1.X-linked agammaglobulinemia.
Dal Sik KIM ; Mi Yae YOON ; Hye Soo LEE
Korean Journal of Clinical Pathology 1991;11(3):545-548
No abstract available.
Agammaglobulinemia*
2.In vitro platelet assessment of the stored CPDA-1 platelet concentrates.
Kan Hee HAN ; Jang Soo SUN ; Nam Kyung KIM ; Jay Sik KIM ; Dal Hyo SONG
Korean Journal of Blood Transfusion 1992;3(2):143-150
No abstract available.
Blood Platelets*
3.Value of modified foley catheter method in the removal of blunt esophageal foreign bodies.
Kyung In KIM ; Yoo Mi CHA ; Heon HAN ; Dal Mo YANG ; Hyung Sik KIM ; Young Seok LEE
Journal of the Korean Radiological Society 1993;29(4):844-848
Removal of blunt esophageal foreign bodies using Foley catheter under a fluoroscopic guidance is a well-recognized procedure. However, since this procedure is rather cumbersome and uncomfortable to the patient, the authors tried to find an easier and more convenient modified technique. For 10 patients with esophageal foreign body, we tried the method to the patients who is lying in the right lateral decubitus position and 3 assistants hold head. arms, trunk and legs of the patients without tilting the table and without using immobilizer. Foley catheter is inserted through nostril, nasal cavity and pharynx to esophagus. In order to identify the Foley catheter in esophagus, 0.025 inch short wire was inserted in the Foley catheter. The balloon of a Foley catheter was inflated by 10cc of air, and the syringe was kept attached to the Foley catheter during the procedure. After passage of the foreign body through the upper esophageal sphincter, the balloon was deflated immediately and the foreign body was removed through the mouth. We successfully removed in removing all the blunt esophageal foreign body with ease. This modified method is also fast, safe and efficient.
Arm
;
Catheters*
;
Deception
;
Esophageal Sphincter, Upper
;
Esophagus
;
Foreign Bodies*
;
Head
;
Humans
;
Leg
;
Methods*
;
Mouth
;
Nasal Cavity
;
Pharynx
;
Syringes
4.Diagnostic value of serum Troponin T measurements using EIA method in Acute Myocardial Infarction.
Yoon Jeong KIM ; Dal Sik KIM ; Hye Soo LEE ; Sam Im CHOI
Korean Journal of Clinical Pathology 1997;17(4):553-559
BACKGROUND: Cardiac troponin T (cTnT) is a new serological marker for use as a diagnostic toots for acute myocardial infarction (AMI). This study was designed to evaluate tee diagnostic efficiency of troponin T in AMI. METHODS: We determined the reference range of troponin T in 20 healthy adults without previous cardiovascular diseases and chest pain. We evaluated troponin-T, CK, LD, AST and CK-MB in serum of 13 AMI and 5 angina pectoris patients. The patients were arrived at the hospital within 3 hours after onset of (most recent) acute symptoms. Samples were drawn individually at the times of 0, 1, 3, 7, 18 and 24 hours after admission and continued at 6-h intervals for 2 days and 24-h intervals fort 2 weeks. Troponin T was determined by an enzyme-linked immuno-sorbent assay (one step sandwich assay) on an ES-300 analyzer. RESULTS: We found that serum troponin-T concentrations in healthy control adults were below 0.07microgram/L. The peak level of troponin-T concentration of patients with AMI was 22.0microgram/L, mean value, at 7 hours after admission and showed 110 times its discrimination limit value (0.2microgram/L). CK-MB value was normalized within 3 days after admission, but cTnT value remained high above its discrimination limit value until 2 weeks after admission during this study. CONCLUSIONS: The data indicate that the measurement of serum cTnT improves efficiency of serological testings of AMI as compared with conventionally used cardiac enzymes.
Adult
;
Angina Pectoris
;
Cardiovascular Diseases
;
Chest Pain
;
Discrimination (Psychology)
;
Humans
;
Myocardial Infarction*
;
Reference Values
;
Serologic Tests
;
Troponin T*
;
Troponin*
5.Gastrointestinal Adenomatous Polyposis Associated with Small Cell Neuroendocrine Carcinoma of the Rectosigmoid: A case report.
Wan Seop KIM ; Eun Kyung HONG ; Kang Sik KIM ; Kwang Soo LEE ; Jung Dal LEE
Korean Journal of Pathology 1996;30(11):1040-1044
In adenomatous polyposis coli there are many colonic and extracolonic manifestations, and various combinations of these induce different clinical presentations and syndromes. We experienced a unique case of adenomatous polyposis of the large intestine and stomach in a 39-year-old man. In the colon, small cell neuroendocrine carcinoma rather than adenocarcinoma had developed, which did not contain adenomatous or carcinomatous foci. The adenomatous polyps in the colon were all small and sessile with no cancerous or precancerous change two years after the resection of the symptomatic gastric adenomas, even though the gastric adenomas were larger and showed dysplastic change. We think this case is another variant of adenomatous polyposis syndrome.
Adenocarcinoma
;
Adenoma
6.A Case of Thelazia callipaeda Isolated from Human Conjunctival Sac.
Hyun LIM ; Dal Sik KIM ; Hye Soo LEE ; Sam Im CHOI
Korean Journal of Clinical Microbiology 1999;2(2):207-211
Thelazia callipaeda is a slender, long, and cylindrical nematode which parasitizes in the conjunctival sac of human and causes conjunctivitis. The animals such as the dog, rabbit, horse, deer, and cow were revealed as its reservoir and some species of the fly suspected as its vector. We experienced a case of T. callipaeda isolated from human conjunctival sac of a 41-year old man who lived in Wanju-gun, Chonbuk province and raised the dogs. He complained of an irritation, itching and foreign body sensation on his right eye and the two worms were picked out of his right eye by forceps from conjunctival sac. General features of the worms were ivory colored and slender. Two worms were 15.2mm and 15.8mm in length and both have less than 1.0mm in maximum width. Microscopically, both of the worms were female. The vulva opening of the worms located anterior to esophago-intestinal junction. The uterus filled with the eggs an6 larvae encysted with oval membrane. The buccal cavity in head portion was tetrazoid and connected with well-developed esophagus. At the tails of the worms, anus and papillae were observed. Characteristic compact cuticular transverse striations were identified on the whole body surface.
Adult
;
Anal Canal
;
Animals
;
Conjunctivitis
;
Deer
;
Diptera
;
Dogs
;
Eggs
;
Esophagus
;
Female
;
Foreign Bodies
;
Head
;
Horses
;
Humans*
;
Jeollabuk-do
;
Larva
;
Membranes
;
Ovum
;
Pruritus
;
Sensation
;
Surgical Instruments
;
Tail
;
Thelazioidea*
;
Uterus
;
Vulva
7.A Case of Lactate Dehydrogenase-IgGk, lambda Complex in Angioimmunoblastic Lymphadenopathy with Dysproteinemia.
Yong Kohn CHO ; Byeong Moon CHOI ; Dal Sik KIM ; Hye Soo LEE ; Sam Im CHOI
Korean Journal of Clinical Pathology 1997;17(1):65-70
There are various complex formations between immunoglobulin and serum enzymes in the body. Of these, LD-Immunoglobulin complex is most common. It has reported that LD-IgG or LD-IgA complex existed in the serum of healthy person or many patients who have various clinical disorders. The clinical significance of complexes is not known, but it results in the increase of total LD activity and interference to the LD isoenzyme electrophoresis interpretation due to its anomalous pattern. We have reported a case of LD-Immunoglobulin complex in AILD(Angioimmunoblastic lymphadenopathy with dysproteinemia) with reference. The patient was admitted with fever, chills and cervical LN enlargement, in LN biopsy, diagnosed AILD, and during treatment expired by sepsis. Since admission, serum total LD activities were increased and serum LD isoenzyme EP showed that LD3-5 fractions was not separated in broad single band. Its pattern was due to LD-immunoglobulin complex, LD-bound immunoglobulin was IgG ,lamda. For the identification of immunoglobulin, we at first did serum protein immunoelectrophoresis. then stained the plate with tetrazolium dye for LD activity.
Biopsy
;
Chills
;
Electrophoresis
;
Fever
;
Humans
;
Immunoblastic Lymphadenopathy*
;
Immunoelectrophoresis
;
Immunoglobulin G
;
Immunoglobulins
;
Lactic Acid*
;
Lymphatic Diseases
;
Sepsis
8.Type III hyperlipoproteinemia associated with generalized tuberoeruptive xanthomas.
Korean Journal of Clinical Pathology 2001;21(4):269-273
A 61-year-old female patient presented with the type III hyperlipoproteinemia (HLP) in association with generalized eruptive and tuberous xanthomas. She had hypercholesterolemia and hypertriglyceridemia, and extensive coronary atherosclerosis. Further studies revealed a positive standing plasma test, abnormal beta-very low density lipoprotein (VLDL) on lipoprotein electrophoresis, markedly elevated very low density lipoprotein-cholesterol (VLDL-C) to plasma triglycerides (TG) ratio (0.86) and homozygosity for apolipoprotein E2. After about one year of therapy with lipid-lowering agents and diet restriction, a significant reduction of serum cholesterol and TG was observed and the yellowish orange discolorations of palmar creases disappeared from her palms.
Apolipoprotein E2
;
Cholesterol
;
Citrus sinensis
;
Coronary Artery Disease
;
Diet
;
Electrophoresis
;
Female
;
Humans
;
Hypercholesterolemia
;
Hyperlipoproteinemia Type III*
;
Hypertriglyceridemia
;
Lipoproteins
;
Middle Aged
;
Plasma
;
Triglycerides
;
Xanthomatosis*
9.Molecular Genetic Analysis of Cis-AB with Cytosine at nucleotide position 467.
Dal Sik KIM ; Hye Soo LEE ; Sam Im CHOI ; Pyoung Han HWANG ; Ho Keun YI
Journal of the Korean Society for Microbiology 1999;34(1):13-20
BACKGROUNDS: The molecular genetic characteristcs of cis-AB blood group have shown that its allele had C, G, C and C at nucleotide positions (nps) 526, 703, 796 and 803, respectively. And all cis-AB analysed and reported molecular genetically in Korea and Japan had T at np 467 (leucine at amino acid position 156). We report a first case of cis-AB with C at np 467 (proline at amino acid position 156). METHODS: Genomic DNA was extracted from peripheral blood of cis-AB patient and amplified by DS1/DS2 and DS3/DS4 allele-specific primers. After PCR, we analysed nps 261, 467, 526, 646, 703, 796, and 803 by restriction digestion, autoradiography and automatic sequencing. RESULTS: PCR-RFLP with DS1/DS2 primers and restriction enzyme KpnI showed that cis-AB had an 0 allele. The results of genomic sequencing, autoradiography and restriction digestion showed that cis-AB allele at nps 467, 526, 646, 703, 796 and 803 had C, C, T, G, C and C, respectively. CONCLUSION: This cis-AB showed characteristic molecular genetic features at nps 526, 703, 796, and 803. And this is a first case of A(Pro) cis-AB with C at np 467. (Korean J Blood Transfusion 10(1): 13-19, 1999)
Alleles
;
Autoradiography
;
Blood Transfusion
;
Cytosine*
;
Digestion
;
DNA
;
Humans
;
Japan
;
Korea
;
Molecular Biology*
;
Polymerase Chain Reaction
10.A speech-phonetic study on the pronunciation of the openbite patients.
Korean Journal of Orthodontics 1991;21(2):287-307
This study aimed at examining speech defects of open bite patients, which were analized in terms of formant frequency for vowels and word pronunciation length for consonants. In addition, the upper and lower lip (perioral m.) activity was tested by the EMG. The tongue force was measured by the strain gauge, and the speech discrimination test was carried out. One experimental group and one control group were used for this study and they were respectively composed of six female openbite patients and six normal-occlusion females. Eight monophthongs, two fricatives and two affricatives were chosen for speech analysis. Speeches of the above-mentioned groups were recorded and then analized by the ILS/PC-I software. Four hundred most frequently used monosyllables were also chosen for discrimination score. Openbite patients showed the following characteristics: 1. Abnormality in case of /a/, /epsilon/, /e/, /i/ F2 and /e/, /a/ F1. 2. Significantly elongated length in their pronunciation of /h/ and /Ch/ and somewhat elongated length also in their pronunciation of /s/ and /c/. 3. Significant upper lip activity according to the EMG test during pronunciation of the bilabial consonants. 4. Relatively weak tongue force according to the strain gauge measurement. 5. According to the speech discrimination test, high rate of misarticulation in case of (a) initial /p/ /s'/ and /ts'/, (b) /a/, /epsilon/, /e/, /je/, /o/, /phi/, /jo/, /u/, /we/, and /i/ (c) final /eta/.
Articulation Disorders
;
Discrimination (Psychology)
;
Female
;
Humans
;
Lip
;
Open Bite*
;
Speech Discrimination Tests
;
Tongue