1.Research on how to improve the whole-process management of medical devices
China Medical Equipment 2013;(9):68-70,71
Objective: To improve the whole-process management of medical devices in purchase, use and maintenance. Methods: In this paper, we clarify the purchase, use and maintenance requirements of large-scaled medical devices including justification, invitation organization, comprehensive estimation, contract signing protocol, advantage analysis, rational control of availability, efficacy measurement and detection, management at different levels, high-efficacy check-up and scrap procedure to adapt the new challenges during the introduction of more and more advanced, complex and high-tech medical devices. Results:The results being analyzed could be used as important evidence for future purchasing of medical equipment, which was important for scientific and reasonable purchasing and utilizing of medical equipment. Conclusion: Strengthen the management to adapt the new challenges during the introduction of more and more advanced, complex and high-tech medical devices.
2.Systematization and informatization for the management of medical equipment archive
China Medical Equipment 2014;(6):86-88
Objective: To establish the Perfect Systematization and Informatization for the Management of Medical Equipment Archive, so as to ensure the integrity and traceability of each data. Methods: Analysis on Present Situation and the Problems of Medical Equipment Management, Establish Medical Equipment archive Management System from purchasing of medical equipment, Measurement Controls, the Maintenance to Scrap processing the whole-process of medical devices. Results: In this paper, we discussed all kinds of information and archives network information management in the whole-process of medical devices. To clarify the plan, argument, purchase, installation, acceptance, use, quality control, maintenance, transfers and scrap processing, management at different levels. To establish a complete electronic file system is the main direction of medical equipment information management in the future. Conclusion: Realization of the functions on medical equipment archives network information and dynamic management, that can offer necessary for safe treatment,to can also reduce the operation cost of the equipment.
3.Management of hospital first-aid equipment and risk control
China Medical Equipment 2014;(5):85-86,87
Objective:This paper makes analysis of problems of emergency equipment existing in clinical application and their causes and puts forward corresponding measure. Methods:Analysis of emergency medical equipment characteristic and the difference between conventional equipment. Find the first aid equipment management problems and reasons existing in the use, and risk assessment. Results:Hospital first aid equipment has the characteristics of more free time, emergency and risks, widely distributed in each department. By the personnel management, periodic inspection, cleaning and disinfection. Risk assessment shall be conducted by experts, the risk value high priority arrangement first aid equipment maintenance, to expect to minimize risk. Conclusion:First aid equipment management is a systematic and important work, to need department, maintenance personnel, equipment manufacturers and so on various aspects to cooperate with each other, to ensure the normal use of equipment.
4.Detection of peripheral blood T lymphocyte subpopulations among patients positive for both hepatitis B virus surface antigen and surface antibody
Dan CHEN ; Qiu-bo WANG ; Dan-dan SHEN
China Tropical Medicine 2022;22(12):1130-
Abstract: Objective To investigate the frequency of peripheral blood T cells among patients positive for both hepatitis B virus surface antigen (HBsAg) and surface antibody (HBsAb). Methods Thirty six patients with co-existence of HBsAg and HBsAb diagnosed were enrolled as the experimental group, who were admitted by Shanghai tenth people's hospital and Wuxi 9th people's hospital from 2014 to 2020. while 40 patients tested positive for HBsAg and negative for HBsAb served as controls, who were admitted by Wuxi 9th people's hospital. Flow cytometry was used to detect and compare the proportions of peripheral blood CD3+, CD4+ and CD8+ T cells between the experimental and control groups. In addition, the associations of serum HBsAb level with peripheral blood T cell proportions, serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were examined among chronic hepatitis B patients with co-existence of HBsAg and HBsAb using Pearson correlation analysis. Results The median age, gender distribution, mean ALT and AST concentrations, proportion of HBV DNA viral load>103 copies/mL, seroprevalence of HBV E antigen (HBeAg), seroprevalence of HBV E antibody (HBeAb), seroprevalence of HBV core antibody (HBcAb) were comparable between the experimental and control groups, and there were no significant difference in them (P>0.05). There were no significant difference between the experimental and control groups in terms of CD3+ T cell proportion [(71.83±1.50)% vs (72.75±1.47)%; t=0.66, P>0.05], CD4+ T cell proportion [(36.81±1.53)% vs (39.88±1.57)%; t=1.43, P>0.05] and CD8+ T cell proportion [(33.17±2.04)% vs (32.40±1.75)%; t=0.77, P>0.05]. Pearson correlation analysis revealed that the serum HBsAb level did not significantly correlate with peripheral blood CD3+ (r=0.026, P=0.65), CD4+ (r=‒0.08, P=0.16) and CD8+ T cell proportions (r=0.09, P=0.24), CD4+/CD8+ T proportion (r=‒0.005, P=0.35), serum ALT (r=0.04, P=0.56) and AST levels (r=0.002, P=0.69) among chronic hepatitis B patients with co-existence of HBsAg and HBsAb. Conclusions There are no significant differences between HBsAg+/HBsAb+ and HBsAg+/HBsAb- CHB patients in terms of peripheral blood CD3+, CD4+ and CD8+ T cell proportions.
5.Macular thickness changes before and after phacoemulsification by optical coherence tomography
International Eye Science 2015;(7):1214-1216
AlM: To observe the influence of phacoemulsification combined with intraocular lens implantation on retinal thickness changes of macular center fovea using optical coherence tomography ( OCT) in cataract patients.METHODS: Surgical eyes of 60 cases with cataract were as surgery group, the contralateral eye were as controls group. There was no complication before and during the surgery. Macular thickness was examined by OCT preoperatively and 1wk, 1, 3, and 6mo after surgery. The retinal thickness changes of macular center fovea were compared after surgery. The SPSS 17. 0 software was used for statistical analysis. The paired t-test and variance analysis were used in two groups before and after surgery for relevant statistical data analysis (α=0. 05).RESULTS: ln surgery group, the retinal thickness changes of macular center fovea at 1wk, 1, 3mo after treatment had significant differences compared with preoperation (P<0. 05). The retinal thickness changes of macular center fovea at 6mo after treatment had no statistical significance compared with preoperation ( P>0. 05). The retinal thickness changes of macular center fovea was significantly higher than other groups at 1mo after treatment (P<0. 05). The center fovea appeared to be abnormally thickened in 12 eyes, including 10 eyes of single fovea thickening and 2 eyes of cystoid macular edema in 2~4wk following surgery. Eleven eyes of them were resolved till 6mo postoperatively. ln control group, preoperation or after operation for 1wk, 1, 3, and 6mo respectively, P values were without statistical differences ( P > 0. 05 ). There were no statistical significant differences on retinal thickness of macular center fovea between two groups before and 6mo after surgery ( P>0. 05), while there were significant differences at 1wk, 1 and 3mo after surgery (P<0. 05) CONCLUSlON: The retinal thickness changes of macular center fovea increases significantly after phacoemulsification combined with intraocular lens implantation. ln a few of cases appear macular edema, but the majority of patients can be restored, prognosis is good.
6. Establishment and application of paravertebral muscle endurance and left-right symmetry measurement indexes and methods in teenagers
Chinese Journal of Tissue Engineering Research 2020;24(14):2197-2204
BACKGROUND: Surface electromyography has Indicated that non-specific chronic low back pain patients have Inconsistent changes in the motion of erector spinae muscles on both sides of the lumbar spine. Existing physical fitness evaluation focuses on the evaluation of the overall strength of the waist, whereas there is no report on the evaluation methods and indicators of paravertebral muscle in teenagers. OBJECTIVE: To establish methods and indicators for assessing teenagers' paravertebral muscle endurance and left-right symmetry, and to preliminarily formulate evaluation criteria. METHODS: Two hundred students, aged 13-18 years, were randomly selected In a middle school of Beijing, half male and half female. There were 100 junior high school students and 100 high school students. All the subjects did Biering-Sorensen (B-S) exercise to maintain Isometric contraction of paravertebral muscles, and surface electromyography was then used to record the electromyography of bilateral erector spine muscles (ES) of L3-L4 and multifidus muscles (MF) of L5-S<|. Measurement was terminated when the upper body could not maintain the horizontal posture or was still below the horizontal position after three reminders. The indexes were screened and the evaluation indexes were established. The evaluation criteria of paravertebral muscle endurance and left-right symmetry of each age group were determined by the dispersion method. The study protocol was In line with the ethics requirements of Beijing Sport University. Subjects and their guardians were fully Informed of the study process. RESULTS AND CONCLUSION: According to the anatomic posture analysis and muscle mobilization ratio test, the left/right erector spine muscle (LES/RES) and left/right multifidus muscle (LWF/RMF) in B-S action were confirmed to be the prime muscle. Mean power frequency (MPF) decreased linearly with time, and the correlation coefficient was R < -0. 97 (P < 0. 01). In terms of repeatability measurement, MPF slope (slopeMPF) difference test was defined as P > 0. 05, and correlation coefficient within the group was ICC > 0. 80 (P < 0. 01), indicating a good repeatability. Fitting composite Index, the Index v=slopeMPF (LES+RES+LMF+RMF)/4 was used to evaluate teenagers' paravertebral muscular endurance, and u=slopeMPF (LES-RES)/slopeMPF (LES+RES)+slopeMPF (LMF-RMF)/slopeMPF (LMF+RMF) was to evaluate the left-right symmetry. The evaluation results revealed that the paravertebral muscle endurance of high school students of the same sex was Increased In relative to junior high school students (P < 0. 01). There were significant differences in paravertebral muscle endurance between male and female students In high school. The teenagers' paravertebral muscle endurance and symmetry showed normal distribution, and could be graded by deviation method. In this study, the Indexes and methods for evaluating paravertebral muscle endurance and left-right symmetry were preliminarily established, and the criteria for evaluating juvenile paravertebral muscle endurance and left-right symmetry were preliminarily established by deviation method.
8.Efficacy of progesterone combined with Tiaojinghuoxue tablets treatment of amenorrhea induced by antipsychotic drug s
The Journal of Practical Medicine 2014;(24):4018-4020
Objective To explore the clinical efficacy and safety of progesterone combined with Tiaojinghuoxue tablets in treating amenorrhea induced by antipsychotic drugs. Methods Total 100 patients were randomly divided into treatment group treated by progesterone combined with Tiaojinghuoxue tablets and progesterone group. The index including prolactin (PRL), luteinizing hormone (LH), estradiol (E2), endometrial thickness were measured before and after treatment in both groups . Also the clinical efficacy of the twogroups were compared. Results PRL, LH, E2, endometrial thickness and the recovery of menstrual flow rates in combination group were all better than the progesterone group, (P<0.05 or P<0.01). Cure rate in the combined group was 54.00%and the control group was 74.00%(P<0.05). Total effective rate of combined group was 90.00%and the control group was 80.00%(P>0.05). The rate of adverse reactions in combined group was 40.00%, less than 22.00%in progesterone group, (P<0.05). Conclusion The efficacy of progesterone combined withTiaojinghuoxue tablets is better than single progesterone treatment and have fewer adverse reactions in therpy antipsychotics drug induced amenorrhea.
9.Research progress of relationship between inflammation anti heart failure
Journal of Shanghai Jiaotong University(Medical Science) 2009;29(6):649-653
Accumulating studies have proved that systemic inflammation is one of the important pathophysiologic mechanisms of heart failure. This article focuses on the sources of inflammation mediators and the causes of inflammation activation in heart failure including hemodynamic changes and oxidative stress, Toll-like receptors, microbial antigens and microorganisms, endotoxin hypothesis and neurohormonal activation. Furthermore, the effects of inflammation mediators such as cytokines and chemokines on heart failure are introduced. All lead to the conclusion that heart failure is a process with complex inflammation.
10.Recent advances in studies on vascular progenitor cells.
Qiu-rong RUAN ; Yan LI ; Dan YAN
Chinese Journal of Pathology 2009;38(8):507-510
Animals
;
Cell Differentiation
;
Cell Movement
;
Chemokine CXCL12
;
metabolism
;
Endothelial Cells
;
pathology
;
physiology
;
Humans
;
Muscle, Smooth, Vascular
;
pathology
;
physiology
;
Receptors, CXCR4
;
metabolism
;
Stem Cells
;
metabolism
;
pathology
;
physiology
;
Vascular Diseases
;
metabolism
;
pathology
;
physiopathology