The solubility of paracetamol in water is very low. In the manufacturing process of paracetamol tablets, designing the formula and selecting the characteristics of semi final product (such as flow rate, apparent density, granules size and moisture content) greatly affect the finished product's quality (such as hardness, uniformity of weight, dissolution rate of the tablets). The purpose of our research is finding out the optimal criteria to ensure good in vitro bioavailability for paracetamol tablets.
Pancreatitis ; Infant