The paper discusses the necessity and the feasibility of co - construction and sharing of collection resources among medical university and local hospital libraries, proposes concrete measures of its implementing, including cultivating overall situation awareness, strengthening resources construction and highlighting the characteristics of collections and implementing unified library card.

Experiments were performed on 29 healthy mongrel dogs with average body weight of 13?2.2kg. The animals were randomly divided into three groups:(1) nine dogs in the hemorrhagic shock group(HS); (2) tendogs in the panaxadiol saponin pretreatement group (HSG), which were intravenously injected with 25mg panaxadiol saponin 1 h before bleeding; (3) In the dexamethasone pretreatment group, othet ten dogs were intramuscularly injected with 1 mg/kg body wt of dexamethasone 1 h before bleeding. The mean arterial pressure of 5.3 kPa was kept during experimental period. The morphological changes of platelet were observed with scanning electromicroscope. The results showed that the platelet damage was much lighter in HSP and HSD gnoups than that of the HS group. The seum 5-HT content of HS group gradually increased hemorrhage with time delay. In the HSG group,the 5-HT level was increased from 1 and 3 h after bleeding,then it was decreased at 4 and 5 h. In the HSD group 5-HT level didn′t show any change from prebleeding to postbleeding. However, in the HS group 5-HIAA concentration increased significantly from 3rd to 5th hour after bleeding in the HS group,but was not in the HSG and HSD groups. These findings suggest that the panaxadiol saponins and dexamethsone can effecti vely inhibit the increasing of 5-HT and 5-HIAA levels in the themorrhagic shock.

The lumbar intervertebral disc is a disc-shaped fibrocartilaginous structure located between the vertebral bodies and acts as an important anatomical structure in the spine for stability. The spinal stability system consists of three subsystems: passive subsystem, active subsystem, and neural control subsystem. Lumbar intervertebral disc degeneration (IVDD), the leading cause of low back pain, induces pathological changes in other tissues of the three subsystems and interacts to degrade spinal stability. IVDD is commonly accompanied by degeneration of facet joint and ligament, Modic change, decreased vertebral blood flow, increased paraspinal muscle fat infiltration, reduced axial tension injury of the nerve, et al. Magnetic resonance imaging (MRI) is the preferred imaging modality for assessing spinal stability. Conventional MRI could completely demonstrate the morphological changes of the three subsystems in IVDD patients, and functional MRI could quantitatively evaluate the degree of pathophysiological change. We summarized the morphological and functional changes of MRI in lumbar intervertebral disc, facet joint, ligament, vertebral body, paraspinal muscle, and nerve of patients with IVDD, and then analysed the changes in spinal stability caused by IVDD, aiming to provide more imaging information for improving diagnosis accuracy and developing appropriate management of patients with low back pain.

Mechanisms of UV-B-induced apoptotic regulation in yeast Saccharomyces cerevisiae were studied. The results showed that UV-B irradiation indeed inhibited the growth of yeast cells as well as induced extensive apoptosis during 96 h experiment period. However, survival of 96 h irradiated cells remained 10% while most control cells finally dead after re-growth under UV-B irradiation for 12 d. And by exposed to 0.01 mol/L or 0.1 mol/L H2O2 for 30 min, survival rate of 24 h irradiated cells were 3.0-fold or 3.2-fold than control, respectively. By to heat shock for 30 min or 60 min, survival rate of 24 h irradiated cells were 3.5-fold or 9.0-fold than control, respectively.

In recent years, there is much debate on how much cholesterol should be taken in with diet. This article reviews the dietary guidelines, recommendations, and strategies of some national and international organizations since the mid-20th century. The dietary cholesterol was systematically combed and interpreted on its intake for the general population and special population. We would like to help the professionals and public better understand the meaning of the guidelines, to eliminate the misunderstanding of dietary cholesterol and to establish the correct concept of healthy eating pattern.

Child ; Contraindications ; Humans ; Kidney Diseases ; immunology ; Risk Factors ; Vaccination

Acupuncture Points ; Acupuncture Therapy ; instrumentation ; Adult ; Aged ; Arrhythmias, Cardiac ; therapy ; Female ; Humans ; Male ; Middle Aged ; Needles

Objective:To establish a rat hyperparathyroidism model secondary to chronic renal failure,so as to lay a foundation for studying the mechanism and treatment of secondary hyperparathyroidism.Methods: Thiry-six male Sprague-Dawley rats,weighing 200-250 g,were randomly divided into 6 groups: 5/6 nephrectomy plus high phosphorus food group(STNx + HP),5/6 nephrectomy plus low phosphorus food group(STNx + LP),5/6 nephrectomy plus normal phosphorus food group(STNx + NP),sham operation plus high phosphorus food group(Sham + HP),sham operation plus low phosphorus food group(Sham + LP),and sham operation plus normal phosphorus food group(Sham + NP).Nephrectomy was performed in 2 steps.Serum phosphorus levels(P) and iPTH levels were detected at day 7 pre-operation and day 7,14,and 21 after the second operation.The kidneys,thyroid glands and parathyroid glands complex underwent pathological analysis 4 weeks after operation.Results: Five patients survived in STNx+NP group,4 in STNx+LP group and 4 in STNx+HP group postoperatively.No death occurred in sham operated groups.Serum phosphorus levels of nephrectomy groups at different time points after operation were higher than those before operation and those of sham operation groups(P

Objective To investigate the effect of transverse incision surgery for epicanthoplasty with double eyelid fold reconstruction. Design Retrospective case series. Participants 103 patients with epicanthus. Method Transverse incision was applied for epicanthoplasty in all patients, and incorporated with double eyelid fold reconstruction. Patients were followed up 3-6 months. Main Outcome Measures Size of lacrimal caruncle, length of palpebral fissure, inner canthic diameter and scarring degree. Results Lacrimal caruncle was revealed 3/4 merous in 21 cases, 2/3 merous in 56 cases, 1/2 merous in 8 cases. Extent of palpebral fissure was 30-31mm in 5 cases, 28-29 mm in 69 cases, 26-27 mm in 11 cases. Inner canthic diameter was 32-33mm in 61 cases, 30-31 mm in 23 cases, 29 mm in 1 case. The scarring was little in 56 cases, obviously in 29 cases. Epicanthus relapsed in 2 cases. 16 cases lost follow-up. Conclusion Transverse incision surgery for epicanthoplasty with double eyelid fold reconstruction has less tissue damage and minimal scarring produced at the medial cantha. It is a simple and reliable surgical approach for correction of epicanthus.

[Objective]To compare the expression of calcitonin gene-related peptide(CGRP) receptor in rat bone marrow mesenchymal stem cells(rBMSCs) and the induced osteoblasts.[Method]The rBMSCs were isolated using whole bone marrow adherence method,and classified into osteoblast-induced group and non-induced group.In the different periods of culturing(1,2,and 3 weeks),identification of osteoblasts was performed by immunohistochemistry and reverse transcriptase-polymerase chain reaction(RT-PCR),and expression of the CGRP receptor was detected by Western Blot and RT-PCR.[Result]RT-PCR test demonstrated that osteoblast-induced group had a higher expression of CGRP receptor than non-induced group at the same time point,expression of CGRP receptor was increased in a time-dependent manner in the osteoblast-induced groups.Western Blot test demonstrated that osteoblast-induced group had a higher expression of CGRP receptor than non-induced group at the same time point.Expression of CGRP receptor was increased in a time-dependent manner in osteoblast-induced groups.[Conclusion]According to the mRNA test and protein test,it is suggested that CGRP receptor exists in the rBMSCs.CGRP receptor expression increased in the progress of osteogenic differentiation.