The purpose of the study is to compare and analyze the accuracy of digital images obtained from impression and stone model with model scanner and to find out clinical effectiveness. A mandibular left first molar composite resin tooth was made for abutment. Digital models were obtained with a same model scanner(Ceramill Map 400, Amann Girrbach, Austria); (1) Fabricated resin model was scanned(Group C). (2) 10 impressions were taken with putty and polyvinyl siloxane, then were scanned (Group I). (3) Type IV stone was poured in each impressions made in step(2) and 10 stone models were scanned(Group S). 3 dimensional super-impositional program (Geomagic control X, 3D Systems, USA) was used to analyze the STL files. Stone model scan(Group S) showed lower deviation than impression scan(Group I) compared to the control group(P < 0.001). Both Group I and Group S showed signs of expansion in the occlusion surface and margin surface while showing contraction in the axial surface. The deviations were smaller in order of occlusal plane, horizontal plane of margin and axial plane. Within the limited boundary of this study, the digital model obtained from stone model scan showed smaller deviation than the digital model obtained from impression scan.
Dental Occlusion ; Molar ; Polyvinyls ; Siloxanes ; Tooth ; Treatment Outcome

Nasal extranodal natural killer/T cell (NK/T cell) lymphoma is more common in East Asia than in the United States, comprising up to 7-10% of all non-Hodgkin's lymphoma. Early nasal symptoms are nonspecific and similar to chronic rhinosinusitis, such as nasal obstruction and nasal bleeding. With disease progression, inflammation and necrosis of the mucosa increase, hindering pathologic diagnosis. We experienced a case of nasal extranodal NK/T cell lymphoma in a 58-year-old woman who presented with recurrent periorbital swelling.
Cellulitis* ; Dacryocystitis* ; Diagnosis ; Disease Progression ; Epistaxis ; Far East ; Female ; Humans ; Inflammation ; Lymphoma* ; Lymphoma, Non-Hodgkin ; Middle Aged ; Mucous Membrane ; Nasal Obstruction ; Necrosis ; United States

Pregnancy rhinitis is a relatively common condition. It is characterized by the presence of nasal symptoms, especially nasal congestion, not present prior to pregnancy, but typically present during the last 6 or more weeks of pregnancy, without other signs of respiratory tract infection or any known allergic causes, and disappearing completely within 2 weeks after delivery. Nasal saline irrigation, intranasal steroid spray, and oral antihistamines are usually recommended as the first line of treatment for rhinitis. However, most pregnant women refuse medical treatment for pregnancy rhinitis because of the fear of teratogenicity. Severe pregnancy rhinitis increases the risk of snoring, which has been suggested as having adverse effects on the fetus. In cases where the patients are unable to control their symptoms, pregnancy rhinitis can negatively affect the quality of life (QOL) as well as the pregnancy outcome. Therefore, special caution is required for determining the appropriate diagnosis and treatment modalities for pregnancy rhinitis. Here, we report for the first time, the successful treatment of pregnancy rhinitis that was unresponsive to conservative management and medical therapy by using microdebrider-assisted inferior turbinoplasty at the final stages of pregnancy, along with a review of the relevant literature.
Diagnosis ; Estrogens, Conjugated (USP) ; Female ; Fetus ; Histamine Antagonists ; Humans ; Pregnancy Outcome ; Pregnancy* ; Pregnant Women ; Quality of Life ; Respiratory Tract Infections ; Rhinitis* ; Snoring

We report a case of pityriasis versicolor atrophicans in a 20-year-old woman who presented with chronic multiple brownish atrophic macules and patches on chest and back. The lesions had developed six years ago and the patient had used topical medication including steroid ointments for the last two years prior to visiting our clinic. KOH examination was positive, so skin biopsy was performed and the diagnosis of pityriasis versicolor atrophicans was made. Since our patient had applied topical steroids for some time, it was difficult to rule out steroid-induced atrophy in a common tinea versicolor. Also, differential diagnosis was performed with respect to other skin diseases manifesting with cutaneous atrophy including anetoderma.
Anetoderma ; Atrophy ; Biopsy ; Diagnosis, Differential ; Female ; Humans ; Ointments ; Pityriasis ; Skin ; Skin Diseases ; Steroids ; Thorax ; Tinea Versicolor ; Young Adult

No abstract available.
Leiomyosarcoma* ; Neoplasm Metastasis* ; Scalp* ; Skin

No abstract available.
Multiple Myeloma* ; Bortezomib

Osteoporosis is a metabolic bone disease that is characterized by low bone mass resulting from an increase in bone resorption relative to bone formation. The most current therapies for osteoporosis have focused on inhibiting bone resorption by osteoclasts. The purpose of this study is to develop new anabolic agents for treatment of osteoporosis that have fewer risks compared to conventional therapies. We searched the natural products that were derived from the traditional Asian medicines which have been used for treatment of bone related diseases. Icaritin is a flavonoid glycoside derived from the herb Epimedium which has beneficial effects on bone formation. To determine the effect of icaritin on bone formation, we examined the effect of icaritin on MC3T3-E1 cell proliferation and differentiation. For determining the effects of icaritin on proliferation, we performed the MTT assay using MC3T3-E1 cells. To evaluate whether icaritin could promote the osteogenic differentiation of MC3T3-E1 cells, alkaline phosphatase (ALP) activity and mRNA expressions of Runx2, osteocalcin (OCN), RANKL, and osteoprotegerin (OPG) were determined. Icaritin increased MC3T3-E1 cell proliferation. Icaritin increased the ALP activity of MC3T3-E1 cells on 72 hour culture in osteogenic media. mRNA expression of Runx2 was increased after 24 hour culture with icaritin. mRNA expression of osteocalcin was increased after 72 hour culture with icaritin. In addition, icaritin increased the mRNA expressions of OPG and RANKL. However, icaritin increased the mRNA expression of OPG much more than that of RANKL, and then, it increased the OPG/RANKL ratio. These results suggest that icaritin promotes osteogenic differentiation of osteoblasts and decreases osteoclast formation regulated by osteoblasts.
Alkaline Phosphatase ; Anabolic Agents ; Asian Continental Ancestry Group ; Biological Products ; Bone Diseases, Metabolic ; Bone Resorption ; Cell Proliferation ; Epimedium* ; Humans ; Osteoblasts ; Osteocalcin ; Osteoclasts ; Osteogenesis ; Osteoporosis ; Osteoprotegerin ; RNA, Messenger

Kerion celsi is an inflammatory dermatophytosis of the scalp which is characterized by an acute suppurative process caused mainly by zoophilic dermatophytes. Systemic corticosteroid can be added to systemic antifungal treatment for reducing scarring alopecia, but focal cicatricial changes are unavoidable in a severe case. We report a case of kerion celsi caused by T. mentagrophytes, zoophilic dermatophyte, in a 7-year-old girl. This patient had localized painful erythematous crusted plaques with multiple inflammatory pustules on the scalp. Although she was initially treated with antifungal agent and systemic corticosteroid, focal scarring alopecia occurred eventually. Eventually, the cicatricial change was corrected surgically after two and a half years in spite of timely and appropriate treatment.
Alopecia ; Arthrodermataceae ; Child ; Cicatrix ; Humans ; Scalp ; Tinea ; Tinea Capitis

Schwannoma is slowly-growing, benign tumor that originates from the schwann cell and is rarely found in the external auditory canal (EAC). In this article, we describe a 30-year-old female patient with 12x7x4 mm EAC schwannoma located between the helical crura and tragus of the left ear. The schwannoma was easily removed by local excision. We discuss the differential diagnosis, clinical and histologic features, and treatment of EAC schwannoma.
Adult ; Diagnosis, Differential ; Ear ; Ear Canal* ; Female ; Humans ; Neurilemmoma*

This study sought to analyze the need for nutritional education to enhance the selection of desirable foods by adolescents. A total of 480 high school students in Incheon were surveyed and their responses were analyzed for the recognition of nutrition labeling and their consumption of processed foods and snacks. Almost all the students (93.1%) recognized nutrition labeling, but 54.6% rarely checked the nutrition labeling. The nutrients recognized as important in the nutrition label of processed foods were total fat/saturated fat/trans fat (3.75 out of 5), calories (3.68), and sodium (3.67) in that order. The recognition of the importance of calories was significantly higher in female students compared to male students (3.78 vs. 3.58, P＜0.05). The information identified as important were the date of manufacture and expiration (4.21 out of 5), price (4.14), and the nutrition label (3.15). The preference for processed foods was highest in the order of beverages (4.03 out of 5), noodles (4.02), and frozen desserts (3.97), and the preference of females for processed foods was significantly higher than males (P＜0.001). The time when snacks were most frequently consumed were before going to the academy (21.0%), after school (19.4%), and after attending private institutes (15.0%). The main reasons for using processed foods as snacks were taste (44.4%), ‘no time to eat a meal’ (26.4%), and low price (17.7%). In conclusion, while students mostly recognized nutrition labeling, the actual usage rate was low, and snacks were selected and consumed instead of meals for reasons such as attending academic institutes after school. Thus, to encourage the choice of proper processed foods and snacks for adolescents, practical nutrition education using nutrition labeling is needed.