150 slides of vaginal sample of married women aged 16-49 years old at 8 village of Ha Tay province were investigated. In 51.6% of subjects, there is not pathological manifestation in 48.3% - inflammative damages, then 38.6% with chronical manifestation and 12.6% with acute PaP1 account for 62.6%, PaP2: 24.5% and PaP3: 0.13%. There is not any cancerous damage. Hygiene condition, obstetrical history and venerological diseases were factors related to inflammative state and cervix cell morphology change
Women ; epidemiology ; Cervix Uteri ; cells

From 1996 to 2000, 73 samples of renal biopsy in patients >16 years old with glomerulonephritis and nephrotic syndrome were study on light microscopy. Results: the rate of minimal change glomerulopathy was highest (72.6%), then was the rate of diffuse mesangial proliferative glomerulonephritis (20.6%). The rates of focal segmental glomerulonephritis, membranous proliferative glomerulonephritis, and membranous glomerulonephritis in this study were lower than the other studies. The changes in minimal change glomerulopathy are glomerular basement membrane thickened irregularly, widening and effacement of the visceral epithelial cell foot processes
Glomerulonephritis, Membranous ; Nephrotic Syndrome ; Patients

Acquired Immunodeficiency Syndrome ; prevention & control ; therapy ; China ; Health Policy ; Humans

China ; Humans ; Severe Acute Respiratory Syndrome ; prevention & control

China ; Humans ; Respiration, Artificial ; Severe Acute Respiratory Syndrome ; complications ; diagnosis ; therapy

China ; Communicable Disease Control ; Humans ; Public Health

Papers on reading population in domestic library and information field from 2002 to 2012 were retrieved.Its status quo, academic achievements and inadequacies were analyzed by bibliometrics and suggestions were put for-ward for reading population, such as further dividing its research subjects, strengthening its innovative research, and establishing its assessment system.

Clouston syndrome,also named hidrotic ectodermal dysplasia,is an autosomal dominant genetic disease.It is characterized by hypotrichosis,nail dystrophy and palmoplantar hyperkeratosis.It is caused by mutations in the GJB6 gene.Up to date,there are four GJB6 missense mutations that can cause Clouston syndrome:G1 1R,A88V,V37E and D50N.This article reviews the progress of gene diagnosis and pathogenic mechanism of Clouston syndrome,which can contribute to etiological diagnosis,genetic counseling,intervention as well as treatment.

Purpose To detect the expression of Nek2, Plk1 and Cdk1 in gastric carcinoma and to explore their correlation with clini-copathological factors. Methods We used immunohistochemistry to detect the protein expression of Nek2, Plk1 and Cdk1 in 80 cases of gastric carcinoma. Results The positive rates of Nek2, Plk1 and Cdk1 expressions in 80 cases of gastric carcinoma were 64%, 79% and 85% respectively. While the positive rates of Nek2, Plk1 and Cdk1 expressions in 20 cases normal gastric tissue were 15%, 10% and 20% respectively,with statistical significance (P<0. 01). There were significant associations between Nek2 expression and differentiation of gastric cancer, invasion depth, lymph node metastasis and TNM stage (P<0. 05). There were no significant associa-tions between Nek2 expression and age, gender and tumor size (P>0. 05). The expression of Plk1 and Cdk1 had a correlation with tumor size, differentiation of gastric cancer, invasion depth, lymph node metastasis and TNM stage (P<0. 05). There were no signifi-cant associations between Plk1 and Cdk1 expressions and age and tumor size (P>0. 05). There were significant associations between Nek2 and Plk1, Plk1 and Cdk1, Nek2 and Cdk1 expression (P <0. 01). Conclusions Abnormal expression of Nek2, Plk1 and Cdk1 might be one of the mechanisms of tumorigenesis, especially of abnormal tumour proliferation. They may represent new potential targets for therapeutic intervention.

The advances in domestic knowledge service ability were outlined from the aspects of its concept, constitutional elements, construction and assessment based on an analysis of papers on knowledge service ability covered in CNKI.The related problemsand certain aspects that need to be further studied were pointed out.