No abstract available.
Dandy-Walker Syndrome*

No abstract available.
Dandy-Walker Syndrome*

No abstract available.
Dandy-Walker Syndrome*

Congenital onychodysplasia of the index fingers (COIF) is a rare disorder characterized by various forms of nail dysplasia which are mainly limited to the index fingers. The aetiology of the disease is still a matter of debate. COIF is characterized by five criteria: congenital occurrence, unilateral or bilateral index finger involvement, variability of nail appearance, possible hereditary involvement, and frequently associated bone abnormalities. We report a case of COIF, which is associated with Dandy-Walker variant.
Dandy-Walker Syndrome* ; Fingers*

No abstract available.
Dandy-Walker Syndrome*

No abstract available.
Adolescent ; Dandy-Walker Syndrome ; Humans

No abstract available.
Dandy-Walker Syndrome* ; Prenatal Diagnosis* ; Trisomy*

No abstract available.
Carotid Artery, Internal* ; Dandy-Walker Syndrome*

Posterior fossa malformations are rare cyst-like pathologies of the central nervous system. Outcomes of patients with these conditions are largely documented in fetal or early childhood studies as most cases are non-compatible with life. Also, different schemes to categorize these occurrences have been proposed. One classification puts forth that the entities are a continuum of pathologies, called the Dandy Walker Complex, wherein Mega Cisterna Magna is the most benign to Dandy Walker Malformation as the most severe form. We report the first case of a patient with a mixed presentation of Mega Cisterna Magna having extracranial manifestations of Dandy Walker Malformation reaching her adult years. The patient is a 26-year-old female who was apparently well until she presented with recurrent headache and seizure episodes of 2-year duration. She had an unremarkable birth and childhood history, apart from learning difficulties in school. In her adult years, she gave birth to an infant with multiple physical anomalies. She has a maternal uncle with abnormal facie and intellectual disability. Physical examination of the patient exhibited a bulging occiput, hypertelorism, down-slanting palpebral fissures, large globular nose, large ear lobules, high arched palate, and clinodactyly. Neurologic examination was unremarkable. Magnetic resonance imaging confirmed Mega Cisterna Magna and was deemed non-surgical. She remained seizure-free during admission as well as on followup, maintained on Phenytoin. The existence of a Dandy-Walker continuum is still debated, as the link among the disease entities are yet to be established using developmental or genetic studies. This case, however, supports the Dandy-Walker Complex classification by demonstrating a rare combination of Mega Cisterna Magna with features of Dandy-Walker Malformation in an adult. This can contribute to disease definition and eventually to the discovery of the pathobiological mechanisms of posterior fossa cysts, and to appropriate diagnosis and management.

A very characteristic congenital anomaly, atresia of the foramina of Luschka and Magendie, the outlet foramina of the fourth ventricle, referred as the Dandy-Walker Cyst by Raimondi and et al. in 1968. Really in 1921, Dandy discussed the clinical diagnosis and treatment of hydrocephalus secondary to occlusion of the foramina of Magendie and Luschka. In 1944, Walker reported a case of congenital atresia of the outlets of the fourth ventricle treated surgically. We are reporting one case of this cyst was surgical intervention and carried autopsy.
Autopsy ; Dandy-Walker Syndrome* ; Diagnosis ; Fourth Ventricle ; Hydrocephalus