracetamol, and Acyclovir, Amitriptyline combined paracetamol in the treatment of Herpes Zoster in 60 patients (45 males, 15 females) at Dermatology of Central Military Hospital 108 from March 2004 to March 2005. The subjects were divided into 2 groups. Group 1 (30 patients) used Acyclovir 200mg, 5 tablets/day for 7 days; Amitriptyline 25mg, 1 tablet/day and paracetamol 0.5-2 tablets/day. Group 2 (30 patients) administrated Acyclovir 200mg, 5 tablets/day for 7 days and paracetamol 0.5-2 tablets/day. The results showed that: all of 2 methods had good effects and similar results in overall results and the time to dry vesicle, but decreased pain level of group 1 was better than that of group 2. Amitriptyline had a good relieve pain’s effect in treatment of Herpes Zoster.
Herpes Zoster ; Therapeutics

Comparison of effect of Canida Albicans fungus treatment with oral Sporal in dose of 200 mg/time/day for 3 days and 5 days continuously, and evaluation of side effects of 2 regimens in 24 female patients with vaginal Canida Albicans fungus, treated at Dermatology Department of Central Military Hospital No.108 from 2000-2004. The results: both of continuously Sporal 200 mg/time/day for 3 days and 5 days therapy gained a good results. However, the recurrent rate after 2 months in continuously 3 days regimen was 41.67% (5/12 patients), and there was no case of recurrence in 5 days treatment regimen. Both 2 regimens did not have any side effects. If having indication of treating vaginal Canida Albicans fungus with Sporal, should apply 200mg/time/day for 5 days continuously regimen.
Candida albicans ; Therapeutics

At the Hospital number 108, in the Department of Dermato-Venerology, an investigation was performed on 58 patients with psoriasis at the progressive stage in order to determine the change of peripheri blood globuline and clinical features of the disease. The quantification of globuline showed that IgA and IgG levels decreased but normal level did not still reestablished. The variations of IgM were not significant. Between IgA and IgG levels, there was a positive and closed relation. IgA and IgG level increased early, immediately in the mild level of the disease and in the recessive stage of the disease at three levels, they were also higher than that of the control group; particulally, IgA in severe level did not drop down even when the disease was recessive. IgM levels were not changed in any levels of the severity.
Psoriasis ; Globulins ; Blood